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OncoTherapy Science (4564) AI Stock Analysis

JP:4564

OncoTherapy Science

(TSE/TYO:4564)

Select Model
Rating:42Neutral
Price Target:JPY 16.50â–¼(-8.33% Downside)
Action:reiterated
Date:08/11/26

The low overall score of 42 is heavily influenced by the firm's lack of profitability, severe cash burn, and bearish technical setup. While the exceptional, debt-free balance sheet provides critical operational runway, the negative valuation metrics and downward price trends underscore the high-risk nature of this investment.

Positive Factors
Zero leverageA debt-free balance sheet reduces interest obligations and refinancing exposure, giving the company greater flexibility while it funds oncology research. This capital structure provides a cushion against operating volatility and preserves more strategic options than a heavily leveraged position.
Negative Factors
Persistent cash burnOngoing negative operating and free cash flow means the company is not currently funding its activities through internally generated cash. Continued burn can reduce financial flexibility over the next several quarters and increase the importance of external funding to sustain development.

OncoTherapy Science (4564) vs. iShares MSCI Japan ETF (EWJ)

-30%-20%-10%0%10%20%30%JP:4564-25.00%EWJ+15.87%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
JPY 7.35B
Dividend Yield
―
Average Volume (3M)
183.43M
Price to Earnings (P/E)
-7.6
Beta (1Y)
1.04
Revenue Growth
-8.58%
EPS Growth
19.03%
Country
Japan
Employees
46
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

OncoTherapy Science Business Overview & Revenue Model

Company Description

OncoTherapy Science, Inc. engages in research and development of anti-body drugs; and the genome analysis of cancer, liquid biopsy, and development of new immunotherapy in Japan. Its development pipeline includes OTS167, a small molecular compound th...

How the Company Makes Money

The company’s monetization is generally tied to commercializing oncology drug candidates and related technologies through development and partnering, including potential revenue from licensing/out-licensing, collaborative research arrangements, and m...

OncoTherapy Science Financial Statement Overview

Summary

The company displays the high-risk profile of an early-stage biotech firm, characterized by heavy cash burn and massive operational losses. However, this is partially mitigated by a pristine, debt-free balance sheet that provides essential financial runway.

Income Statement

25Negative

Balance Sheet

82Very Positive

Cash Flow

20Very Negative
Financial statement breakdown
BreakdownTTMMar 2026Mar 2025Mar 2024Mar 2022Mar 2021
Income Statement
Total Revenue749.75M808.53M750.05M610.12M1.13B332.48M
Gross Profit-12.76M13.96M-12.76M-177.72M41.69M19.54M
EBITDA-126.67M-810.38M-14.92M-165.50M-1.10B-1.59B
Net Income-815.05M-910.64M-815.28M-1.29B-1.12B-1.56B
Balance Sheet
Total Assets1.16B2.36B1.16B867.27M1.51B3.37B
Cash, Cash Equivalents and Short-Term Investments833.88M2.09B833.88M527.66M1.12B2.90B
Total Debt51.07M051.07M106.85M00
Total Liabilities426.09M217.37M426.09M513.61M656.27M291.28M
Stockholders Equity729.11M2.14B729.11M353.67M855.17M3.08B
Cash Flow
Free Cash Flow0-984.97M-815.30M-1.23B-800.29M-1.81B
Operating Cash Flow0-922.75M-815.02M-1.23B-794.90M-1.76B
Investing Cash Flow0-63.22M-279.00K-33.35M-20.32M-52.23M
Financing Cash Flow02.24B1.12B671.37M95.95M0

OncoTherapy Science Technical Analysis

Technical Analysis SentimentNegative
Last Price18.00

Price Trends

50DMA20.34Negative
100DMA19.98Negative
200DMA21.04Negative

Market Momentum

MACD-0.87Positive
RSI43.46Neutral
STOCH33.33Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4564, the sentiment is Negative. The current price of 18.00 is below the 20-day moving average (MA) of 18.60, below the 50-day MA of 20.34, and below the 200-day MA of 21.04, indicating a bearish trend. The MACD of -0.87 indicates Positive momentum. The RSI at 43.46 is Neutral, neither overbought nor oversold. The STOCH value of 33.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4564.

OncoTherapy Science Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

JP:4564 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
JP:4565JP:456561NeutralJPY 133.37B-16.67-8.51%―23.72%12.48%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
JP:4588JP:458850NeutralJPY 223.32B-137.55――1662.38%42.86%
JP:4579JP:457943NeutralJPY 16.61B71.28――20.64%―
JP:4564JP:456442NeutralJPY 7.35B-7.63-42.79%―-8.58%19.03%
JP:4571JP:457142NeutralJPY 7.18B-5.87-33.61%―74.24%-7.78%
JP:4587JP:458742NeutralJPY 145.02B-39.74-7.17%―0.62%27.66%

* Healthcare Sector Average

Performance Comparison

0%200%400%600%800%JP:4564JP:4587JP:4565JP:4571JP:4579JP:4588Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
JP:4564 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
JP:4564OncoTherapy Science, Inc.18.00-6.00-25.00%
JP:4587Peptidream 1117.00-414.00-27.04%
JP:4565Sosei Group Corporation1440.00544.0060.71%
JP:4571NanoCarrier Co., Ltd.79.00-81.00-50.63%
JP:4579RaQualia Pharma Inc.638.00110.0020.83%
JP:4588Oncolys BioPharma, Inc.7560.006795.00888.24%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Aug 11, 2026