The earnings call reflects a positive sentiment with significant revenue growth in key products and accelerated progress in the pipeline, despite some challenges with sequential sales decline and increased R&D expenses.
Company Guidance
During ACADIA Pharmaceuticals' first quarter 2025 conference call, the company outlined its strong financial performance and strategic initiatives. The call highlighted a 19% increase in total revenue, reaching $244.3 million, with DAYBUE and NUPLAZID sales rising by 11% and 23%, respectively. DAYBUE achieved $84.6 million in sales with 954 unique patients, while NUPLAZID recorded $159.7 million in revenue. The persistency rate for DAYBUE remained above 50% after 12 months, and NUPLAZID benefited from a one-time gross-to-net adjustment. The company reiterated its full-year guidance for both products and raised its R&D expense projection to $330-350 million. ACADIA also accelerated its COMPASS PWS Phase 3 study timeline, expecting results by the end of 2025. Internationally, plans are underway for DAYBUE's European launch, with anticipated EMA approval in early 2026. The company emphasized its commitment to strategic priorities, including expanding its commercial reach and advancing its pipeline.
Strong Revenue Growth
First quarter 2025 revenues reached $244.3 million, up 19% from the previous year.
DAYBUE Sales Increase
DAYBUE sales were $84.6 million in the first quarter, marking an 11% increase from the previous year with 954 unique patients, an all-time record for the brand.
NUPLAZID Revenue Growth
NUPLAZID reported first quarter sales of $159.7 million, up 23% from the prior year, with 6% growth in volume.
Accelerated Pipeline Progress
The timeline for the COMPASS PWS Phase 3 trial has accelerated, with top-line results expected by early fourth quarter 2025.
European Expansion Plans
Preparations for European launch of DAYBUE are underway, with regulatory approval anticipated in Q1 2026.
ACADIA Pharmaceuticals (GB:0A4W) Earnings, Revenues Date & History
The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed
GB:0A4W Earnings-Related Price Changes
Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
May 07, 2025
$18.62
$18.62
0.00%
Feb 26, 2025
$18.62
$18.62
0.00%
Nov 06, 2024
$15.68
$17.26
+10.08%
Aug 06, 2024
$18.90
$15.49
-18.03%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.
FAQ
When does ACADIA Pharmaceuticals Inc. (GB:0A4W) report earnings?
ACADIA Pharmaceuticals Inc. (GB:0A4W) is schdueled to report earning on Jul 30, 2025, TBA Not Confirmed.
What is ACADIA Pharmaceuticals Inc. (GB:0A4W) earnings time?
ACADIA Pharmaceuticals Inc. (GB:0A4W) earnings time is at Jul 30, 2025, TBA Not Confirmed.
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