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Lexicon Pharmaceuticals (LXRX) Stock Price & Analysis
LXRX Stock Chart & Stats
- Day’s Range
- $1.38 - $1.50
- 52-Week Range
- $1.10 - $2.68
- Previous Close
- $1.48
- Volume
- N/A
- Average Volume (3M)
- 2.60M
- Market Cap
- $631.84M
- Enterprise Value
- $919.00M
- Total Cash (Recent Filing)
- $190.61M
- Total Debt (Recent Filing)
- $59.28M
- Price to Earnings (P/E)
- ―
- Beta
- 1.73
- Next Earnings
- Nov 05, 2026 (Est.)
- EPS Estimate
- -0.06
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Deleveraged Balance Sheet
The move to zero debt and higher equity reduces financial risk and gives Lexicon greater flexibility to fund clinical development and commercialization. Although profitability remains unresolved, improved capitalization can support execution and reduce dependence on immediate refinancing while key programs advance.
SONATA-HCM Clinical Progress
Completing and significantly over-enrolling a pivotal Phase III study strengthens the evidence-generation process for Lexicon’s HCM program and may improve statistical power. This creates a defined value inflection and supports the durability of the late-stage pipeline over the next several quarters.
Zynquista Regulatory Advancement
Progress toward satisfying FDA exposure requirements and resubmitting the Zynquista NDA moves the program closer to a potential regulatory decision. That advancement could expand Lexicon’s commercial opportunity and create a clearer path from clinical investment to product revenue.
Bears Say
Persistent Cash Burn
Continued negative operating and free cash flow means Lexicon is not yet funding operations internally and must rely on existing liquidity or external financing. Persistent burn can constrain investment choices and increase dilution or financing pressure if clinical timelines extend or milestones are delayed.
Highly Volatile Revenue Base
The sharp recent revenue contraction highlights how dependent reported results are on irregular commercialization or partner-related receipts rather than a stable recurring base. Such volatility makes forward revenue less predictable and leaves funding capacity sensitive to licensing timing and milestone events.
Persistent Unprofitability And Rising Costs
Lexicon’s strong gross margin does not offset its operating cost base, leaving the company persistently loss-making while investment requirements rise. Sustained R&D and commercial preparation spending may be necessary for pipeline progress, but it also delays breakeven and prolongs reliance on financing.
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Lexicon Pharmaceuticals Stock Smart Score
Company Description
Lexicon Pharmaceuticals
Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to the end-to-end process of identifying, advancing, and bringing to market novel therapeutic compounds. Its development pipeline includes orally administered small molecule drug candidates such as Sotagliflozin, which has successfully concluded Phase III clinical studies for treating both heart failure and type 1 diabetes, and LX9211, currently undergoing Phase II clinical development for neuropathic pain. The firm maintains important strategic collaborations and licensing arrangements with pharmaceutical industry leaders, including Bristol-Myers Squibb Company and Genentech, Inc. Established in 1995, Lexicon Pharmaceuticals, Inc. is based in The Woodlands, Texas.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Michael S. Exton
- Employees
- 81
- Website
- www.lexpharma.com
- Address
- 2445 Technology Forest Boulevard, The Woodlands, TX, 77381, US
Lexicon Pharmaceuticals (LXRX) Earnings & Revenues
LXRX Company Deck
LXRX Earnings Call
Earnings Call SentimentPositive
The call highlighted meaningful clinical and strategic progress — notably the over-enrollment of SONATA-HCM, approaching NDA resubmission for Zynquista supported by favorable STENO1 exposure and DKA data, international regulatory activity, and milestone-driven partnership progress (LX9851) — and the company strengthened liquidity with cash rising to $190.6M and a new Hercules loan facility. Counterbalancing these positives were a steep year-over-year revenue decline (driven by lack of prior-period licensing revenue), a return to a net loss of $31.8M, increased R&D spending, and some timing uncertainty due to reliance on an investigator-led study for NDA formatting and submission. Overall, the call presented strong operational and pipeline momentum alongside expected near-term financial volatility as the company invests in late-stage programs.
View all LXRX earnings summariesLXRX Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 3 | 4 | 15 |
| Technical Analysis | 3 | 4 | 3 |
| Moving Averages | 0 | 0 | 12 |












