Intellia Therapeutics (0JBU) Share Price & Analysis
0JBU Stock Chart & Stats
- Day’s Range
- $11.90 - $12.53
- 52-Week Range
- $7.91 - $19.20
- Previous Close
- $11.91
- Volume
- N/A
- Average Volume (3M)
- 21.90K
- Market Cap
- $1.66B
- Enterprise Value
- $1.89B
- Total Cash (Recent Filing)
- $437.76M
- Total Debt (Recent Filing)
- $73.41M
- Price to Earnings (P/E)
- ―
- Beta
- 0.67
- Next Earnings
- Nov 05, 2026 (Est.)
- EPS Estimate
- -0.8
- Last Dividend Ex-Date
- Mar 15, 2022
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Lonvo-z Clinical And Regulatory Progress
Lonvo-z has produced strong Phase III efficacy while advancing into FDA Priority Review, materially improving the pathway toward a potential first commercial product. Approval could establish a differentiated one-time HAE treatment and validate Intellia’s in vivo CRISPR platform.
In Vivo Gene-editing Potential
Nex-z demonstrates rapid, deep and durable biological activity from a one-time treatment, supporting the broader potential of Intellia’s gene-editing approach. If later-stage safety and efficacy remain acceptable, this platform could address serious diseases beyond the lead HAE program.
Financial Flexibility And Runway
A substantial cash position and funding runway into at least 2028 give Intellia time to complete key clinical work, pursue regulatory review and prepare for a potential launch. Low balance-sheet leverage also provides flexibility, although future execution remains essential.
Bears Say
Persistent Cash Burn
Intellia remains dependent on external financing because operating activities do not yet generate cash and recent TTM burn has worsened. Continued spending on clinical development and commercialization can consume reserves quickly if approval, partnerships or product revenue are delayed.
Nex-z Liver Safety Risk
The nex-z liver enzyme signal creates a material development and regulatory risk for a major pipeline program. Monitoring, mitigation and regulatory engagement may reduce the issue, but adverse events could complicate dosing, limit eligible patients or delay the program.
Unprofitable Operating Model
Revenue remains modest relative to Intellia’s cost base, leaving the company firmly in an investment phase with deeply negative profitability. This weak earnings profile limits internally funded growth and makes progress toward successful approvals and commercialization critical to future financial sustainability.
Intellia Therapeutics News
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Intellia Therapeutics Stock Smart Score
Company Description
Intellia Therapeutics
Intellia Therapeutics, Inc. is a biotechnology firm dedicated to advancing therapeutic treatments through its expertise in genome editing. The company's pipeline includes several in vivo (administered within the body) programs. NTLA-2001 is currently undergoing a Phase 1 clinical trial for transthyretin amyloidosis, while NTLA-2002 targets hereditary angioedema. Additionally, Intellia is developing various other liver-focused therapies for conditions such as hemophilia A and B, hyperoxaluria Type 1, and alpha-1 antitrypsin deficiency. Its ex vivo (processed outside the body) pipeline features NTLA-5001, a candidate for acute myeloid leukemia. The company is also progressing proprietary programs focused on creating engineered cell therapies to address diverse oncological and autoimmune disorders. At the core of Intellia's technology is the Clustered, Regularly Interspaced Short Palindromic Repeats/CRISPR associated 9 (CRISPR/Cas9) system. Intellia Therapeutics, Inc. has established multiple licensing and collaboration agreements. These include a partnership with Novartis Institutes for BioMedical Research, Inc. to engineer hematopoietic stem cells for treating sickle cell disease, and a co-development agreement with Regeneron Pharmaceuticals, Inc. for potential products against hemophilia A and B. The company also collaborates with Ospedale San Raffaele and holds a strategic alliance with SparingVision SAS to develop novel genomic medicines for ocular diseases, leveraging CRISPR/Cas9 technology. The company, initially known as AZRN, Inc., was founded in 2014 and operates from its headquarters in Cambridge, Massachusetts.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- John Leonard
- Employees
- 377
- Website
- www.intelliatx.com
- Address
- 40 Erie Street, Cambridge, MA, 02139, US
Intellia Therapeutics (0JBU) Earnings & Revenues
0JBU Earnings Call
Earnings Call SentimentPositive
The call conveyed strong, concrete clinical progress — most notably the unequivocal Phase III success for lonvo‑z (87% attack reduction, 62% attack‑free and therapy‑free, favorable safety) and compelling nex‑z biological data (≈90% TTR knockdown, rapid and durable) — alongside active regulatory and commercial preparations. Financially, the company strengthened its cash position with a ~$195M financing and maintains a runway into at least 2028, although collaboration revenue declined and G&A rose as commercial build‑out continues. The primary concern is a nex‑z liver enzyme safety signal and the identification of an HLA C*05:01 subgroup (~12% of samples) associated with higher Grade 3+ transaminase events; the company has implemented mitigation, added HLA typing to protocols, and is engaging regulators. Overall, the positive clinical milestones and clear mitigation plan for the safety finding outweigh the operational and financial headwinds discussed.
View all GB:0JBU earnings summaries0JBU Net sales Breakdown
- 100.00% Collaboration revenue
0JBU Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 5 | 5 | 12 |
| Technical Analysis | 4 | 5 | 1 |
| Moving Averages | 1 | 0 | 11 |













