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OncoTherapy Science (4564) AI Stock Analysis

2 Followers
JP:4564

OncoTherapy Science

(TSE/TYO:4564)

Select Model
Rating:41Neutral
Price Target:JPY 16.00â–²(0.00% Upside)
Action:reiterated
Date:11/12/26

The overall score is very low, driven primarily by weak technical momentum and a lack of profitability. The stock is in a clear downtrend with all technical indicators pointing to continued weakness. The company's negative earnings and cash flow present significant fundamental risks. The primary mitigating factor is a pristine, debt-free balance sheet, which provides a financial cushion but is not enough to offset the near-term operational and market headwinds.

Positive Factors
Debt-Free Balance SheetZero debt and a 0.0 debt-to-equity ratio reduce fixed financial obligations, while the material increase in equity in 2026 provides a larger capital cushion. This improves resilience and preserves flexibility as the company funds oncology development.
Negative Factors
Declining and Volatile RevenueVolatile and declining revenue makes the commercial base less predictable and weakens operating leverage. Without sustained top-line expansion, the company has less ability to absorb research costs, convert gross-margin gains into earnings, or reduce dependence on capital sources.

OncoTherapy Science (4564) vs. iShares MSCI Japan ETF (EWJ)

-30%-20%-10%0%10%20%30%40%50%JP:4564-27.27%EWJ+16.06%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
JPY 6.53B
Dividend Yield
―
Average Volume (3M)
188.56M
Price to Earnings (P/E)
-7.0
Beta (1Y)
1.04
Revenue Growth
-25.56%
EPS Growth
17.01%
Country
Japan
Employees
46
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

OncoTherapy Science Business Overview & Revenue Model

Company Description

OncoTherapy Science, Inc. engages in research and development of anti-body drugs; and the genome analysis of cancer, liquid biopsy, and development of new immunotherapy in Japan. Its development pipeline includes OTS167, a small molecular compound th...

OncoTherapy Science Financial Statement Overview

Summary

Financial performance is mixed. The balance sheet is a major strength with no debt and a 91% equity-to-assets ratio, providing a solid runway. However, the income statement and cash flow are weak, marked by declining revenue, persistent net losses, and significant negative free cash flow, which are typical but high-risk for a clinical-stage biotech.

Income Statement

22Negative

Balance Sheet

85Very Positive

Cash Flow

25Negative
Financial statement breakdown
BreakdownTTMMar 2026Mar 2025Mar 2024Mar 2022Mar 2021
Income Statement
Total Revenue749.75M808.53M750.05M610.12M1.13B332.48M
Gross Profit-12.76M13.96M-12.76M-177.72M41.69M19.54M
EBITDA-126.67M-810.38M-14.92M-165.50M-1.10B-1.59B
Net Income-815.05M-910.64M-815.28M-1.29B-1.12B-1.56B
Balance Sheet
Total Assets1.16B2.36B1.16B867.27M1.51B3.37B
Cash, Cash Equivalents and Short-Term Investments833.88M2.09B833.88M527.66M1.12B2.90B
Total Debt51.07M051.07M106.85M00
Total Liabilities426.09M217.37M426.09M513.61M656.27M291.28M
Stockholders Equity729.11M2.14B729.11M353.67M855.17M3.08B
Cash Flow
Free Cash Flow0-984.97M-815.30M-1.23B-800.29M-1.81B
Operating Cash Flow0-922.75M-815.02M-1.23B-794.90M-1.76B
Investing Cash Flow0-63.22M-279.00K-33.35M-20.32M-52.23M
Financing Cash Flow02.24B1.12B671.37M95.95M0

OncoTherapy Science Technical Analysis

Technical Analysis SentimentNegative
Last Price16.00

Price Trends

50DMA19.54Negative
100DMA19.75Negative
200DMA20.77Negative

Market Momentum

MACD-0.82Negative
RSI35.75Neutral
STOCH33.33Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4564, the sentiment is Negative. The current price of 16.00 is below the 20-day moving average (MA) of 17.25, below the 50-day MA of 19.54, and below the 200-day MA of 20.77, indicating a bearish trend. The MACD of -0.82 indicates Negative momentum. The RSI at 35.75 is Neutral, neither overbought nor oversold. The STOCH value of 33.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4564.

OncoTherapy Science Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

JP:4564 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
JP:4565JP:456566NeutralJPY 167.91B-30.31-8.51%―23.72%12.48%
JP:4588JP:458855NeutralJPY 248.42B-152.49――1748.97%35.11%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
JP:4587JP:458748NeutralJPY 138.26B-47.42-5.85%―14.25%50.07%
JP:4579JP:457943NeutralJPY 16.82B72.18――31.84%―
JP:4571JP:457141NeutralJPY 6.10B-4.98-33.61%―48.92%-46.91%
JP:4564JP:456441NeutralJPY 6.53B-6.96-42.81%―-25.56%17.01%

* Healthcare Sector Average

Performance Comparison

0%200%400%600%JP:4564JP:4587JP:4565JP:4571JP:4579JP:4588Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
JP:4564 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
JP:4564OncoTherapy Science, Inc.16.00-7.00-30.43%
JP:4587Peptidream 1065.00-518.50-32.74%
JP:4565Sosei Group Corporation1813.00954.00111.06%
JP:4571NanoCarrier Co., Ltd.67.00-83.00-55.33%
JP:4579RaQualia Pharma Inc.646.00105.0019.41%
JP:4588Oncolys BioPharma, Inc.8410.007342.00687.45%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Nov 11, 2026