ACADIA Pharmaceuticals stock analysis
ACADIA Pharmaceuticals (0A4W) Share Price & Analysis
0A4W Stock Chart & Stats
- Day’s Range
- $26.87 - $26.87
- 52-Week Range
- $18.62 - $26.87
- Previous Close
- $26.87
- Volume
- N/A
- Average Volume (3M)
- 0
- Market Cap
- $3.16B
- Enterprise Value
- $2.63B
- Total Cash (Recent Filing)
- $976.45M
- Total Debt (Recent Filing)
- $71.85M
- Price to Earnings (P/E)
- 8.6
- Beta
- 0.11
- Next Earnings
- Mar 01, 2027 (Est.)
- EPS Estimate
- 0.27
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Commercial Expansion
Raised 2026 guidance and stated 2028 sales ambitions for both medicines indicate management sees commercial expansion as durable, not dependent on a single quarter. DAYBUE and NUPLAZID growth can broaden the revenue base, support operating leverage, and fund continued CNS investment.
Balance Sheet Strength
Low leverage and expanding equity provide financial resilience while ACADIA invests in commercialization and clinical development. The shift to positive returns on equity also shows that improved capitalization is being supported by a meaningful profitability turnaround rather than balance-sheet growth alone.
Extended Product Protection
Protection through 2041 could preserve DAYBUE’s commercial economics for many years and give ACADIA a durable period to expand diagnosis, community-practice use, and international access. Longer exclusivity also supports confidence in funding pipeline development from an established product franchise.
Bears Say
Free Cash Flow Volatility
The sharp recent decline in free cash flow weakens confidence in the quality and repeatability of reported earnings. If cash conversion remains below net income, ACADIA may have less internally generated flexibility for clinical programs, commercial investment, and business development despite positive profitability.
Cooling Revenue Growth
Slower revenue growth and less consistent operating profitability suggest that the initial acceleration is moderating. This could make future earnings more dependent on execution, expense control, and successful indication expansion, reducing visibility into how sustainably current profit levels can compound.
Clinical Development Risk
The missed primary endpoint raises uncertainty around remlifanserin’s probability of success and the timing of any future contribution from the program. Although the 60-milligram dose showed supportive secondary results, additional development and regulatory work remain necessary before commercialization.
ACADIA Pharmaceuticals News
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ACADIA Pharmaceuticals Stock Smart Score
Company Description
ACADIA Pharmaceuticals
Acadia Pharmaceuticals Inc. operates as a biopharmaceutical company, primarily dedicated to discovering, developing, and commercializing small molecule therapeutics. Their core focus lies in addressing critical unmet medical needs within the realm of central nervous system (CNS) disorders. The company's marketed product, NUPLAZID (pimavanserin), is prescribed for the management of hallucinations and delusions associated with Parkinson's disease psychosis. Beyond its commercialized offering, ACADIA maintains a robust development pipeline, featuring several promising candidates: Pimavanserin: This compound is currently undergoing Phase 3 clinical trials for additional indications, specifically for Alzheimer's disease psychosis and the negative symptoms of schizophrenia. Trofinetide: A novel synthetic compound, Trofinetide is also in Phase 3 development, aimed at treating Rett syndrome. ACP-044: This orally administered, first-in-class non-opioid analgesic is progressing through Phase 2 studies for both acute and chronic pain. ACP-319: Identified as a positive allosteric modulator of the muscarinic receptor, ACP-319 is in Phase 1 development, exploring its potential for schizophrenia and improving cognition in Alzheimer's patients. Established in 1993, ACADIA Pharmaceuticals Inc. is headquartered in San Diego, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Catherine E. Owen Adams
- Employees
- 797
- Website
- www.acadia.com
- Address
- 12830 El Camino Real, San Diego, CA, 92130, US
ACADIA Pharmaceuticals (0A4W) Earnings & Revenues
0A4W Company Deck
0A4W Earnings Call
Earnings Call SentimentPositive
The call conveyed strongly positive commercial momentum, with record DAYBUE sales, substantial STIX adoption, European approval, extended patent protection, continued NUPLAZID growth, and a strong cash position. The pipeline outlook was constructive, supported by a clear 60-milligram remlifanserin efficacy signal, favorable safety findings, and multiple development programs, although the RADIANT primary endpoint narrowly missed statistical significance and the company is managing a leadership transition and timing-related NUPLAZID guidance constraints. Highlights significantly outweighed the lowlights.
View all GB:0A4W earnings summaries0A4W Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 14 | 0 | 0 |
| Technical Analysis | 2 | 0 | 0 |
| Moving Averages | 12 | 0 | 0 |










