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Ionis Pharmaceuticals (IONS) Stock Statistics & Valuation Metrics

Total Valuation

Ionis Pharmaceuticals has a market cap or net worth of $7.23B. The enterprise value is $13.25B.

Market Cap
$7.23B
Enterprise Value
$13.25B

Share Statistics

Ionis Pharmaceuticals has 166,184,330 shares outstanding. The number of shares has decreased by -2.65% in one year.

Shares Outstanding
166,184,330
Owned by Insiders
0.78%
Owned by Institutions
63.97%

Financial Efficiency

Ionis Pharmaceuticals’s return on equity (ROE) is -0.78 and return on invested capital (ROIC) is -11.96%.

Return on Equity (ROE)
-0.78
Return on Assets (ROA)
-0.11
Return on Invested Capital (ROIC)
-11.96%
Return on Capital Employed (ROCE)
-0.14
Revenue Per Employee
637.84K
Profits Per Employee
-257.43K
Employee Count
1,480
Asset Turnover
0.27
Inventory Turnover
1.59

Valuation Ratios

The current PE Ratio of Ionis Pharmaceuticals is -12.58. Ionis Pharmaceuticals’s PEG ratio is 0.15.

PE Ratio
-12.58
PS Ratio
8.28
PB Ratio
16.37
Price to FCF
-12.94
Price to Operating Cash Flow
-14.50
PEG Ratio
0.15

Income Statement

In the last 12 months, Ionis Pharmaceuticals had revenue of 944.00M and earned -381.00M in profits. Earnings per share was -2.38.

Revenue
944.00M
Gross Profit
928.00M
Operating Income
-382.00M
Pretax Income
-380.00M
Net Income
-381.00M
EBITDA
-284.31M
Earnings Per Share (EPS)
-2.38

Cash Flow

In the last 12 months, operating cash flow was -496.43M and capital expenditures -62.44M, giving a free cash flow of -558.88M billion.

Operating Cash Flow
-496.43M
Free Cash Flow
-558.88M
Free Cash Flow per Share
-3.38

Dividends & Yields

Ionis Pharmaceuticals pays an annual dividend of ―, resulting in a dividend yield of ―

Dividend Per Share
―
Dividend Yield
―
Payout Ratio
N/A
Free Cash Flow Yield
-7.73%
Earnings Yield
-7.85%

Stock Price Statistics

Beta
0.93
52-Week Price Change
-41.32%
50-Day Moving Average
48.99
200-Day Moving Average
66.71
Relative Strength Index (RSI)
43.14
Average Volume (3m)
3.14M

Important Dates

Ionis Pharmaceuticals upcoming earnings date is Nov 04, 2026, TBA (Not Confirmed).

Last Earnings Date
Jul 29, 2026
Next Earnings Date
Nov 04, 2026
Ex-Dividend Date
―

Financial Position

Ionis Pharmaceuticals as a current ratio of 3.83, with Debt / Equity ratio of 534.53%

Current Ratio
3.83
Quick Ratio
3.81
Debt to Market Cap
0.19
Net Debt to EBITDA
-7.89
Interest Coverage Ratio
-4.22

Taxes

In the past 12 months, Ionis Pharmaceuticals has paid 1.00M in taxes.

Income Tax
1.00M
Effective Tax Rate
-0.00

Enterprise Valuation

Ionis Pharmaceuticals EV to EBITDA ratio is -19.38, with an EV/FCF ratio of -16.64.

EV to Sales
10.64
EV to EBITDA
-19.38
EV to Free Cash Flow
-16.64
EV to Operating Cash Flow
-18.74

Balance Sheet

Ionis Pharmaceuticals has $2.05B in cash and marketable securities with $2.42B in debt, giving a net cash position of -$363.89M billion.

Cash & Marketable Securities
$2.05B
Total Debt
$2.42B
Net Cash
-$363.89M
Net Cash Per Share
-$2.19
Tangible Book Value Per Share
$2.65

Margins

Gross margin is 98.16%, with operating margin of -68.09%, and net profit margin of -64.64%.

Gross Margin
98.16%
Operating Margin
-68.09%
Pretax Margin
-64.33%
Net Profit Margin
-64.64%
EBITDA Margin
-54.92%
EBIT Margin
-57.44%

Analyst Forecast

The average price target for Ionis Pharmaceuticals is $84.78, which is 11.43% higher than the current price. The consensus rating is Strong Buy

Price Target
$84.78
Price Target Upside
94.80% Upside
Analyst Consensus
Strong Buy
Analyst Count
19
Revenue Growth Forecast
-7.49%
EPS Growth Forecast
-98.12%

Scores

Smart Score
8
AI Score
48