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AnGes (4563) AI Stock Analysis

1 Followers
JP:4563

AnGes

(TSE/TYO:4563)

Select Model
Rating:39Underperform
Price Target:JPY 24.50â–¼(-5.77% Downside)
Action:reiterated
Date:09/12/26

The low overall score is primarily driven by massive cash burn, severe unprofitability, and a rapidly deteriorating equity base that threatens the company's long-term solvency. Technical indicators display a steep downtrend with strong bearish momentum, while negative valuation metrics further underscore the extreme risk associated with this development-stage biotechnology stock.

Positive Factors
Revenue GrowthAccelerating revenue indicates that AnGes is progressing beyond an early development-only profile and generating greater commercial or collaboration activity. If this trajectory continues, increasing scale could support broader pipeline investment and gradually improve operating leverage over the next several quarters.
Negative Factors
Persistent UnprofitabilityPersistent operating and net losses show that AnGes has not yet established durable earnings power, despite stronger revenue growth. Continued losses can constrain internal investment capacity and make future performance dependent on successful product development, commercialization, or additional financing.

AnGes (4563) vs. iShares MSCI Japan ETF (EWJ)

-80%-60%-40%-20%0%20%40%JP:4563-65.33%EWJ+10.53%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
JPY 143.66M
Dividend Yield
―
Average Volume (3M)
1.77M
Price to Earnings (P/E)
-2.7
Beta (1Y)
0.60
Revenue Growth
35.28%
EPS Growth
90.12%
Country
Japan
Employees
56
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

AnGes Business Overview & Revenue Model

Company Description

AnGes, Inc., a biopharmaceutical firm headquartered in Ibaraki, Japan, and established in 1999, focuses on pioneering the research and development of gene-based medical solutions. Its primary therapeutic asset is Hepatocyte Growth Factor (HGF) Plasmi...

How the Company Makes Money

AnGes primarily makes money by monetizing its biotechnology pipeline and approved products through a combination of product-related revenue and collaboration-based income. Revenue can include (1) sales of any commercialized products the company has o...

AnGes Financial Statement Overview

Summary

The company exhibits a high-risk financial profile with severe unprofitability and a massive free cash flow deficit of 5.76 billion. Despite 23% top-line revenue growth and low debt, a drastically depleted equity base (plummeting from 26 billion to 3 billion) raises immediate solvency and dilution concerns.

Income Statement

18Very Negative

Balance Sheet

25Negative

Cash Flow

12Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue961.90M874.12M643.00M152.99M67.06M64.15M
Gross Profit398.00M320.38M247.00M19.45M-26.83M7.43M
EBITDA-5.51B-5.09B-5.74B-8.86B-13.41B-13.21B
Net Income-3.87B-5.12B-28.13B-7.44B-14.71B-13.68B
Balance Sheet
Total Assets3.66B5.41B4.67B28.89B38.82B45.46B
Cash, Cash Equivalents and Short-Term Investments296.72M1.88B1.71B4.16B11.04B17.90B
Total Debt723.78M54.37M272.45M362.68M1.16B0
Total Liabilities3.45B2.33B2.51B2.79B8.40B6.82B
Stockholders Equity205.68M3.08B2.16B26.10B30.43B38.63B
Cash Flow
Free Cash Flow-1.38B-5.76B-6.69B-8.84B-11.23B-11.46B
Operating Cash Flow-1.38B-5.75B-6.61B-8.74B-11.21B-11.38B
Investing Cash Flow-80.00K18.48M-130.80M-356.65M-97.14M-154.87M
Financing Cash Flow567.54M5.90B4.20B2.04B3.57B17.38B

AnGes Technical Analysis

Technical Analysis SentimentNegative
Last Price26.00

Price Trends

50DMA34.84Negative
100DMA41.24Negative
200DMA48.78Negative

Market Momentum

MACD-2.46Positive
RSI22.27Positive
STOCH11.11Positive

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4563, the sentiment is Negative. The current price of 26.00 is below the 20-day moving average (MA) of 30.60, below the 50-day MA of 34.84, and below the 200-day MA of 48.78, indicating a bearish trend. The MACD of -2.46 indicates Positive momentum. The RSI at 22.27 is Positive, neither overbought nor oversold. The STOCH value of 11.11 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4563.

AnGes Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

JP:4563 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
JP:4565JP:456567NeutralJPY 146.80B-28.89-8.51%―23.72%12.48%
JP:4588JP:458854NeutralJPY 233.66B-144.29――1662.38%42.86%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
JP:4593JP:459348NeutralJPY 35.38B50.40――-47.32%―
JP:7774JP:777442NeutralJPY 24.16B-56.73――17.05%10.47%
JP:4563JP:456339UnderperformJPY 11.13B-2.73-163.39%―35.28%90.12%

* Healthcare Sector Average

Performance Comparison

0%200%400%600%800%JP:4563JP:4565JP:4588JP:4593JP:7774Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
JP:4563 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
JP:4563AnGes 26.00-53.00-67.09%
JP:4565Sosei Group Corporation1729.00948.00121.38%
JP:4588Oncolys BioPharma, Inc.7550.006699.00787.19%
JP:4593Healios KK245.00-222.00-47.54%
JP:7774Japan Tissue Engineering Co., Ltd.601.00138.0029.81%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Sep 12, 2026