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D.Western Therapeutics Institute, Inc. (JP:4576)
:4576
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D.Western Therapeutics Institute (4576) AI Stock Analysis

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JP:4576

D.Western Therapeutics Institute

(4576)

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Neutral 47 (OpenAI - Gpt-5.6Sol)
Rating:47Neutral
Price Target:
¥88.00
▼(-16.19% Downside)
Action:Reiterated
Date:08/07/26
The score is held down primarily by weak financial performance—large ongoing losses and sustained negative free cash flow—despite strong gross margins and some improvement in leverage and cash burn. Technical indicators are mildly supportive in the short term, but the longer-term trend remains pressured. Valuation is not a clear positive because the company is unprofitable and no dividend yield is available.
Positive Factors
Strong Gross Margins
Strong gross margins indicate the underlying products can generate substantial value after direct costs. If sustained, this provides operating leverage and a foundation for improved profitability as development spending and other fixed costs moderate.
Negative Factors
Volatile, Declining Revenue
A small and inconsistent revenue base makes forecasting difficult and limits operating leverage. The 2025 decline indicates that commercial scale and product adoption remain insufficient to absorb the company’s ongoing development and operating cost structure.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong Gross Margins
Strong gross margins indicate the underlying products can generate substantial value after direct costs. If sustained, this provides operating leverage and a foundation for improved profitability as development spending and other fixed costs moderate.
Read all positive factors

D.Western Therapeutics Institute (4576) vs. iShares MSCI Japan ETF (EWJ)

D.Western Therapeutics Institute Business Overview & Revenue Model

Company Description
D. Western Therapeutics Institute, Inc. is a biotechnology enterprise focused on the research, discovery, and innovation of various pharmaceutical drugs. The company's current portfolio includes GLANATEC and GLA-ALPHA, ophthalmic solutions prescri...

D.Western Therapeutics Institute Financial Statement Overview

Summary
Financials are dominated by development-stage risk: revenue is small and volatile, profitability remains deeply negative (net loss exceeding revenue), and cash flow is persistently negative despite improvement in 2025. A key offset is strong gross margin characteristics and a healthier 2025 balance sheet with improved leverage (debt-to-equity ~0.42), but the company is still far from break-even and not self-funding.
Income Statement
32
Negative
Balance Sheet
58
Neutral
Cash Flow
27
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue305.74M387.62M471.58M428.36M448.10M414.42M
Gross Profit251.40M301.24M424.74M391.70M420.53M394.32M
EBITDA-611.48M-572.35M-1.23B-775.59M-390.75M-110.03M
Net Income-651.85M-632.09M-1.29B-812.41M-429.69M-149.00M
Balance Sheet
Total Assets1.97B2.17B1.67B2.37B2.96B2.46B
Cash, Cash Equivalents and Short-Term Investments1.54B1.71B1.13B1.87B2.33B1.93B
Total Debt594.17M605.18M797.98M885.12M967.69M340.00M
Total Liabilities654.26M734.01M935.57M1.09B1.08B427.72M
Stockholders Equity1.31B1.44B733.87M1.28B1.86B2.01B
Cash Flow
Free Cash Flow0.00-496.54M-1.31B-601.76M-364.58M-179.21M
Operating Cash Flow0.00-493.79M-1.30B-586.82M-354.77M-176.31M
Investing Cash Flow0.00-2.45M-10.01M-15.25M-139.89M-111.15M
Financing Cash Flow0.001.08B567.63M134.47M867.30M-104.46M

D.Western Therapeutics Institute Technical Analysis

Technical Analysis Sentiment
Positive
Last Price105.00
Price Trends
50DMA
78.38
Positive
100DMA
81.38
Positive
200DMA
90.77
Negative
Market Momentum
MACD
2.85
Negative
RSI
67.58
Neutral
STOCH
96.30
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4576, the sentiment is Positive. The current price of 105 is above the 20-day moving average (MA) of 81.70, above the 50-day MA of 78.38, and above the 200-day MA of 90.77, indicating a neutral trend. The MACD of 2.85 indicates Negative momentum. The RSI at 67.58 is Neutral, neither overbought nor oversold. The STOCH value of 96.30 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4576.

D.Western Therapeutics Institute Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
¥22.13B-11.716.10%
48
Neutral
¥79.46B-23.80-44.85%31.36%
47
Neutral
¥5.12B-7.39-86.84%-41.25%55.11%
47
Neutral
¥37.40B56.85-47.32%
45
Neutral
¥14.94B-32.46-18.71%-246.54%
42
Neutral
¥9.19B-8.01-56.16%3.12%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4576
D.Western Therapeutics Institute
88.00
-12.00
-12.00%
JP:4592
SanBio Co
998.00
-1,325.00
-57.04%
JP:4593
Healios KK
282.00
-208.00
-42.45%
JP:4599
StemRIM Inc.
351.00
46.00
15.08%
JP:4978
ReproCELL Inc.
149.00
-29.00
-16.29%
JP:7776
CellSeed Inc.
234.00
-207.00
-46.94%

D.Western Therapeutics Institute Corporate Events

D. Western Therapeutics Outlines Q2 FY12/26 Results and Outlook
Aug 13, 2026
D. Western Therapeutics Institute has released briefing materials for its second quarter results for the fiscal year ending December 2026. The documents outline financial performance, progress in business activities, and an updated forecast for th...
D.Western Therapeutics Posts Deeper Losses, Keeps 2026 Outlook Unchanged
Aug 13, 2026
D.Western Therapeutics Institute reported consolidated net sales of ¥33 million for the first half of 2026, an 80.9% year-on-year decline, with an operating loss of ¥312 million and a net loss attributable to owners of the parent of &#16...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 07, 2026