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Innate Pharma (IPHA) AI Stock Analysis
Innate Pharma
(NASDAQ:IPHA)
The score is held back primarily by weak financial performance—sharp revenue contraction, ongoing heavy losses and cash burn, and negative shareholders’ equity. The latest earnings call meaningfully offsets this with positive guidance, multiple upcoming clinical catalysts, and an extended cash runway into Q1 2028. Technical signals remain soft (negative MACD and below key moving averages), while valuation is difficult to assess with a negative P/E and no dividend support.
Innate Pharma (IPHA) vs. SPDR S&P 500 ETF (SPY)
- Market Cap
- $150.35M
- Dividend Yield
- ―
- Average Volume (3M)
- 159.15K
- Price to Earnings (P/E)
- -2.4
- Beta (1Y)
- 0.69
- Revenue Growth
- -24.21%
- EPS Growth
- 1.17%
- Country
- US
- Employees
- 163
- Sector
- Healthcare
- Sector Strength
- 51
- Industry
- Biotechnology
Innate Pharma Business Overview & Revenue Model
Company Description
Innate Pharma S.A. is a biotechnology firm, founded in 1999 and headquartered in Marseille, France, that specializes in the discovery, development, and market introduction of therapeutic antibodies. The company primarily targets oncology indications...
Innate Pharma Earnings Call Summary
The call conveyed a strongly positive outlook, with the lacutamab partnership closing, Phase 3 initiation, preliminary IPH4.5 thousand objective responses and favorable safety observations, completed monalizumab enrollment, multiple upcoming catalysts, and a cash runway expected through the end of the first quarter of 2028. The main qualifications were that IPH4.5 thousand data remain early, the post-enfortumab vedotin urothelial cancer setting lacks an established second-line standard, and broader development could require additional funding.
Q2-2026 Updates
Positive Updates
Negative Updates
Company Guidance
Innate is targeting the first patient in TELLOMAK-3 in Q1 2027, with the first patient expected in the first quarter of 2027 and a filing for accelerated approval in Sezary Syndrome currently planned for the second half of 2027; initial Phase 1 dose escalation data for IPH4.5 thousand are expected on November 18, 2026, with approximately 15 patients enrolled in both post TB urothelial cancer, head and neck cancer, and somewhat lower enrollment in the non-small cell lung cancer cohort; the PACIFIC-9 Phase 3 readout remains expected in the second half of 2026, with a press release from AstraZeneca and Innate also looking to press release that as well and potentially do some calls; the $75 million Sobi upfront payment and €30 million equity offering, representing €28 million in expected net proceeds, are expected to extend cash runway through the end of the first quarter of 2028; lacutamab pricing research established a range of $500 thousand to $650 thousand per patient per annum; and the €30 million raise funds the initial steps into dose optimization, while broadening the program across additional tumor types would require additional funding.
Innate Pharma Financial Statement Overview
Summary
Weak fundamentals driven by sharply lower 2025 revenue (~48% YoY), sustained large operating losses and deeply negative margins, and persistent negative operating/free cash flow (notably ~-$50.7M operating cash flow in 2025). A major risk is shareholders’ equity turning negative in 2025, signaling elevated solvency/dilution pressure despite some debt reduction and modest year-over-year improvement in free cash flow.
Income Statement
18Very NegativeBalance Sheet
22NegativeCash Flow
17Very Negative| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 1.08M | 2.79M | 12.62M | 51.90M | 57.67M | 12.11M |
| Gross Profit | 18.45M | 2.79M | 12.62M | 5.62M | 6.01M | -22.30M |
| EBITDA | -51.94M | -43.65M | -46.91M | -1.84M | -12.28M | -43.23M |
| Net Income | -47.51M | -49.18M | -49.47M | -7.57M | -58.10M | -52.81M |
Balance Sheet | ||||||
| Total Assets | 34.71M | 62.69M | 111.06M | 175.19M | 207.86M | 267.50M |
| Cash, Cash Equivalents and Short-Term Investments | 10.89M | 34.30M | 80.77M | 92.46M | 101.48M | 119.84M |
| Total Debt | 20.20M | 22.56M | 31.00M | 39.89M | 42.25M | 44.25M |
| Total Liabilities | 75.20M | 84.39M | 102.22M | 132.29M | 153.71M | 160.06M |
| Stockholders Equity | -40.49M | -21.69M | 8.83M | 51.90M | 54.15M | 107.44M |
Cash Flow | ||||||
| Free Cash Flow | -44.90M | -34.91M | -7.29M | -34.91M | -20.28M | -59.79M |
| Operating Cash Flow | -44.72M | -32.56M | -6.90M | -32.56M | -19.15M | -58.46M |
| Investing Cash Flow | 2.81M | 20.63M | 9.20M | 20.63M | 1.88M | -917.00K |
| Financing Cash Flow | -6.11M | -1.97M | -6.01M | -1.97M | -1.83M | 26.82M |
Innate Pharma Technical Analysis
Price Trends
Market Momentum
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IPHA, the sentiment is Negative. The current price of 1.41 is below the 20-day moving average (MA) of 1.50, below the 50-day MA of 1.75, and below the 200-day MA of 1.71, indicating a bearish trend. The MACD of -0.07 indicates Negative momentum. The RSI at 36.70 is Neutral, neither overbought nor oversold. The STOCH value of 27.59 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for IPHA.
Innate Pharma Risk Analysis
Innate Pharma disclosed 89 risk factors in its most recent earnings report. Innate Pharma reported the most risks in the "Tech & Innovation" category.
Latest Risks Added
1 New RiskInnate Pharma Peers Comparison
Overall Rating
IPHA51Neutral
VOR50Neutral
SLS45Neutral
ELTX42Neutral
Financial Indicators
| Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
| Sector * | 51Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% |
| 51Neutral | $156.91M | -2.39 | 152.56% | ― | -24.21% | 1.17% | |
| 50Neutral | $1.16B | 0.06 | -830.38% | ― | ― | ― | |
| 45Neutral | $1.95B | -40.46 | -35.91% | ― | ― | 35.38% | |
| 42Neutral | $45.51M | -0.75 | -1266.43% | ― | ― | 49.43% |
* Healthcare Sector Average
Performance Comparison
| Show on chart | Ticker | Company Name | Price | Change | % Change |
|---|---|---|---|---|---|
| IPHA | Innate Pharma SA Sponsored ADR | 1.40 | -0.42 | -23.08% | |
| SLS | Sellas Life Sciences Group | 8.55 | 6.87 | 408.93% | |
| ELTX | Elicio Therapeutics, Inc | 1.59 | -7.54 | -82.58% | |
| VOR | Vor Biopharma, Inc. | 19.25 | -1.66 | -7.94% |
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.
Date of analysis: Sep 22, 2026