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International Stem Cell Corp (ISCO)
:ISCO
US Market

International Stem Cell (ISCO) AI Stock Analysis

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International Stem Cell

(OTC:ISCO)

45Neutral
International Stem Cell's stock is rated low due to significant financial challenges, including negative profitability and high leverage. While there is some positive momentum in technical analysis, the valuation remains unattractive due to the lack of profitability. Improvements in financial stability and strategic changes are necessary to enhance the overall stock rating.

International Stem Cell (ISCO) vs. S&P 500 (SPY)

International Stem Cell Business Overview & Revenue Model

Company DescriptionInternational Stem Cell Corporation, a clinical stage biotechnology company, focuses on the development of therapeutic and biomedical products in North America, Asia, Europe, and internationally. The company's products are based on human parthenogenetic stem cells, a proprietary type of pluripotent stem cell. It develops various cell types, including neural stem cells for the treatment of Parkinson's disease and other central nervous system disorders; and develops, manufactures, and markets anti-aging skincare and human cell culture products. The company's human cell culture products include human skin cells and reagents for the study of skin disease, toxicology, or wound healing; human cells from the heart and blood vessels, and reagents to study cardiovascular disease and cancer; human bronchial and tracheal cell lines for the study of toxicity, cystic fibrosis, asthma, and pathogenesis; and human mammary epithelial cell lines for the study of breast cancer, three dimensional culture, and carcinogen screening. Its human cell culture products also comprise adult stem cells and reagents for regenerative medicine; human prostate cells and specialized medium to study prostate disease; human renal and bladder cells and media to study renal and bladder diseases; human corneal cells and media for the study of corneal disease; human female reproductive system cells for the study of cellular physiology; human skeletal muscle cells for the study of biology, diabetes, insulin receptor studies, muscle metabolism, muscle tissue repair, and myotube development; and other cell culture reagents and supplements for the growth, staining, and freezing of human cells. The company sells skincare products through a website and professional channels; and human cell culture products through its sales force, OEM partners, and brand distributors. International Stem Cell Corporation was founded in 2001 and is headquartered in San Diego, California.
How the Company Makes MoneyISCO generates revenue through multiple streams, primarily from the sale of biomedical products, licensing agreements, and partnerships. The company develops and sells specialized cell culture media and reagents used in stem cell research and therapy development. Additionally, ISCO has a skincare product line under the brand 'Lifeline Skin Care,' which leverages its stem cell technology. Revenue is also derived from strategic partnerships and collaborations with other biotech firms and research institutions, which may include joint development agreements, licensing its proprietary technologies, and receiving milestone and royalty payments.

International Stem Cell Financial Statement Overview

Summary
International Stem Cell faces significant financial challenges, with consistent losses and high leverage. Revenue growth is a positive aspect, but profitability and cash flow issues persist. Financial restructuring or strategic changes may be needed to improve stability and reduce debt reliance.
Income Statement
45
Neutral
The company has shown moderate revenue growth, with a 16.6% increase from 2023 to 2024. However, consistent negative net income and EBIT margins indicate ongoing operational challenges. Gross profit margin is healthy at 58.6% for 2024, but the net profit margin remains negative at -2.3%, showing profitability issues.
Balance Sheet
30
Negative
The balance sheet is weak due to high leverage, with a debt-to-equity ratio of 1.20 for 2024. Although stockholders' equity turned positive, it remains low. The equity ratio is concerning at 7.2%, indicating significant reliance on debt. Improving equity levels could enhance financial stability.
Cash Flow
40
Negative
Free cash flow turned negative in 2024, dropping significantly from the previous year. The operating cash flow to net income ratio is positive, but the overall cash flow position is weak, with a free cash flow to net income ratio of 0.73. Persistent cash flow challenges pose liquidity risks.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
9.09M7.79M8.18M7.18M7.13M
Gross Profit
5.32M4.61M4.91M4.24M4.35M
EBIT
-68.00K-663.00K-196.00K-1.92M-2.82M
EBITDA
142.00K202.00K22.00K-220.00K-2.36M
Net Income Common Stockholders
-209.00K-131.00K-466.00K-1.04M-2.84M
Balance SheetCash, Cash Equivalents and Short-Term Investments
1.23M1.59M742.00K171.00K689.00K
Total Assets
5.17M5.39M5.13M4.95M5.29M
Total Debt
3.84M4.18M4.28M4.07M4.32M
Net Debt
2.61M2.59M3.53M3.90M3.63M
Total Liabilities
9.10M5.28M9.65M9.53M9.62M
Stockholders Equity
-3.93M113.00K-4.52M-4.59M-4.33M
Cash FlowFree Cash Flow
-153.00K846.00K321.00K-1.34M-449.00K
Operating Cash Flow
13.00K929.00K332.00K-1.30M-341.00K
Investing Cash Flow
-171.00K-83.00K-11.00K-45.00K-108.00K
Financing Cash Flow
-200.00K0.00250.00K824.00K654.00K

International Stem Cell Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.12
Price Trends
50DMA
0.11
Positive
100DMA
0.11
Positive
200DMA
0.09
Positive
Market Momentum
MACD
<0.01
Positive
RSI
54.72
Neutral
STOCH
33.33
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ISCO, the sentiment is Positive. The current price of 0.12 is above the 20-day moving average (MA) of 0.12, above the 50-day MA of 0.11, and above the 200-day MA of 0.09, indicating a bullish trend. The MACD of <0.01 indicates Positive momentum. The RSI at 54.72 is Neutral, neither overbought nor oversold. The STOCH value of 33.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ISCO.

International Stem Cell Risk Analysis

International Stem Cell disclosed 47 risk factors in its most recent earnings report. International Stem Cell reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

International Stem Cell Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$5.04B3.15-44.58%2.85%16.08%-0.27%
UPUPC
51
Neutral
$1.06M
45
Neutral
$1.00M-246.40%16.64%27.03%
40
Underperform
$8.27M234.90%62.35%
28
Underperform
$3.18M-120.01%97.84%
23
Underperform
$550.01K-174.06%-10.75%82.25%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ISCO
International Stem Cell
0.12
0.02
20.00%
SCPX
Scorpius Holdings
0.04
-20.66
-99.81%
BCLI
Brainstorm Cell Therapeutics
1.32
-6.48
-83.08%
WINT
Windtree Therapeutics
0.83
-223.67
-99.63%
UPC
Universe Pharmaceuticals
4.91
-1,549.09
-99.68%
Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.