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Ascletis Pharma, Inc. (HK:1672)
:1672
Hong Kong Market
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Ascletis Pharma, Inc. (1672) AI Stock Analysis

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HK:1672

Ascletis Pharma, Inc.

(1672)

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Neutral 46 (OpenAI - 4o)
Rating:46Neutral
Price Target:
HK$10.50
▼(-1.69% Downside)
Ascletis Pharma's overall stock score is primarily impacted by its financial performance and technical analysis. The company's strong balance sheet and cash reserves are positive, but ongoing financial losses and weak market momentum present significant risks. The negative P/E ratio and lack of dividend yield further reflect the company's current challenges in achieving profitability.

Ascletis Pharma, Inc. (1672) vs. iShares MSCI Hong Kong ETF (EWH)

Ascletis Pharma, Inc. Business Overview & Revenue Model

Company DescriptionAscletis Pharma Inc., a biotechnology company, engages in the research and development, manufacture, marketing, and sale of pharmaceutical products in Mainland China and internationally. The company offers Ritonavir oral tablet, a pharmacokinetic booster of various oral antiviral drugs targeting viral proteases and a component of the approved oral antiviral drug Paxlovid; ASCLEVIR and GANOVO for the treatment of Hepatitis C virus. It is also developing ASC22 for treating chronic hepatitis B (CHB) and human immunodeficiency virus functional cure; ASC42 for chronic hepatitis B functional cure; ASC10 and ASC11 to treat COVID-19; ASC40, ASC41, ASC42, ASC43F FDC, ASC44F FDC, and ASC45F FDC for non-alcoholic steatohepatitis; and ASC42 for the treatment of primary biliary cholangitis. In addition, the company is developing ASC40 to treat recurrent glioblastoma, drug resistant breast cancer, and KRAS mutant non-small cell lung cancer; ASC61 and ASC63 for advanced solid tumors; ASC60 to treat solid tumors; and ASC40 for the treatment of acne, Ascletis Pharma Inc. was founded in 2013 and is headquartered in Hangzhou, the People's Republic of China.
How the Company Makes MoneyAscletis Pharma, Inc. generates revenue primarily through the sale of pharmaceutical products across its key therapeutic areas. The company invests heavily in research and development to bring new drugs to market and collaborates with various partners to enhance its product offerings and expand its market reach. Revenue streams also include licensing agreements, where the company licenses its proprietary technologies and drug candidates to other pharmaceutical companies. Additionally, Ascletis may receive milestone payments and royalties as part of these collaborations and licensing deals, further contributing to its earnings.

Ascletis Pharma, Inc. Financial Statement Overview

Summary
Ascletis Pharma's financial performance is mixed. The income statement reveals ongoing operational struggles with negative net profit and EBIT margins, leading to a low score. However, the balance sheet is strong with a high equity ratio and low debt levels, contributing positively. Cash flow generation remains a concern with negative operating and free cash flow, reflecting potential future liquidity issues.
Income Statement
35
Negative
Ascletis Pharma's income statement reveals significant challenges in terms of profitability. The company has a negative net profit margin and EBIT margin, indicating ongoing operational and financial struggles. Despite an increase in total revenue in 2024, the company continues to incur substantial losses, and the revenue growth has been inconsistent over the years. The biotechnology industry often requires high R&D investments, which could explain the persistent negative earnings, but it poses a risk if this trend continues.
Balance Sheet
70
Positive
The balance sheet of Ascletis Pharma shows a strong equity base, with a high equity ratio indicating stability. The company has maintained a low level of debt relative to equity, which is a positive sign of financial prudence. However, the persistent net losses have not yet impacted the equity base severely. The company's large cash reserves provide a buffer against operational losses, though continued losses could eventually erode this financial cushion.
Cash Flow
40
Negative
The cash flow statements highlight a concerning lack of positive cash flow generation. Ascletis Pharma has struggled to generate operating cash flow, and free cash flow remains negative, indicating the company's difficulty in achieving self-sustaining operations. While cash reserves remain robust, the lack of cash flow from core operations suggests potential liquidity issues if the trend continues without improvements in operational efficiency or revenue generation.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.28M56.60M54.09M76.88M35.00M
Gross Profit735.00K25.99M-24.69M39.17M-23.50M
EBITDA-390.58M-126.09M-284.50M-169.35M-181.94M
Net Income-300.94M-144.72M-366.71M-202.14M-262.05M
Balance Sheet
Total Assets2.12B2.49B2.66B2.83B3.07B
Cash, Cash Equivalents and Short-Term Investments1.95B2.30B2.48B2.50B2.71B
Total Debt7.63M8.42M4.24M2.75M1.59M
Total Liabilities158.41M148.94M117.16M100.89M85.42M
Stockholders Equity1.97B2.34B2.54B2.73B2.98B
Cash Flow
Free Cash Flow-343.73M-163.32M-156.85M-154.13M-123.87M
Operating Cash Flow-341.58M-144.16M-142.45M-146.93M-84.91M
Investing Cash Flow978.91M149.84M-1.30B-274.49M132.30M
Financing Cash Flow-103.51M-81.50M-1.42M-31.10M-21.67M

Ascletis Pharma, Inc. Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price10.68
Price Trends
50DMA
12.54
Negative
100DMA
10.23
Positive
200DMA
7.57
Positive
Market Momentum
MACD
-0.65
Positive
RSI
40.08
Neutral
STOCH
10.20
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:1672, the sentiment is Neutral. The current price of 10.68 is below the 20-day moving average (MA) of 12.74, below the 50-day MA of 12.54, and above the 200-day MA of 7.57, indicating a neutral trend. The MACD of -0.65 indicates Positive momentum. The RSI at 40.08 is Neutral, neither overbought nor oversold. The STOCH value of 10.20 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for HK:1672.

Ascletis Pharma, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
42.18B47.3927.23%2.57%18.79%
57
Neutral
14.22B-67.94-58.53%240.05%-140.09%
53
Neutral
12.13B-21.180.00%1219.19%25.15%
46
Neutral
HK$10.67B-12.74%-76.58%-4.90%
41
Neutral
3.64B-5.16-106.25%0.00%-18.99%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:1672
Ascletis Pharma, Inc.
10.68
9.68
968.00%
HK:2157
Lepu Biopharma Co. Ltd. Class H
7.65
4.70
159.32%
HK:2171
CARsgen Therapeutics Holdings Ltd.
21.06
17.91
568.57%
HK:2179
Jiangsu Recbio Technology Co., Ltd. Class H
7.60
-1.30
-14.61%
HK:2696
Shanghai Henlius Biotech, Inc. Class H
77.65
54.65
237.61%
HK:6955
Shandong Boan Biotechnology Company., Limited. Class H
13.97
4.78
52.01%

Ascletis Pharma, Inc. Corporate Events

Ascletis Pharma’s Controlling Shareholders Commit to Share Lock-Up Amid Clinical Trials
Sep 11, 2025

Ascletis Pharma Inc. announced a voluntary lock-up undertaking by its controlling shareholders, Dr. Jinzi Jason Wu and Mrs. Judy Hejingdao Wu, who have committed not to dispose of their shares until the completion of key clinical studies. This move reflects their confidence in the company’s long-term prospects and aims to reassure investors about the company’s future developments in obesity treatment. The lock-up involves 575,952,078 shares, representing approximately 58.03% of the company’s total shares, and is linked to the outcomes of clinical trials expected by the end of 2025.

The most recent analyst rating on (HK:1672) stock is a Buy with a HK$32.00 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma’s ASC30 Shows Promise in Obesity Management
Sep 9, 2025

Ascletis Pharma Inc. has announced the successful demonstration of an ultra-long-acting subcutaneous depot maintenance formulation of its small molecule GLP-1 receptor agonist, ASC30, which showed a 75-day observed half-life in a U.S. Phase Ib study involving participants with obesity. This advancement supports once-quarterly administration, addressing a significant unmet need for maintenance therapy in chronic weight management. The formulation demonstrated favorable tolerability with minimal gastrointestinal side effects, potentially enhancing patient compliance and quality of life.

The most recent analyst rating on (HK:1672) stock is a Buy with a HK$32.00 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma to Present Promising ASC30 Study Results at EASD Meeting
Sep 2, 2025

Ascletis Pharma Inc. announced that it will present the results of its 28-day multiple ascending dose study of ASC30, an oral small molecule GLP-1 receptor agonist, at the European Association for the Study of Diabetes Annual Meeting in Vienna. The study demonstrated superior weight loss in participants with obesity, positioning ASC30 as a potentially differentiated treatment option. The company is on track to report topline data from a Phase IIa clinical study in the fourth quarter of 2025, which could enhance its market position in obesity treatment.

The most recent analyst rating on (HK:1672) stock is a Buy with a HK$32.00 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Reports Promising Phase Ib Results for ASC30 in Obesity Treatment
Aug 27, 2025

Ascletis Pharma Inc. announced promising results from its U.S. Phase Ib study of the ASC30 oral once-daily tablet, which showed significantly higher drug exposure compared to orforglipron, a competing treatment. This higher exposure is linked to greater weight loss in participants with obesity, positioning ASC30 as a potentially competitive treatment. The study also highlighted ASC30’s favorable safety and tolerability profile, with no serious adverse events reported, suggesting its potential as a differentiated option in the obesity treatment market.

The most recent analyst rating on (HK:1672) stock is a Buy with a HK$32.00 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Completes Share Placing and Subscription to Boost R&D
Aug 25, 2025

Ascletis Pharma, Inc. announced the completion of a placing and subscription of shares, raising approximately HK$467.69 million in net proceeds. The funds are primarily earmarked for advancing the company’s drug candidates into clinical trials for obesity, with a small portion allocated for general corporate purposes. This strategic move is expected to bolster Ascletis Pharma’s R&D capabilities and strengthen its market position.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$14.75 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Announces Share Placing and Subscription to Fund R&D
Aug 18, 2025

Ascletis Pharma, Inc. announced a placing and top-up subscription agreement involving the sale of 52,400,000 existing shares and the issuance of 28,820,000 new shares. The transaction is expected to raise approximately HK$467.69 million in net proceeds, which will be primarily used for advancing clinical trials for obesity treatments and general corporate purposes. This strategic move is aimed at strengthening the company’s financial position and supporting its R&D initiatives, although it will result in a slight reduction of the controlling shareholders’ stake in the company.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma’s Obesity Drug Candidates Show Promising Preclinical Results
Aug 18, 2025

Ascletis Pharma Inc. announced promising preclinical results for its obesity treatment drug candidates, ASC47 and ASC31, demonstrating significant weight loss in an animal model. The combination of these drugs showed a 44.8% reduction in body weight, outperforming a similar combination with tirzepatide, indicating potential differentiation in the obesity treatment market.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Reports Reduced Losses and R&D Progress in Interim Results
Aug 15, 2025

Ascletis Pharma Inc. announced its unaudited interim results for the six months ending June 30, 2025, highlighting a significant reduction in losses by 32.5% compared to the previous year, despite increased R&D costs. The company made notable progress in its metabolic disease pipeline, including advancements in obesity and acne treatments, underscoring its strong R&D capabilities and commitment to addressing unmet clinical needs. Ascletis has sufficient cash reserves to support its operations and research activities until 2029.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 19, 2025