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Circassia Pharmaceuticals PLC (GB:NIOX)
LSE:NIOX
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Circassia Pharmaceuticals (NIOX) AI Stock Analysis

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GB:NIOX

Circassia Pharmaceuticals

(LSE:NIOX)

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Outperform 73 (OpenAI - Gpt-5.6Sol)
Rating:73Outperform
Price Target:
77.00 p
▲(12.90% Upside)
Action:Upgraded
Date:10/01/26
The score is primarily supported by strong financial quality (growth, profitability, low leverage, and solid cash generation) and a positive technical trend with constructive momentum. These strengths are tempered by valuation risk from a high P/E multiple and some recent pressure in gross margin and free cash flow.
Positive Factors
Revenue growth and profitability
Sustained multi-year revenue expansion, combined with a healthy operating margin, indicates stronger demand and improving operating scale. The shift from earlier losses to consistent profitability supports reinvestment, resilience, and the potential for durable earnings generation over coming quarters.
Negative Factors
Gross-margin pressure
The gross-margin decline indicates that recent revenue growth has not translated fully into stable underlying economics. If mix, pricing, or cost pressure persists, it could constrain operating leverage and make future profit expansion more dependent on continued volume growth or expense control.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue growth and profitability
Sustained multi-year revenue expansion, combined with a healthy operating margin, indicates stronger demand and improving operating scale. The shift from earlier losses to consistent profitability supports reinvestment, resilience, and the potential for durable earnings generation over coming quarters.
Read all positive factors

Circassia Pharmaceuticals (NIOX) vs. iShares MSCI United Kingdom ETF (EWC)

Circassia Pharmaceuticals Business Overview & Revenue Model

Company Description
NIOX Group Plc is a worldwide company dedicated to innovating, developing, and distributing medical devices that measure fractional exhaled nitric oxide (FeNO). A key product is the NIOX VERO system, an easily portable and non-invasive diagnostic ...
How the Company Makes Money
Circassia makes money primarily by commercializing its NIOX® FeNO testing ecosystem. Revenue is generated through (1) sales or placements of NIOX instruments (the testing devices used by clinics and hospitals), and (2) recurring sales of associate...

Circassia Pharmaceuticals Financial Statement Overview

Summary
Strong multi-year revenue growth (27.9m in 2021 to 48.7m in 2025), solid operating profitability (~22% operating margin in 2025), very low leverage, and consistently positive cash generation. Key risks are margin normalization (gross margin step-down in 2025) and a 2025 decline in free cash flow (~17% YoY) despite higher revenue.
Income Statement
74
Positive
Balance Sheet
88
Very Positive
Cash Flow
77
Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue47.50M48.70M41.80M36.80M31.30M27.90M
Gross Profit28.70M29.60M30.20M26.50M22.20M19.00M
EBITDA14.70M14.80M12.20M8.60M15.20M3.10M
Net Income7.00M7.00M3.70M10.70M16.10M3.60M
Balance Sheet
Total Assets73.10M76.20M68.40M91.50M98.50M86.40M
Cash, Cash Equivalents and Short-Term Investments16.80M19.90M10.90M19.90M19.40M12.60M
Total Debt700.00K1.00M1.50M1.10M1.00M1.30M
Total Liabilities7.00M8.60M8.90M7.70M16.60M19.60M
Stockholders Equity66.10M73.70M59.50M83.80M81.90M66.80M
Cash Flow
Free Cash Flow12.50M15.60M16.20M11.30M6.60M1.20M
Operating Cash Flow12.70M15.80M17.20M11.60M6.70M1.40M
Investing Cash Flow-700.00K-1.20M-1.00M-300.00K-100.00K-200.00K
Financing Cash Flow-7.10M-5.50M-25.10M-10.50M-500.00K4.10M

Circassia Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price68.20
Price Trends
50DMA
67.25
Negative
100DMA
63.39
Positive
200DMA
62.34
Positive
Market Momentum
MACD
0.36
Positive
RSI
44.02
Neutral
STOCH
56.52
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:NIOX, the sentiment is Neutral. The current price of 68.2 is above the 20-day moving average (MA) of 67.57, above the 50-day MA of 67.25, and above the 200-day MA of 62.34, indicating a neutral trend. The MACD of 0.36 indicates Positive momentum. The RSI at 44.02 is Neutral, neither overbought nor oversold. The STOCH value of 56.52 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GB:NIOX.

Circassia Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
£101.88M13.7365.83%7.69%-8.21%-5.27%
73
Outperform
£290.40M39.5210.01%2.35%3.26%32.54%
64
Neutral
£105.71M41.813.58%4.36%2.26%-57.04%
62
Neutral
£173.48M-629.69-0.68%―20.14%82.22%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
£22.75M-16.36-34.31%―30.42%43.16%
42
Neutral
£284.96M-4.54409.00%―2.94%-32.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:NIOX
Circassia Pharmaceuticals
67.80
-0.44
-0.64%
GB:AGY
Allergy Therapeutics
4.50
-3.70
-45.12%
GB:BVXP
Bioventix
2,000.00
-156.81
-7.27%
GB:EKF
EKF Diagnostics Holdings
24.30
-3.65
-13.06%
GB:DXRX
Diaceutics
199.00
38.50
23.99%
GB:ABDX
Abingdon Health PLC
9.00
2.75
44.00%

Circassia Pharmaceuticals Corporate Events

Stock BuybackShareholder Meetings
NIOX Group Launches £12.5m Tender Offer Buyback at Premium Price
Positive
Sep 29, 2026
NIOX Group plc has announced a proposed return of up to £12.5 million to shareholders through a tender offer to buy back as many as 15,625,000 ordinary shares at 80 pence per share, representing a premium to recent market prices and around 3....
Business Operations and StrategyStock BuybackDividendsFinancial DisclosuresRegulatory Filings and Compliance
NIOX Group Delivers Resilient H1, Launches Major Cash Return Amid FeNO Expansion
Positive
Sep 29, 2026
NIOX Group reported a resilient first half to 2026, with revenue edging down to £24.0 million from £25.2 million amid lower research sales, while clinical revenue grew 3% to £20.6 million and gross margin improved to 71%. Adjusted E...
Business Operations and StrategyStock BuybackFinancial DisclosuresProduct-Related AnnouncementsRegulatory Filings and Compliance
NIOX Group Targets Stronger H2 as NIOX PRO Rollout and Capital Return Plans Advance
Positive
Jul 28, 2026
NIOX Group reported first-half 2026 revenue of about £24m, slightly below the prior year, as strong clinical sales and a higher-margin mix offset lower research revenue driven by a strategic shift in inventory towards the clinical business. A...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 01, 2026