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GlaxoSmithKline (GSK)
NYSE:GSK
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GlaxoSmithKline (GSK) AI Stock Analysis

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GSK

GlaxoSmithKline

(NYSE:GSK)

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Outperform 78 (OpenAI - 4o)
Rating:78Outperform
Price Target:
$44.00
▼(-0.34% Downside)
GSK's overall stock score is driven by strong earnings performance and positive technical indicators. The company's robust financial health and strategic focus on high-growth segments provide a solid foundation for future growth. Valuation metrics are favorable, and the positive sentiment from the earnings call further supports the stock's outlook.
Positive Factors
R&D Achievements
GSK's success in obtaining FDA approvals underscores its strong R&D capabilities, enhancing its competitive position and potential for future growth.
Positive Cash Flow
Robust cash flow supports GSK's ability to invest in growth opportunities and return value to shareholders, indicating financial stability.
New Product Approval
The approval of gepotidacin expands GSK's product portfolio, potentially driving revenue growth and strengthening its market position in antibiotics.
Negative Factors
Supply Chain and Cost Challenges
Rising supply chain costs can pressure margins, potentially impacting profitability if not managed effectively over the long term.
Regulatory Delays
Regulatory delays for Blenrep may hinder GSK's ability to capitalize on new market opportunities, affecting revenue growth in the near term.
China Market Challenges
Difficulties in the Chinese market could limit GSK's growth potential in a key region, impacting overall sales and market expansion efforts.

GlaxoSmithKline (GSK) vs. SPDR S&P 500 ETF (SPY)

GlaxoSmithKline Business Overview & Revenue Model

Company DescriptionGSK plc, together with its subsidiaries, engages in the research, development, and manufacture of vaccines, and specialty and general medicines to prevent and treat disease in the United Kingdom, the United States, and internationally. It operates through two segments, Commercial Operations and Total R&D. The company offers shingles, meningitis, respiratory syncytial virus, flu, polio, influenza, and pandemic vaccines. It also provides medicines for HIV, oncology, respiratory/immunology, and other specialty medicine products, as well as inhaled medicines for asthma and chronic obstructive pulmonary disease, and antibiotics for infections. It has a collaboration agreement with CureVac to develop mRNA-based influenza vaccines, and with Wave Life Sciences and Elsie Biotechnologies, Inc for oligonucleotide platform development; two strategic collaborations with Relation to advance therapeutics for fibrotic diseases and osteoarthritis; and multi-target strategic alliance with GSK to develop breakthrough treatments for people afflicted with Parkinson's disease; as well as collaboration with Flagship Pioneering to discover novel medicines and vaccines. The company was formerly known as GlaxoSmithKline plc and changed its name to GSK plc in May 2022. GSK plc was founded in 1715 and is headquartered in Brentford, the United Kingdom.dom.
How the Company Makes MoneyGSK generates revenue primarily through the sale of its pharmaceutical products, vaccines, and consumer healthcare items. The pharmaceuticals segment is the largest revenue contributor, driven by sales of key drugs and ongoing investments in research and development to introduce new therapies. The vaccines division also plays a crucial role, with revenue stemming from both established vaccines and new product launches targeting global health needs. The consumer healthcare segment provides steady income through a portfolio of well-known brands. Additionally, GSK engages in strategic partnerships and collaborations with other companies and research institutions, which can lead to shared development costs and expanded market reach. The company also benefits from licensing agreements and royalty income, further diversifying its revenue streams.

GlaxoSmithKline Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Breaks down revenue by different business segments, highlighting which areas drive the most sales and profitability, and indicating where the company might focus its strategic efforts.
Chart InsightsGSK's Specialty Medicines segment has emerged as a key growth driver, with recent earnings highlighting a 15% sales increase, aligning with its projected dominance by 2031. While the Vaccines segment also shows positive momentum with a 9% rise, challenges persist in China and supply chain costs. The company's strategic focus on R&D and successful FDA approvals bolster its long-term growth outlook, despite delayed product launches. GSK's robust cash generation supports continued investments and shareholder returns, positioning it well to reach the upper end of its 2025 financial guidance.
Data provided by:Main Street Data

GlaxoSmithKline Earnings Call Summary

Earnings Call Date:Jul 30, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Oct 29, 2025
Earnings Call Sentiment Neutral
GSK reported strong financial performance with significant growth in Specialty Medicines and vaccines. However, challenges in supply chain costs, regulatory delays for Blenrep, and difficulties in the Chinese market were notable concerns.
Q2-2025 Updates
Positive Updates
Strong Financial Performance
Group sales increased by 6% for the quarter, core operating profit rose by 12%, and core earnings per share grew by 15% to 46.5p. Specialty Medicines sales were up 15%, and vaccine sales increased by 9%.
R&D Achievements
Three FDA approvals were achieved so far this year. The company is making progress in R&D with several pivotal trial readouts and new high-potential assets entering late-stage development.
Positive Cash Flow and Shareholder Returns
Cash generation remains strong with GBP 3.7 billion generated in the first half. More than GBP 800 million of the share buyback program has been completed, and the dividend for the quarter was 16p.
Guidance Update
GSK now expects to be towards the top end of the financial guidance given for 2025, reflecting strong performance momentum.
Negative Updates
Supply Chain and Cost Challenges
Cost of sales grew 7% ahead of sales due to pricing impacts and supply chain optimization charges, affecting the gross margin.
Regulatory Delays for Blenrep
The FDA has extended the review period for Blenrep, with a new target action date of the 23rd of October, delaying potential U.S. market entry.
China Market Challenges
There are ongoing challenges in the Chinese market affecting vaccine sales, particularly for Shingrix.
Company Guidance
In the GSK Q2 2025 Results Call, the company reported a strong performance with group sales up by 6% and core operating profit increasing by 12%. Core earnings per share grew 15% to 46.5p. Specialty Medicines, the largest segment, showed robust growth of 15%, while vaccines also contributed with a 9% sales increase. The company has achieved three FDA approvals this year, maintaining a positive cash generation of GBP 3.7 billion in the first half. A dividend of 16p was declared, and over GBP 800 million worth of shares have been bought back since February. GSK is progressing towards the top end of its 2025 financial guidance, driven by investments in 14 major scale opportunities with expected peak year sales above GBP 2 billion. The company aims for Specialty Medicines to account for over 50% of sales by 2031.

GlaxoSmithKline Financial Statement Overview

Summary
GSK demonstrates strong financial health with robust profitability, efficient asset utilization, and stable cash flows. Modest revenue growth is offset by improved profitability and solid cash flow conversion. The balance sheet shows moderate leverage, which is manageable given current equity returns and cash generation.
Income Statement
75
Positive
The income statement reflects healthy profitability and growth signs. The gross profit margin is robust, consistently above 70%, indicating strong pricing power and cost control. The TTM net profit margin is 10.0%, showing an improvement from the previous year. Revenue growth is modest at 0.49% from the prior year, suggesting stability. EBIT and EBITDA margins improved to 16.1% and 26.1% respectively, highlighting better operational efficiency.
Balance Sheet
65
Positive
The balance sheet shows moderate leverage with a debt-to-equity ratio of 1.30, indicating a significant reliance on debt, though not excessively high for the industry. Return on equity stands at 22.3% TTM, reflecting efficient use of equity to generate profits. The equity ratio is 23.3%, suggesting a balanced asset structure, though there is room for strengthening the equity position.
Cash Flow
70
Positive
The cash flow statement reveals a positive trajectory in cash generation. Free cash flow increased by 1.99% year-over-year, supporting future investments or debt reduction. The operating cash flow to net income ratio is a healthy 2.07 TTM, indicating solid cash conversion. However, the free cash flow to net income ratio is 1.16, reflecting potential for further improvement in cash flow efficiency.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue31.63B31.38B30.33B29.32B34.11B34.10B
Gross Profit22.57B22.33B21.76B19.77B22.51B22.39B
EBITDA8.61B6.67B9.14B8.63B7.76B10.16B
Net Income3.42B2.58B4.93B4.92B4.38B5.75B
Balance Sheet
Total Assets59.26B59.46B59.01B60.15B79.10B80.43B
Cash, Cash Equivalents and Short-Term Investments3.62B3.71B4.99B7.88B4.33B6.37B
Total Debt0.0016.99B18.02B20.99B24.17B27.15B
Total Liabilities44.90B46.38B46.21B50.05B57.76B59.62B
Stockholders Equity14.79B13.67B13.35B10.60B15.05B14.59B
Cash Flow
Free Cash Flow4.67B3.57B4.42B5.14B5.02B6.20B
Operating Cash Flow7.72B6.55B6.77B7.40B7.95B8.44B
Investing Cash Flow-3.62B-1.23B-1.59B-8.77B-1.78B2.16B
Financing Cash Flow-3.60B-4.73B-5.64B823.00M-7.59B-10.13B

GlaxoSmithKline Technical Analysis

Technical Analysis Sentiment
Positive
Last Price44.15
Price Trends
50DMA
40.48
Positive
100DMA
39.51
Positive
200DMA
37.61
Positive
Market Momentum
MACD
1.04
Negative
RSI
65.28
Neutral
STOCH
43.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GSK, the sentiment is Positive. The current price of 44.15 is above the 20-day moving average (MA) of 42.21, above the 50-day MA of 40.48, and above the 200-day MA of 37.61, indicating a bullish trend. The MACD of 1.04 indicates Negative momentum. The RSI at 65.28 is Neutral, neither overbought nor oversold. The STOCH value of 43.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GSK.

GlaxoSmithKline Risk Analysis

GlaxoSmithKline disclosed 1 risk factors in its most recent earnings report. GlaxoSmithKline reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

GlaxoSmithKline Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$87.23B20.0423.04%3.73%3.46%-13.29%
77
Outperform
$140.89B13.1812.16%6.91%14.72%
77
Outperform
$264.43B31.4919.76%1.84%15.08%29.15%
76
Outperform
$117.58B11.968.39%4.49%-9.32%120.62%
70
Outperform
$156.19B23.7499.14%3.21%13.10%110.67%
68
Neutral
$89.48B17.7429.31%5.66%2.57%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GSK
GlaxoSmithKline
44.15
6.86
18.40%
AMGN
Amgen
293.85
-20.72
-6.59%
AZN
AstraZeneca
85.12
8.87
11.63%
BMY
Bristol-Myers Squibb
43.80
-6.46
-12.85%
PFE
Pfizer
24.52
-2.99
-10.87%
SNY
Sanofi
49.22
-3.66
-6.92%

GlaxoSmithKline Corporate Events

GSK Executes Share Buyback as Part of Capital Management Strategy
Aug 29, 2025

On August 28, 2025, GSK plc announced the purchase of 236,167 of its own ordinary shares at prices ranging from 1,460.50p to 1,479.00p per share, as part of its ongoing buyback program initiated on June 4, 2025. This transaction, executed through Merrill Lynch International, increases the total number of shares held in treasury to 244,155,883, representing 6.00% of the voting rights, and reflects GSK’s strategy to manage its capital structure effectively.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2025