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BeOne Medicines Ltd (6160) AI Stock Analysis

HK:6160

BeOne Medicines Ltd

(HKEX:6160)

Select Model
Rating:66Neutral
Price Target:HKD 227.00â–²(2.53% Upside)
Action:reiterated
Date:08/09/26

The score is driven primarily by improving financial performance (return to profitability, very strong gross margins, and solid free-cash-flow generation) and supportive technical momentum (price above key moving averages with positive MACD). These positives are meaningfully offset by stretched valuation (high P/E) and the need to prove durability of the turnaround given slower recent revenue growth and prior years of weak cash-flow consistency.

Positive Factors
Profitability and marginsThe return to profitability, combined with consistently very high gross margins, indicates stronger earnings economics and meaningful product value. If maintained, this margin structure can support reinvestment in oncology research, commercialization, and expansion while improving resilience over the next several quarters.
Negative Factors
Slowing revenue growthRevenue growth has decelerated despite the return to profitability, making future earnings expansion more dependent on execution, new indications, and sustained product uptake. Slower top-line growth can limit operating leverage and makes it harder for the company to compound results at its historical pace.

BeOne Medicines Ltd (6160) vs. iShares MSCI Hong Kong ETF (EWH)

-20%-10%0%10%20%30%HK:6160+20.46%EWH+7.37%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
HKD 300.11B
Dividend Yield
―
Average Volume (3M)
3.62M
Price to Earnings (P/E)
62.0
Beta (1Y)
0.87
Revenue Growth
34.73%
EPS Growth
―
Country
Hong Kong
Employees
12,000
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

BeOne Medicines Ltd Business Overview & Revenue Model

Company Description

BeOne Medicines Ltd. is a global oncology company domiciled in Switzerland that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. The firm portfolio spanning hematology and solid...

How the Company Makes Money

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BeOne Medicines Ltd Earnings Call Summary

Earnings Call Date:Aug 27, 2025(Q2-2025)|% Change Since:23.89%|Next Earnings Date:Nov 05, 2026
Earnings Call SentimentPositive

The earnings call reflects a strong performance by BeOne, with significant revenue growth driven by BRUKINSA's market leadership and robust R&D advancements. However, challenges remain due to aggressive competition and potential regulatory impacts. Overall, the positive aspects significantly outweigh the challenges.

Positive Updates

Significant Revenue Growth
BeOne's revenue reached $1.3 billion, representing a 42% year-on-year growth.

Negative Updates

Competition and Pricing Challenges
Despite strong market position, competition aggressively discounting in the BTK market.

Company Guidance

During the Q2 2025 earnings call for BeOne Medicines, the company provided strong financial guidance and updates on their strategic priorities. The company reported a revenue of $1.3 billion for the second quarter, marking a 42% year-over-year increase. BRUKINSA, the leading BTK inhibitor in the U.S. market, contributed $950 million to the global revenue, showcasing a 49% year-over-year growth. The company's gross margin improved to approximately 87%, attributed to favorable product mix and production cost efficiencies. The financial guidance for the full fiscal year 2025 was updated, with total revenue expectations ranging between $5 billion and $5.3 billion. The operating expenses are projected to remain between $4.1 billion and $4.4 billion, with a commitment to achieving positive GAAP operating income and generating positive free cash flow. The company also highlighted several upcoming R&D milestones, including global filings and pivotal data readouts for their key pipeline assets. Overall, BeOne Medicines emphasized their robust execution, strong market positioning, and continued focus on innovation and growth across their oncology portfolio.

BeOne Medicines Ltd Financial Statement Overview

Summary

Overall fundamentals show a credible inflection: profitability has returned (net margin ~8.9%, EBIT margin ~11.9%) with very strong gross margins (~87%) and solid free-cash-flow generation (~1.31B, ~19.6% growth). Key risks are slowing revenue growth (~6.8%) and the need to prove consistency after materially negative cash flows in 2022–2024; leverage is manageable (debt-to-equity ~0.43) but trending up versus 2025.

Income Statement

72Positive

Balance Sheet

66Positive

Cash Flow

74Positive
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue6.12B5.35B3.81B2.46B1.42B1.18B
Gross Profit5.38B4.56B3.22B2.08B-511.06M-447.86M
EBITDA1.10B589.69M-396.44M-1.12B-1.72B-1.39B
Net Income654.97M287.36M-644.79M-881.71M-2.00B-1.46B
Balance Sheet
Total Assets9.18B8.23B5.92B5.81B6.38B8.65B
Cash, Cash Equivalents and Short-Term Investments5.10B4.59B2.63B3.17B4.53B6.62B
Total Debt1.14B1.09B1.08B930.18M596.67M694.64M
Total Liabilities4.00B3.84B2.59B2.27B2.00B2.40B
Stockholders Equity5.17B4.36B3.33B3.54B4.38B6.24B
Cash Flow
Free Cash Flow1.31B943.13M-669.77M-1.75B-1.97B-1.61B
Operating Cash Flow1.49B1.13B-140.63M-1.16B-1.50B-1.30B
Investing Cash Flow-182.66M-276.56M-548.35M60.00M1.08B640.66M
Financing Cash Flow1.12B1.06B193.45M416.48M-18.97M3.64B

BeOne Medicines Ltd Technical Analysis

Technical Analysis SentimentPositive
Last Price221.40

Price Trends

50DMA217.99Positive
100DMA202.48Positive
200DMA195.31Positive

Market Momentum

MACD1.98Positive
RSI52.17Neutral
STOCH28.66Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:6160, the sentiment is Positive. The current price of 221.40 is above the 20-day moving average (MA) of 219.15, above the 50-day MA of 217.99, and above the 200-day MA of 195.31, indicating a bullish trend. The MACD of 1.98 indicates Positive momentum. The RSI at 52.17 is Neutral, neither overbought nor oversold. The STOCH value of 28.66 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HK:6160.

BeOne Medicines Ltd Risk Analysis

BeOne Medicines Ltd disclosed 93 risk factors in its most recent earnings report. BeOne Medicines Ltd reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

2 New Risks
1.Below is a summary of the material factors that make an investment in our ADSs listed on Nasdaq, our ordinary shares listed on the Stock Exchange of Hong Kong Limited, and our ordinary shares issued to permitted investors in China and listed and traded on the Science and Technology Innovation Board of the Shanghai Stock Exchange in Renminbi ("RMB Shares") speculative or risky. This summary does not address all of the risks that we face. Additional discussion of the risks summarized in this risk factor summary, and other risks that we face, are set forth herein and should be carefully considered, together with other information in this Quarterly Report and our other filings with the U.S. Securities and Exchange Commission ("SEC"), before making an investment decision regarding our ADSs, ordinary shares or RMB Shares.Q1, 2026
2.The risk factors denoted with a "*", if any, are newly added or have been materially updated from our Annual Report on Form 10-K for the year ended December 31, 2025 (the "Annual Report").Q1, 2026

BeOne Medicines Ltd Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

HK:6160 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
HK:9995HK:999566NeutralHKD 51.82B7.89105.60%―292.84%―
HK:6160HK:616066NeutralHKD 324.82B62.0414.22%―34.73%―
HK:2696HK:269665NeutralHKD 26.75B26.1820.41%―32.63%8.74%
HK:1801HK:180163NeutralHKD 139.32B95.596.06%―42.64%9.67%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
HK:9926HK:992642NeutralHKD 76.70B-66.50-10.86%―42.47%-15.80%
HK:1877HK:187741NeutralHKD 30.07B-69.15-7.23%―35.82%54.40%

* Healthcare Sector Average

Performance Comparison

-40%-20%0%20%HK:6160HK:1801HK:9926HK:9995HK:1877HK:2696Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
HK:6160 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
HK:6160BeOne Medicines Ltd221.4033.8018.02%
HK:1801Innovent Biologics79.75-10.45-11.59%
HK:9926Akeso, Inc.81.50-36.80-31.11%
HK:9995RemeGen Co. Ltd. Class H64.85-28.00-30.16%
HK:1877Shanghai Junshi Biosciences Co., Ltd. Class H15.26-11.44-42.85%
HK:2696Shanghai Henlius Biotech, Inc. Class H49.06-20.04-29.00%

BeOne Medicines Ltd Corporate Events

BeOne Medicines Grants RSUs to 235 Employees Under Incentive Plan

Sep 4, 2026

BeOne Medicines Ltd. has granted 28,949 restricted share units, equivalent to 376,337 underlying shares or about 0.02% of its issued share capital, to 235 employees under its 2016 Share Option and Incentive Plan. The RSUs will vest over four years on...

BeOne Medicines’ Interim Profit Soars on Double-Digit Revenue Growth

Aug 26, 2026

BeOne Medicines reported a strong interim performance for the six months ended June 30, 2026, with total revenues climbing 32.3% year-on-year to US$3.22 billion, driven mainly by a 31.4% increase in product revenue to US$3.17 billion. Despite a 14.9%...

BeOne Medicines Sets Audit Committee Review for Dual-Market Interim Results

Aug 14, 2026

BeOne Medicines Ltd, a Swiss-incorporated biopharmaceutical company listed on the Hong Kong Stock Exchange, focuses on developing medicines for international markets and maintains dual financial reporting in the U.S. and Hong Kong. Its board, led by...

BeOne Medicines Grants New RSUs to Staff and Service Provider Under Incentive Plan

Aug 13, 2026

BeOne Medicines Ltd, a Swiss-incorporated biopharmaceutical company listed on the Hong Kong Stock Exchange, develops medicines in its core therapeutic areas and supplements its commercial strategy with unbranded disease awareness initiatives. The com...

BeOne Medicines Files Latest U.S. Form 10-Q, Highlights Global Shareholder Base

Aug 5, 2026

BeOne Medicines Ltd., a Swiss-incorporated drug developer with listings in Hong Kong, Shanghai and on Nasdaq via ADSs, has confirmed that it remains a large accelerated filer under U.S. securities rules and is not classified as an emerging growth or...

BeOne Medicines Posts Unaudited Q2 2026 Results and Cautions on Preliminary Guidance

Aug 5, 2026

BeOne Medicines Ltd, a Switzerland-incorporated oncology-focused biopharmaceutical group listed in Hong Kong, has reported unaudited condensed consolidated financial results for the three and six months ended June 30, 2026, prepared under U.S. GAAP....

BeOne Medicines Issues New Shares to Fund Employee Stock Purchase Plan

Jul 30, 2026

BeOne Medicines has approved the issuance of 866,073 new shares to its wholly owned subsidiary BGNC2, to be re-transferred and held for the benefit of approximately 4,694 eligible employees participating in its 2018 Employee Stock Purchase Plan. The...

BeOne Medicines Sets August Timetable for Q2 and Interim 2026 Results

Jul 17, 2026

BeOne Medicines Ltd said it will publish its unaudited second-quarter 2026 financial results, prepared under U.S. GAAP and SEC rules, after Hong Kong trading hours on August 5, 2026, following review and approval by its audit committee. Management wi...

BeOne Medicines Grants New RSUs to 215 Employees Under 2016 Incentive Plan

Jul 8, 2026

BeOne Medicines Ltd has granted 33,388 restricted share units in the form of ADSs to 215 employees under its 2016 Share Option and Incentive Plan, representing 434,044 underlying shares or about 0.03% of its issued share capital. The awards carry no...

BeOne Medicines’ BRUKINSA Delivers Pivotal Phase 3 Win in Frontline Mantle Cell Lymphoma

Jun 30, 2026

BeOne Medicines reported positive topline Phase 3 results from its global MANGROVE trial, which tested BTK inhibitor BRUKINSA plus rituximab against standard bendamustine plus rituximab in previously untreated mantle cell lymphoma. The study met its...

BeOne Medicines Faces RMB446 Million Tax Payment in China, Sees No Material Impact

Jun 26, 2026

BeOne Medicines Ltd.’s wholly owned Chinese subsidiary has agreed with local tax authorities to adjust previously filed tax returns, resulting in an upcoming income tax and surcharge payment of about RMB446 million. The company stated that ther...

BeOne Medicines Grants New Equity Awards Under 2016 Incentive Plan

Jun 18, 2026

BeOne Medicines has granted new equity awards under its 2016 Share Option and Incentive Plan, issuing options over 94,068 American depositary shares to six grantees, including two directors. The company also granted 1,499,134 restricted share units t...

BeOne Medicines Files U.S. Form S-8 to Expand Equity Incentive Plans

Jun 11, 2026

BeOne Medicines Ltd., a Swiss-incorporated biopharmaceutical company listed in Hong Kong, has filed a Form S-8 registration statement with the U.S. Securities and Exchange Commission. The filing covers shares issuable under its Fifth Amended and Rest...

BeOne Medicines Shareholders Approve All AGM Resolutions and Refresh Board

Jun 11, 2026

BeOne Medicines Ltd reported that all resolutions proposed at its 2026 annual general meeting were duly passed by shareholders, including approval of the audited 2025 Swiss statutory standalone and consolidated financial statements and the appropriat...

BeOne Medicines Sets Out Board and Committee Structure to Bolster Governance

Jun 11, 2026

BeOne Medicines has detailed the composition of its board of directors and the allocation of responsibilities across five key board committees, underscoring a robust corporate governance framework. The company has appointed Chairman and CEO John V. O...

BeOne Medicines Secures Multiple HKEX Rule Waivers to Support Flexible Financing and Partnerships

Jun 11, 2026

BeOne Medicines has published an updated company information sheet dated 11 June 2026 outlining a series of waivers and exemptions it has obtained from strict compliance with various Hong Kong Stock Exchange Listing Rules and related ordinances. The...

BeOne Medicines Formalizes Compensation Committee Charter to Strengthen Governance

Jun 11, 2026

BeOne Medicines Ltd. has formalized the role and responsibilities of its Compensation Committee, which is tasked with overseeing compensation for directors and executive officers, as well as the company’s broader talent management and successio...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Aug 09, 2026