Record First Quarter Net Revenue for HEPLISAV-B
Dynavax reported its highest ever first quarter net revenue for HEPLISAV-B at $65 million, which was a 36% increase compared to the previous year. This performance sets the company on track to achieve the top half of their full-year guidance range of net product sales between $305 million and $325 million.
Expansion of Development Pipeline
Dynavax is advancing its development pipeline with significant clinical trial milestones for its shingles and plague vaccine programs. Additionally, new programs for pandemic influenza and Lyme disease vaccines were announced, leveraging their CpG-1018 adjuvant technology.
Strong Market Position for HEPLISAV-B
HEPLISAV-B's estimated U.S. market share rose to 43% in Q1, up from 41% in the same period last year, driven by broad-based gains and consistent annual market share increases across major retail customers.
Positive Financial Outlook
Dynavax expects adjusted EBITDA to be at least $75 million for the full year 2025, demonstrating their ability to grow adjusted EBITDA at more than two times the rate of product revenue.