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CANbridge Pharmaceuticals Inc. (HK:1228)
:1228
Hong Kong Market
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CANbridge Pharmaceuticals Inc. (1228) AI Stock Analysis

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HK:1228

CANbridge Pharmaceuticals Inc.

(1228)

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Underperform 40 (OpenAI - 4o)
Rating:40Underperform
Price Target:
HK$2.00
▲(1.52% Upside)
CANbridge Pharmaceuticals Inc. is facing significant financial challenges, with high operational losses and negative equity being the most impactful factors. The technical analysis indicates a bearish trend, and the valuation is unattractive due to a negative P/E ratio and lack of dividends. These factors collectively contribute to a low overall stock score.

CANbridge Pharmaceuticals Inc. (1228) vs. iShares MSCI Hong Kong ETF (EWH)

CANbridge Pharmaceuticals Inc. Business Overview & Revenue Model

Company DescriptionCANbridge Pharmaceuticals Inc., a biopharmaceutical company, engages in the research, development, and commercialization of therapies for rare diseases and oncology indications worldwide. The company offers Hunterase, an enzyme replacement therapy for the treatment of Hunter syndrome; NERLYNX (Neratinlib), a potent irreversible tyrosine kinase inhibitor for HER2-positive breast cancer; and Caphosol Mouth Rinse for temporary and persistent dryness of the mouth and throat. It also engages in the development of CAN008, an artificially engineered antibody-like fully human fusion protein for the treatment of glioblastoma multiforme; CAN108, an orally absorbed reversible inhibitor of the ileal bile acid transporter to treat rare cholestatic liver diseases; CAN106, a humanized monoclonal antibody against complement C5 being developed for the treatment of complement-mediated diseases; CAN103, a recombinant human enzyme replacement therapy (ERT); CAN104, a recombinant human ERT; CAN105, a bispecific antibody; CAN201, a gene therapy program that utilizes adeno-associated virus (AAV) sL65 capsid; and CAN202, a gene therapy program utilizing AAV sL65 capsid. The company was founded in 2012 and is headquartered in Beijing, China.
How the Company Makes MoneyCANbridge Pharmaceuticals Inc. generates revenue through the commercialization of its proprietary and in-licensed pharmaceutical products. The company's revenue streams include sales of its marketed therapies in the rare disease and oncology sectors, as well as potential royalties and milestone payments from partnerships. CANbridge also engages in strategic collaborations and licensing agreements with other biotech companies, which may contribute to its revenue through shared profits and co-development opportunities. Additionally, government grants and research funding might play a role in supporting its development programs.

CANbridge Pharmaceuticals Inc. Financial Statement Overview

Summary
CANbridge Pharmaceuticals Inc. faces significant financial hurdles with high operational losses and negative equity. The company's ongoing cash flow struggles and reliance on financing highlight the challenges in achieving financial sustainability. Strategic changes are needed to improve profitability and financial health in the highly competitive biotechnology sector.
Income Statement
45
Neutral
The company shows a declining revenue trend with significant net losses. Gross profit margins are positive but are overshadowed by high negative EBIT and net profit margins due to substantial expenditures. Revenue growth has been inconsistent, demonstrating challenges in achieving sustainable growth in a competitive industry.
Balance Sheet
30
Negative
The company's balance sheet reflects high leverage with negative equity, indicating financial instability. The debt-to-equity ratio cannot be calculated due to negative equity, which poses a risk in volatile markets. Despite a relatively low asset base, the company struggles with substantial liabilities, indicating potential liquidity issues.
Cash Flow
40
Negative
Operating and free cash flows are consistently negative, indicating challenges in generating positive cash flow from operations. The company's reliance on external financing is evident, and the cash flow to net income ratios highlight inefficiencies in converting profits into cash, exacerbating financial strain.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue62.56M85.10M102.87M78.97M31.16M12.03M
Gross Profit40.29M54.30M64.16M48.89M18.78M6.88M
EBITDA-150.16M-328.69M-341.43M-454.63M-1.06B-824.41M
Net Income-136.11M-442.62M-378.84M-483.48M-1.08B-846.04M
Balance Sheet
Total Assets105.50M116.81M395.36M702.04M892.52M586.36M
Cash, Cash Equivalents and Short-Term Investments1.96M10.50M137.49M451.16M745.82M360.80M
Total Debt34.97M135.78M141.93M155.28M52.10M46.90M
Total Liabilities514.58M591.30M435.15M393.49M199.13M2.33B
Stockholders Equity-409.08M-474.49M-39.79M308.56M693.39M-1.75B
Cash Flow
Free Cash Flow-14.19M-122.50M-319.09M-315.76M-592.40M-305.13M
Operating Cash Flow-14.10M-122.39M-278.23M-280.98M-587.07M-151.65M
Investing Cash Flow-38.00K13.93M-26.86M-34.79M126.09M-153.48M
Financing Cash Flow0.00-18.57M-28.02M-20.70M854.31M679.26M

CANbridge Pharmaceuticals Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.97
Price Trends
50DMA
2.43
Negative
100DMA
1.61
Positive
200DMA
0.88
Positive
Market Momentum
MACD
-0.12
Positive
RSI
40.29
Neutral
STOCH
39.79
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:1228, the sentiment is Negative. The current price of 1.97 is below the 20-day moving average (MA) of 2.31, below the 50-day MA of 2.43, and above the 200-day MA of 0.88, indicating a neutral trend. The MACD of -0.12 indicates Positive momentum. The RSI at 40.29 is Neutral, neither overbought nor oversold. The STOCH value of 39.79 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:1228.

CANbridge Pharmaceuticals Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$7.86B-0.30-43.30%2.27%22.53%-2.21%
HK$2.67B-2.5779.98%-3.40%
HK$1.05B83.89%
HK$939.92M-5.27-40.24%66.43%
HK$1.35B-4.32-34.18%-57.84%24.58%
HK$1.57B-51.56%2.45%2.58%
HK$921.92M-54.87%81.67%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:1228
CANbridge Pharmaceuticals Inc.
1.98
1.72
661.54%
HK:9939
Kintor Pharmaceutical Ltd
1.88
0.78
70.91%
HK:2126
JW (Cayman) Therapeutics Co. Ltd.
3.48
2.05
143.36%
HK:2197
Clover Biopharmaceuticals Ltd.
2.24
1.93
622.58%
HK:2257
Sirnaomics Ltd.
9.77
6.78
226.76%
HK:6628
Transcenta Holding Limited
3.05
2.04
201.98%

CANbridge Pharmaceuticals Inc. Corporate Events

CANbridge Pharmaceuticals Completes HK$22.59 Million Share Subscription
Sep 28, 2025

CANbridge Pharmaceuticals Inc. has successfully completed the subscription of new shares under a general mandate, issuing nearly 10 million shares at a price of HK$2.26 each, generating gross proceeds of approximately HK$22.59 million. This strategic move, involving independent subscribers, is expected to bolster the company’s financial position and support its operational plans, enhancing its market presence and potentially benefiting stakeholders by expanding its capital base.

The most recent analyst rating on (HK:1228) stock is a Hold with a HK$2.00 price target. To see the full list of analyst forecasts on CANbridge Pharmaceuticals Inc. stock, see the HK:1228 Stock Forecast page.

CANbridge Pharmaceuticals to Raise HK$22.59 Million Through New Share Subscriptions
Sep 15, 2025

CANbridge Pharmaceuticals Inc. has entered into three subscription agreements to issue nearly 10 million new shares at a discounted price of HK$2.26 each, raising gross proceeds of approximately HK$22.59 million. The net proceeds will be used for research and development of existing products and daily operations, potentially strengthening the company’s financial position and enhancing its ability to innovate in the biopharmaceutical industry.

The most recent analyst rating on (HK:1228) stock is a Hold with a HK$2.00 price target. To see the full list of analyst forecasts on CANbridge Pharmaceuticals Inc. stock, see the HK:1228 Stock Forecast page.

CANbridge Pharmaceuticals Details Write-Off and Share Scheme Updates
Sep 3, 2025

CANbridge Pharmaceuticals Inc. has announced additional details regarding the write-off of its right of use assets related to its office and laboratory in Boston, U.S., as part of its downsizing efforts. The lease liabilities remained recognized in the financial statements as of December 31, 2024, due to the lease contract’s legal binding until February 28, 2025. Additionally, the company provided updates on its share schemes, detailing the exercise of options and vesting of RSUs under its Pre-IPO Equity Incentive Plan and Post-IPO RSU Scheme, reflecting ongoing employee incentives and stock management strategies.

The most recent analyst rating on (HK:1228) stock is a Hold with a HK$2.00 price target. To see the full list of analyst forecasts on CANbridge Pharmaceuticals Inc. stock, see the HK:1228 Stock Forecast page.

CANbridge Pharmaceuticals Reports Major Milestones in Drug Development and Strategic Partnerships
Aug 31, 2025

CANbridge Pharmaceuticals Inc. announced significant progress in its drug pipeline and business operations for the first half of 2025. The company has entered a strategic cooperation with Baheal Medical, enhancing its marketing and distribution capabilities in China, Hong Kong, and Macau. Key product developments include the commercial launch and expanded insurance coverage for Hunterase® and Livmarli®, as well as the marketing approval for Gaurunning®, a new drug for Gaucher Disease. Additionally, CANbridge is advancing its gene therapy program for Duchenne Muscular Dystrophy, having licensed new technology and generated pre-clinical proof-of-concept data.

The most recent analyst rating on (HK:1228) stock is a Hold with a HK$2.00 price target. To see the full list of analyst forecasts on CANbridge Pharmaceuticals Inc. stock, see the HK:1228 Stock Forecast page.

CANbridge Pharmaceuticals Completes Share Subscription and Strengthens Strategic Partnerships
Aug 27, 2025

CANbridge Pharmaceuticals Inc. has completed the subscription of new shares under a general mandate, raising gross proceeds of HKD100,461,767.12. This financial move is part of a strategic cooperation agreement with Baheal Zhihe, which will act as the exclusive marketing service provider for CANbridge’s products in designated regions. Additionally, the company has appointed Mr. Wang Tingwei as a non-executive director and a member of the Nomination Committee, further strengthening its corporate governance structure.

The most recent analyst rating on (HK:1228) stock is a Hold with a HK$2.00 price target. To see the full list of analyst forecasts on CANbridge Pharmaceuticals Inc. stock, see the HK:1228 Stock Forecast page.

CANbridge Pharmaceuticals to Review Interim Financial Results
Aug 19, 2025

CANbridge Pharmaceuticals Inc. has announced that its Board of Directors will convene on August 29, 2025, to review and approve the company’s unaudited interim results for the first half of the year. This meeting is significant as it will provide insights into the company’s financial health and operational progress, potentially impacting investor confidence and stakeholder engagement.

CANbridge Pharmaceuticals Enhances Market Reach with Baheal Partnership
Aug 12, 2025

CANbridge Pharmaceuticals Inc. has entered into a strategic collaboration and exclusive commercial services agreement with a subsidiary of Qingdao Baheal Medical Inc. This agreement appoints Baheal as the exclusive Contract Sales Organization for promoting CANbridge’s products in mainland China, Hong Kong, and Macau. The agreement, which is of a revenue nature and part of the company’s ordinary business activities, does not constitute a notifiable or connected transaction under Hong Kong’s listing rules. This strategic move is expected to enhance CANbridge’s market presence in the Greater China region.

CANbridge Pharmaceuticals Announces New Share Subscription Agreement
Aug 12, 2025

CANbridge Pharmaceuticals Inc. has entered into a Subscription Agreement to issue 74,971,468 new shares at a price of HK$1.34 per share, representing a discount to the last trading day’s closing price but a premium to the average closing price over the past five days. The gross proceeds from this subscription are expected to be over HK$100 million, with net proceeds earmarked for research and development, marketing, loan repayment, and daily operations. The subscription is subject to approval from the Stock Exchange, and trading of the company’s shares was temporarily halted pending this announcement.

CANbridge Pharmaceuticals Announces Trading Halt Pending Inside Information
Aug 12, 2025

CANbridge Pharmaceuticals Inc. has announced a trading halt on its shares on the Hong Kong Stock Exchange, effective from August 12, 2025. This halt is pending the release of an announcement containing inside information, which may have significant implications for the company’s operations and its stakeholders.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 29, 2025