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2257 Stock Chart & Stats
HK$4.00
HK$0.00(0.00%)
At close: 4:00 PM EDT
HK$4.00
HK$0.00(0.00%)
Day’s Range― - ―
52-Week RangeHK$3.67 - HK$22.78
Previous CloseN/A
Volume54.85K
Average Volume (3M)442.62K
Market Cap
HK$434.50M
Enterprise ValueHK$65.29M
Total Cash (Recent Filing)HK$13.52M
Total Debt (Recent Filing)HK$9.31M
Price to Earnings (P/E)―
Beta1.30
Next Earnings
Aug 27, 2026EPS EstimateN/A
Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-0.15
Shares Outstanding109,721,535
10 Day Avg. Volume408,789
30 Day Avg. Volume442,620
Financial Highlights & Ratios
PEG Ratio0.09
Price to Book (P/B)-9.39
Price to Sales (P/S)0.00
P/FCF Ratio-10.06
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)N/A
Revenue Forecast (FY)HK$162.00M
Bulls Say, Bears Say
Bulls Say
Specialized RNAi PlatformSirnaomics’ explicit focus on siRNA therapeutics and related delivery technologies represents a durable strategic niche. RNAi is a high-barrier, science-driven area where successful delivery and target validation create sustainable competitive advantage and long-term licensing or partnership optionality if clinical progress continues.
Improving Cash Burn TrendA sustained reduction in cash burn over two consecutive years indicates management has taken lasting steps to tighten spending or prioritize programs. Even though cash flow remains negative, a multi-year improvement trend extends runway and reduces near-term refinancing pressure, supporting continuity of R&D activities through 2–6 months and beyond.
Reduced Net Loss In 2025A materially smaller net loss indicates better cost control or program prioritization, a durable operational improvement. If maintained, this reduces reliance on immediate external funding, lowers dilution risk, and improves ability to allocate scarce capital toward late-stage or higher-value programs over the medium term.
Bears Say
Negative Shareholder EquityNegative equity is a structural balance-sheet impairment that undermines borrowing capacity and creditor confidence. It heightens refinancing and dilution risk, constrains strategic flexibility, and can materially limit the company’s ability to fund expensive clinical development without significant external capital or strategic partnerships.
Revenue Base CollapsedA collapse to zero revenue removes any commercial cushion and leaves the company fully dependent on financing or partnerships. Over the medium term this weakens validation of underlying programs, increases execution risk, and means long-term viability depends on successful clinical advances or non-dilutive licensing deals.
Persistent Negative Operating Cash FlowChronic negative operating and free cash flow is a structural problem for an R&D biotech: it requires repeated external financing, raises dilution risk, and limits the company's ability to fund larger, costlier trials. Without durable positive cash generation or secured partnerships, growth and program advancement are constrained.
Sirnaomics Ltd. News
2257 FAQ
What was Sirnaomics Ltd.’s price range in the past 12 months?
Sirnaomics Ltd. lowest stock price was HK$3.67 and its highest was HK$22.78 in the past 12 months.
What is Sirnaomics Ltd.’s market cap?
Sirnaomics Ltd.’s market cap is HK$434.50M.
When is Sirnaomics Ltd.’s upcoming earnings report date?
Sirnaomics Ltd.’s upcoming earnings report date is Aug 27, 2026 which is in 20 days.
How were Sirnaomics Ltd.’s earnings last quarter?
Sirnaomics Ltd. released its earnings results on Mar 27, 2026. The company reported -HK$0.881 earnings per share for the quarter, missing the consensus estimate of N/A by -HK$0.881.
Is Sirnaomics Ltd. overvalued?
According to Wall Street analysts Sirnaomics Ltd.’s price is currently Overvalued.
Does Sirnaomics Ltd. pay dividends?
Sirnaomics Ltd. does not currently pay dividends.
What is Sirnaomics Ltd.’s EPS estimate?
Sirnaomics Ltd.’s EPS estimate for its next earnings report is not yet available.
How many shares outstanding does Sirnaomics Ltd. have?
Sirnaomics Ltd. has 109,721,535 shares outstanding.
What happened to Sirnaomics Ltd.’s price movement after its last earnings report?
Sirnaomics Ltd. reported an EPS of -HK$0.881 in its last earnings report, missing expectations of N/A. Following the earnings report the stock price went up 5.516%.
Which hedge fund is a major shareholder of Sirnaomics Ltd.?
Currently, no hedge funds are holding shares in HK:2257
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Sirnaomics Ltd. Stock Smart Score
Neutral
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10
Technicals
SMA
Positive
20 days / 200 days
Momentum
207.69%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
-27.12%
Trailing 12-Months
Company Description
Sirnaomics Ltd.
Sirnaomics Ltd. is an RNA therapeutics biopharmaceutical company, founded in 2007 and headquartered in Gaithersburg, Maryland. The company is dedicated to identifying and developing innovative therapeutic compounds aimed at addressing significant medical needs across the United States and the People's Republic of China. Its leading pipeline assets include STP705, which is being investigated for conditions such as cutaneous squamous cell carcinoma in situ, basal cell carcinoma, various liver-related cancers (cholangiocarcinoma, hepatocellular carcinoma, liver metastases), as well as for keloid scar remodeling, hypertrophic scarring, and fat sculpting. Another prominent candidate, STP707, is designed to treat cholangiocarcinoma, hepatocellular carcinoma, liver metastases, metastatic cutaneous squamous cell carcinoma, non-small cell lung cancer, and both liver and lung fibrosis. Beyond these lead programs, Sirnaomics is advancing STP355 for a range of cancers; STP369 for head and neck/bladder cancers; STP779 for liver, lung, and pancreatic cancers; and STP902 for breast cancer. The company's portfolio also extends to infectious diseases with STP702 for influenza, STP908 for COVID-19, the RIM730 COVID-19 vaccine, and STP909 for HPV/cervical cancer. Furthermore, its developmental pipeline encompasses STP122G for thrombotic disorders, STP125G for hypertriglyceridemia, STP144G for complement-mediated ailments, STP133G for cardiometabolic conditions, and STP155G for hepatitis B virus.
Technical Analysis
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