Lepu Biopharma Co. Ltd. Class H stock analysis
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Lepu Biopharma Co. Ltd. Class H (2157) Stock Price & Analysis
2157 Stock Chart & Stats
- Day’s Range
- HKD 2.85 - HKD 2.96
- 52-Week Range
- HKD 2.77 - HKD 6.65
- Previous Close
- HKD 2.96
- Volume
- N/A
- Average Volume (3M)
- 11.20M
- Market Cap
- HKD 5.34B
- Enterprise Value
- HKD 7.44B
- Total Cash (Recent Filing)
- HKD 788.84M
- Total Debt (Recent Filing)
- HKD 1.18B
- Price to Earnings (P/E)
- 18.4
- Beta
- 0.55
- Next Earnings
- Mar 31, 2027 (Est.)
- EPS Estimate
- N/A
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Revenue And Profit Inflection
The 2025 revenue surge and shift to a sizable profit indicate that Lepu Biopharma has achieved meaningful commercial scale after earlier development-stage losses. If this operating inflection persists, it can strengthen internal funding capacity and support continued investment in oncology growth.
High Gross Margins
Sustained gross margins above 80% point to attractive economics on the company’s marketed or partnered products and provide substantial room to absorb operating costs. This margin structure can support reinvestment in research, commercialization, and pipeline expansion if revenue remains durable.
Improving Equity Returns
The return to positive ROE suggests that the 2025 earnings improvement translated into more productive use of shareholder capital. Combined with equity expansion and a lower debt-to-equity ratio than in 2024, this indicates improving financial efficiency and a stronger base for future growth.
Bears Say
Negative Cash Conversion
Negative operating and free cash flow while reporting a sizable profit shows that earnings are not yet converting reliably into liquidity. Continued cash deficits could require external funding, constrain research and commercialization spending, and increase financial risk during the next development cycle.
Meaningful Debt Load
Although the debt-to-equity ratio improved as equity expanded, the absolute increase in total debt leaves the company exposed to financing obligations. A meaningful debt burden can reduce flexibility to fund pipeline opportunities and create greater pressure if earnings or cash generation weaken.
Unproven Turnaround Durability
The sharp 2025 improvement follows several years of substantial losses and limited earlier revenue, so the current earnings level has not yet been established as a stable multi-year trend. This history raises execution risk around sustaining commercialization, margins, and profitability.
Lepu Biopharma Co. Ltd. Class H News
Lepu Biopharma Posts Strong Clinical Data Across Key Oncology ADC Programs
An announcement from Lepu Biopharma Co. Ltd. Class H ( ($HK:2157) ) is now available. Lepu Biopharma reported positive Phase III results for its CLDN18.2-targeting antibody-drug conjugate CMG901 (sonesitatug vedotin),
Lepu Biopharma Schedules Board Meeting to Review 2026 Interim Results and Potential Dividend
Lepu Biopharma Co. Ltd. Class H ( ($HK:2157) ) has provided an update. Lepu Biopharma Co., Ltd., a Hong Kong-listed Chinese biopharmaceutical company, has a board that includes executive, non-executive
Lepu Biopharma’s Claudin 18.2 ADC CMG901 Delivers Positive Global Phase III Gastric Cancer Data
Lepu Biopharma Co. Ltd. Class H ( ($HK:2157) ) has provided an announcement. Lepu Biopharma reported that its Claudin 18.2-targeting antibody-drug conjugate CMG901, licensed globally to AstraZeneca, achieved positive top-line
2157 FAQ
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Lepu Biopharma Co. Ltd. Class H Stock Smart Score
Company Description
Lepu Biopharma Co. Ltd. Class H
Lepu Biopharma Co., Ltd. operates as a biopharmaceutical enterprise, concentrating its efforts on the development of innovative oncology therapies. It maintains a broad pipeline of cancer-fighting products primarily aimed at the Chinese market. The company's therapeutic candidates encompass a range of modalities, including cutting-edge antibody-drug conjugates (ADCs), oncolytic virus treatments, and diverse immunotherapies. Among its immuno-oncology offerings are HX008 (an anti-PD-1 mAb) and LP002 (an anti-PD-L1 mAb). The ADC portfolio features MRG003 (targeting EGFR), MRG002 (targeting HER2), MRG001 (targeting CD20), MRG004A (targeting TF), and CMG901 (targeting CLDN18.2). Additionally, Lepu Biopharma is advancing the oncolytic virus CG0070, along with various combination therapies such as HX008+OH2, LP002+OH2, and HX008+LP002. Founded in 2018, the company is headquartered in Shanghai, China.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Sui Ziye
- Employees
- 646
- Website
- www.lepubiopharma.com
- Address
- Block 4, Shanghai, SH, 201612, CN
Lepu Biopharma Co. Ltd. Class H (2157) Earnings & Revenues
2157 Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 3 | 5 | 14 |
| Technical Analysis | 3 | 5 | 2 |
| Moving Averages | 0 | 0 | 12 |











