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Glaukos Corp. (GKOS)
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Glaukos (GKOS) AI Stock Analysis

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GKOS

Glaukos

(NYSE:GKOS)

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Neutral 52 (OpenAI - 4o)
Rating:52Neutral
Price Target:
$89.00
▲(6.13% Upside)
Glaukos's overall score is driven by strong sales growth and positive future guidance, as highlighted in the earnings call. However, significant challenges in profitability, cash flow management, and valuation metrics weigh heavily on the score. Technical indicators suggest bearish momentum, further impacting the stock's attractiveness.
Positive Factors
Revenue Growth
Exceeding revenue expectations indicates strong market demand and effective execution of strategic plans, supporting long-term growth.
Product Approval
FDA approval of Epioxa enhances product portfolio, offering a competitive edge and potential for increased market share in ophthalmic treatments.
Strategic Expansion
The new facility supports long-term growth and innovation, strengthening U.S. operations and enhancing capacity for future product development.
Negative Factors
Profitability Challenges
Ongoing profitability issues may hinder financial stability and limit reinvestment opportunities, affecting long-term business sustainability.
Cash Flow Issues
Negative cash flows indicate potential liquidity constraints, impacting the company's ability to fund operations and strategic initiatives.
Market Access Challenges
Difficulties in market access and reimbursement could limit the adoption of new products, affecting revenue growth and market penetration.

Glaukos (GKOS) vs. SPDR S&P 500 ETF (SPY)

Glaukos Business Overview & Revenue Model

Company DescriptionGlaukos Corporation is a medical technology company focused on the development and commercialization of innovative surgical devices and therapies for the treatment of glaucoma and other diseases of the eye. Founded in 1998 and headquartered in San Clemente, California, Glaukos operates primarily in the ophthalmic sector, offering products such as the iStent and iStent inject, which are designed to reduce intraocular pressure in patients with glaucoma. The company is dedicated to enhancing patient outcomes through its minimally invasive surgical approaches, which aim to provide safer and more effective treatment options for eye care professionals and their patients.
How the Company Makes MoneyGlaukos generates revenue primarily through the sale of its surgical devices and related products for the treatment of glaucoma. The company's key revenue streams include the direct sales of its iStent and iStent inject devices, as well as revenue from related consumables and accessories. Glaukos also benefits from strategic partnerships with ophthalmology clinics and hospitals, which help to expand its market reach and distribution capabilities. Additionally, the company may explore partnerships with other healthcare organizations for product development, clinical studies, and co-marketing agreements, contributing to its overall revenue growth. As the prevalence of glaucoma and the demand for innovative treatment options increase, Glaukos is positioned to capitalize on these trends within the ophthalmic market.

Glaukos Earnings Call Summary

Earnings Call Date:Oct 29, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
Glaukos showcased strong financial performance with record sales and significant product approvals, particularly the FDA approval of Epioxa. However, the company faces challenges with transitioning its Corneal Health franchise and establishing market access for new products.
Q3-2025 Updates
Positive Updates
Record Third Quarter Sales
Glaukos reported record third quarter consolidated net sales of $133.5 million, up 38% on a reported basis or 37% on a constant currency basis versus the year-ago quarter.
iDose TR Adoption
The U.S. Glaucoma franchise delivered record third quarter net sales of $80.8 million, with iDose TR generating sales of approximately $40 million in the third quarter.
Epioxa FDA Approval
FDA approved Epioxa for corneal cross-linking for keratoconus, marking a significant milestone as the first and only FDA-approved topical drug therapy that does not require the removal of the corneal epithelium.
Raised Full-Year 2025 Guidance
Full-year 2025 net sales guidance raised to $490 million to $495 million from $480 million to $486 million.
Strong International Growth
International Glaucoma franchise net sales of $29.4 million, marking a year-over-year growth of 20% on a reported basis and 17% on a constant currency basis.
Negative Updates
Corneal Health Franchise Transition
The transition from Photrexa to Epioxa may lead to a material year-over-year decline in the fourth quarter for the Corneal Health franchise.
Reimbursement and Market Access Challenges
Challenges with establishing professional fees in some MAC regions and the need for extensive payer education for Epioxa.
Epioxa Pricing Concerns
The wholesale acquisition cost for Epioxa is set at $78,500, which may lead to challenges in payer coverage and patient access.
Company Guidance
During the third-quarter 2025 earnings call, Glaukos Corporation reported record consolidated net sales of $133.5 million, marking a 38% increase on a reported basis and 37% on a constant currency basis compared to the same period last year. This performance prompted the company to raise its full-year 2025 net sales guidance from the previously projected range of $480 million to $486 million, up to $490 million to $495 million. Contributing significantly to these results was the strong adoption of iDose TR, which alone generated approximately $40 million in third-quarter sales. The U.S. Glaucoma franchise achieved record net sales of $80.8 million, reflecting a 57% year-over-year growth, while the International Glaucoma franchise delivered $29.4 million in net sales, up 20% on a reported basis. The Corneal Health franchise also grew by 13%, with net sales reaching $23.3 million. Additionally, Glaukos introduced a preliminary 2026 revenue guidance range of $600 million to $620 million, driven by ongoing momentum and the upcoming launch of Epioxa, a newly FDA-approved treatment for keratoconus.

Glaukos Financial Statement Overview

Summary
Glaukos shows potential with revenue growth and a strong gross profit margin. However, profitability issues and negative cash flow highlight significant operational inefficiencies and cash constraints.
Income Statement
45
Neutral
Glaukos shows a positive revenue growth trend with a TTM growth rate of 8.52%, indicating potential market expansion. However, the company struggles with profitability, as evidenced by negative net profit and EBIT margins. The gross profit margin remains strong at 76.87%, but the persistent negative net income highlights challenges in cost management and operational efficiency.
Balance Sheet
55
Neutral
The balance sheet reflects a stable financial structure with a low debt-to-equity ratio of 0.14, suggesting manageable leverage. However, the negative return on equity indicates inefficiencies in generating profits from shareholders' investments. The equity ratio of 76.98% shows a strong equity base, providing a cushion against financial volatility.
Cash Flow
40
Negative
Cash flow analysis reveals a challenging scenario with negative operating cash flow, indicating operational cash constraints. Despite a positive free cash flow growth rate, the company struggles to convert net income into cash, as shown by the negative operating cash flow to net income ratio. The free cash flow to net income ratio above 1 suggests reliance on non-operational cash inflows.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue469.82M383.48M314.71M282.86M294.01M224.96M
Gross Profit361.14M289.45M239.14M213.88M227.38M133.24M
EBITDA-38.86M-95.64M-82.12M-48.76M-1.47M-83.59M
Net Income-87.61M-146.37M-134.66M-99.19M-49.59M-120.35M
Balance Sheet
Total Assets999.38M974.76M940.41M1.00B1.05B1.01B
Cash, Cash Equivalents and Short-Term Investments273.71M318.92M295.43M352.69M414.05M404.37M
Total Debt104.31M105.87M383.74M382.48M382.38M270.81M
Total Liabilities229.84M207.82M478.65M472.38M462.55M338.05M
Stockholders Equity769.54M766.93M461.77M530.00M587.15M667.45M
Cash Flow
Free Cash Flow-27.61M-67.62M-78.01M-63.35M-23.08M-29.92M
Operating Cash Flow-21.13M-61.32M-57.76M-33.08M24.71M-22.99M
Investing Cash Flow-49.94M47.83M14.10M44.78M-58.23M-205.06M
Financing Cash Flow69.57M91.54M15.04M6.25M39.26M262.54M

Glaukos Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price83.86
Price Trends
50DMA
84.41
Negative
100DMA
90.03
Negative
200DMA
99.24
Negative
Market Momentum
MACD
0.01
Negative
RSI
51.41
Neutral
STOCH
34.32
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GKOS, the sentiment is Neutral. The current price of 83.86 is above the 20-day moving average (MA) of 81.91, below the 50-day MA of 84.41, and below the 200-day MA of 99.24, indicating a neutral trend. The MACD of 0.01 indicates Negative momentum. The RSI at 51.41 is Neutral, neither overbought nor oversold. The STOCH value of 34.32 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GKOS.

Glaukos Risk Analysis

Glaukos disclosed 25 risk factors in its most recent earnings report. Glaukos reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Glaukos Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$1.72B26.2018.31%29.47%23.24%
63
Neutral
$2.39B27.905.18%7.81%-26.32%
57
Neutral
$900.70M-111.91%25.84%-47.67%
56
Neutral
$5.82B-53.15%25.45%66.62%
52
Neutral
$4.70B-12.19%30.38%47.64%
52
Neutral
$2.77B-17.63%8.97%-1024.86%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GKOS
Glaukos
83.86
-59.18
-41.37%
ITGR
Integer Holdings
68.26
-71.23
-51.06%
UFPT
Ufp Technologies
226.11
-117.38
-34.17%
TNDM
Tandem Diabetes Care
16.26
-15.11
-48.17%
LIVN
LivaNova
50.45
-1.36
-2.62%
IRTC
Irhythm Technologies
174.60
85.67
96.33%

Glaukos Corporate Events

Glaukos Corp. Reports Record Sales and FDA Approval
Oct 31, 2025

Glaukos Corp. recently held its earnings call, revealing a strong financial performance marked by record sales and significant product approvals. The sentiment was generally positive, with the FDA approval of Epioxa being a notable highlight. However, challenges remain, particularly in transitioning the Corneal Health franchise and establishing market access for new products.

Glaukos Corp. Reports Record Q3 Sales Growth
Oct 30, 2025

Glaukos Corporation is an ophthalmic pharmaceutical and medical technology company that specializes in developing innovative therapies for glaucoma, corneal disorders, and retinal diseases. The company is known for pioneering Micro-Invasive Glaucoma Surgery (MIGS) and continues to advance its portfolio with novel, dropless platform technologies.

Business Operations and StrategyFinancial Disclosures
Glaukos Reports Record Q3 2025 Sales Growth
Positive
Oct 29, 2025

In its third quarter of 2025, Glaukos reported record net sales of $133.5 million, marking a 38% increase year-over-year. The company raised its 2025 net sales guidance and introduced preliminary 2026 guidance, reflecting strong business momentum and strategic execution. Despite a net loss, the company showed improved financial performance compared to the previous year, with increased sales, gross margins, and reduced operating losses.

The most recent analyst rating on (GKOS) stock is a Buy with a $120.00 price target. To see the full list of analyst forecasts on Glaukos stock, see the GKOS Stock Forecast page.

Glaukos Corp. Advances NEXAGON® Study for Eye Condition Treatment
Oct 27, 2025

Glaukos Corp. is conducting a study titled ‘A Randomized, Multicenter, Double-Masked, Vehicle-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With Persistent Corneal Epithelial Defects (NEXPEDE-1)’. The study aims to assess the safety and effectiveness of NEXAGON® in treating persistent corneal epithelial defects (PCED), a condition that can lead to significant vision problems.

Glaukos Corp. Advances in Glaucoma Treatment with New Clinical Trial
Oct 27, 2025

Glaukos Corp. is currently recruiting participants for a Phase 2/Phase 3 clinical trial titled Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant. The study aims to assess the safety and effectiveness of the second-generation Travoprost intracameral implant in treating glaucoma, a significant eye condition that can lead to vision loss.

Glaukos Corp.’s iDose TR Study: A Potential Game-Changer in Ophthalmic Treatment
Oct 27, 2025

Glaukos Corp. is conducting a clinical study titled ‘Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone.’ This study aims to assess the safety and effectiveness of the iDose TR, a travoprost intracameral implant, when used alongside cataract surgery. The trial’s significance lies in its potential to offer a new treatment option for patients with open-angle glaucoma and ocular hypertension undergoing cataract surgery.

Business Operations and StrategyProduct-Related Announcements
Glaukos Highlights Innovation in Recent Investor Presentation
Positive
Aug 12, 2025

Glaukos Corporation’s recent investor presentation highlights its strategic focus on innovation and commercial excellence, aiming to improve standards of care in ophthalmology. The company is advancing its iDose TR therapy, a groundbreaking sustained-release drug delivery system for glaucoma, which is expected to enhance patient compliance and outcomes by reducing reliance on traditional topical medications.

The most recent analyst rating on (GKOS) stock is a Buy with a $139.00 price target. To see the full list of analyst forecasts on Glaukos stock, see the GKOS Stock Forecast page.

Glaukos Corp. Reports Record Growth Amid Challenges
Aug 1, 2025

Glaukos Corp. recently held its earnings call, revealing a generally positive sentiment driven by strong financial performance and strategic advancements. The company reported record net sales and significant growth in key segments, such as the U.S. glaucoma franchise and international markets. Despite these achievements, challenges persist, including the impact of MAC LCDs on the MIGS market and potential disruptions from proposed CMS reimbursement changes. Nevertheless, the company’s positive achievements and strategic advancements appear to outweigh these challenges.

Glaukos Corporation Reports Strong Q2 2025 Growth
Jul 31, 2025

Glaukos Corporation is an ophthalmic pharmaceutical and medical technology company that specializes in developing innovative therapies for glaucoma, corneal disorders, and retinal diseases. The company is known for pioneering Micro-Invasive Glaucoma Surgery (MIGS) and continues to expand its portfolio with novel, dropless platform technologies.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 31, 2025