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Erasca (ERAS) Drug Pipeline

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Drug pipeline
Drug NameConditionStageStatusStudy NameTrial Start DateArticle
Eras-4001, Eras-4001 In CombinationMetastatic Solid TumorsPhase IRecruitingA Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.Jun 06, 2025
Eras-0015, Eras-0015 In CombinationMetastatic Solid TumorsPhase IRecruitingA Study of ERAS-0015 in Patients With Advanced or Metastatic Solid TumorsMay 14, 2025
Temozolomide, Trametinib, Dacarbazine, NaporafenibAdvanced Or Metastatic Nras-Mutant MelanomaPhase IIIActive Not RecruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)Mar 17, 2024
Trametinib, NaporafenibAdvanced Or Metastatic Solid TumorsPhase IActive Not RecruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X MutationsMay 30, 2023―
Eras-801Glioblastoma MultiformePhase IActive Not RecruitingA Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1)Jan 24, 2022―
Encorafenib, Palbociclib, Cetuximab, Eras-007Metastatic Colorectal Cancer, Metastatic Pancreatic Ductal Adenocarcinomaphase1AndPhase2CompletedA Study of ERAS-007 in Patients With Advanced Gastrointestinal MalignanciesSep 01, 2021
Eras-601, Eras-007Advanced Or Metastatic Solid Tumorsphase1AndPhase2CompletedA Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Solid TumorsApr 24, 2021―
Pembrolizumab, Cetuximab, Eras-601Advanced Or Metastatic Solid TumorsPhase ICompletedA Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid TumorsDec 11, 2020―

FAQ

What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases: a. Preclinical testing b. Phase 1 – Safety and dosage c. Phase 2 – Effectiveness and side effects d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Erasca, Inc. (ERAS) have in its pipeline
Erasca ERAS is currently developing the following drugs: Eras-4001, Eras-4001 In Combination, Eras-0015, Eras-0015 In Combination, Temozolomide, Trametinib, Dacarbazine, Naporafenib, Trametinib, Naporafenib, Eras-801, Encorafenib, Palbociclib, Cetuximab, Eras-007, Eras-601, Eras-007, Pembrolizumab, Cetuximab, Eras-601. These drug candidates are in various stages of clinical development as the company works toward FDA approval.