UP0 Stock Chart & Stats
€21.53
-€0.38(-1.59%)
At close: 4:00 PM EDT
€21.53
-€0.38(-1.59%)
Day’s Range― - ―
52-Week Range€12.80 - €34.00
Previous CloseN/A
Volume0.00
Average Volume (3M)12.00
Market Cap
€1.30B
Enterprise Value€4.31K
Total Cash (Recent Filing)€292.00M
Total Debt (Recent Filing)€1.20B
Price to Earnings (P/E)―
Beta0.87
Next Earnings
Nov 04, 2026EPS Estimate
-0.75Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-5.84
Shares Outstanding98,588,875
10 Day Avg. Volume37
30 Day Avg. Volume12
Financial Highlights & Ratios
PEG Ratio0.54
Price to Book (P/B)-28.35
Price to Sales (P/S)3.37
P/FCF Ratio-4.80
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price Target
€23.66Price Target Upside9.88% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering20
EPS Forecast (FY)-3.45
Revenue Forecast (FY)€647.29M
Bulls Say, Bears Say
Bulls Say
Revenue Growth And High Gross MarginsUltragenyx is scaling its commercial base while retaining very high gross profitability, indicating strong economics in its specialty rare-disease products. Continued revenue expansion gives the company a foundation to absorb operating investments and improve future earnings if expenses become more disciplined.
Broad Commercial Portfolio And Geographic ExpansionMultiple marketed therapies and growth across several regions reduce reliance on a single product and demonstrate commercial execution in specialty markets. Evkeeza's 50% year-over-year growth and expanding patient access add a potentially durable contributor to the existing franchise.
GENGLYCOS Accelerated FDA ApprovalThe GENGLYCOS approval expands Ultragenyx's commercial rare-disease platform with a gene therapy addressing an ultra-rare condition. The reported Phase 3 reduction in cornstarch requirements supports launch potential, while long-term follow-up can build additional evidence.
Bears Say
Deep Operating Losses And Persistent Cash BurnUltragenyx's strong gross margins have not yet translated into sustainable profitability because operating costs remain substantially higher than gross profit. Persistent cash consumption can require continued external funding and limits the resources available for pipeline investment.
Negative Equity And Elevated LeverageNegative equity and the reported debt increase materially weaken financial flexibility and raise refinancing risk. A more leveraged balance sheet can constrain capital allocation, make the company more sensitive to execution setbacks, and increase dependence on successful product growth.
Late-stage Pipeline Setback And Clinical UncertaintyThe ASPIRE failure removes support for an important late-stage pipeline opportunity and raises questions about future development productivity in Angelman syndrome. Reassessing the program and cutting expenses may help preserve cash, but also narrows potential long-term growth.
Ultragenyx Pharmaceutical News
UP0 FAQ
What was Ultragenyx Pharmaceutical’s price range in the past 12 months?
Ultragenyx Pharmaceutical lowest stock price was €12.79 and its highest was €34.00 in the past 12 months.
What is Ultragenyx Pharmaceutical’s market cap?
Ultragenyx Pharmaceutical’s market cap is €1.30B.
When is Ultragenyx Pharmaceutical’s upcoming earnings report date?
Ultragenyx Pharmaceutical’s upcoming earnings report date is Nov 04, 2026 which is in 56 days.
How were Ultragenyx Pharmaceutical’s earnings last quarter?
Ultragenyx Pharmaceutical released its earnings results on Aug 04, 2026. The company reported -€0.777 earnings per share for the quarter, beating the consensus estimate of -€1.051 by €0.274.
Is Ultragenyx Pharmaceutical overvalued?
According to Wall Street analysts Ultragenyx Pharmaceutical’s price is currently Undervalued.
Does Ultragenyx Pharmaceutical pay dividends?
Ultragenyx Pharmaceutical does not currently pay dividends.
What is Ultragenyx Pharmaceutical’s EPS estimate?
Ultragenyx Pharmaceutical’s EPS estimate is -0.75.
How many shares outstanding does Ultragenyx Pharmaceutical have?
Ultragenyx Pharmaceutical has 98,588,875 shares outstanding.
What happened to Ultragenyx Pharmaceutical’s price movement after its last earnings report?
Ultragenyx Pharmaceutical reported an EPS of -€0.777 in its last earnings report, beating expectations of -€1.051. Following the earnings report the stock price went up 5.899%.
Which hedge fund is a major shareholder of Ultragenyx Pharmaceutical?
Currently, no hedge funds are holding shares in DE:UP0
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Ultragenyx Pharmaceutical Stock Smart Score
Neutral
1
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5
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7
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9
10
Analyst Consensus
Moderate Buy
Average Price Target:
€23.66 (9.88% Upside)
€23.66 (9.88% Upside)
Blogger Sentiment
Bullish
DE:UP0 Sentiment 74%
Sector Average 60%
Sector Average 60%
Insider Transactions
Sold Shares
Worth €360.3K over
the Last 3 Months
the Last 3 Months
News Sentiment
Very Bearish
Bullish news 11%
Bearish news 89%
Bearish news 89%
Technicals
SMA
Negative
20 days / 200 days
Momentum
-52.77%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
-3.24%
Trailing 12-Months
Learn more about TipRanks Smart Score
Company Description
Ultragenyx Pharmaceutical
Ultragenyx Pharmaceutical Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing innovative treatments for rare and ultra-rare genetic conditions. Its operations span North America, Europe, and other international markets. The company's portfolio of marketed biologic products addresses several serious diseases. This includes Crysvita (burosumab), an antibody that targets fibroblast growth factor 23, used to treat X-linked hypophosphatemia and tumor-induced osteomalacia. Mepsevii offers enzyme replacement therapy for both pediatric and adult patients suffering from Mucopolysaccharidosis VII. Dojolvi is available for individuals with long-chain fatty acid oxidation disorders, while Evkeeza (evinacumab) provides a treatment option for homozygous familial hypercholesterolemia. Ultragenyx also boasts a robust pipeline of investigational therapies. Notable candidates include DTX401, an adeno-associated virus 8 (AAV8) gene therapy for glycogen storage disease type Ia, and DTX301, another AAV8 gene therapy aimed at ornithine transcarbamylase deficiency. Other promising developments feature UX143, a human monoclonal antibody for osteogenesis imperfecta; GTX-102, an antisense oligonucleotide designed for Angelman syndrome; UX701, targeting Wilson disease; and UX053, in development for glycogen storage disease type III. To advance its research and development efforts, Ultragenyx Pharmaceutical Inc. maintains strategic collaboration and licensing agreements with numerous partners, such as Kyowa Kirin Co., Ltd., Saint Louis University, REGENXBIO Inc., Bayer Healthcare LLC, GeneTx, Mereo, University of Pennsylvania, Arcturus Therapeutics Holdings Inc., Solid Biosciences Inc., and Daiichi Sankyo Co., Ltd. The company was founded in 2010 and operates from its headquarters in Novato, California.
UP0 Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
Positive overall: the call highlighted record quarterly revenue, broad-based product growth (including Evkeeza +50% YoY), expanding patient counts across multiple geographies, improving cash consumption versus Q1, and clear near-term catalysts (two PDUFAs and a pivotal readout). Management articulated a credible path to profitability in 2027 with expense discipline and potential non-dilutive PRV monetization. Offsetting risks include a sizable operating loss and expense run-rate, reliance on binary regulatory outcomes, an unmet primary outcome for setrusumab requiring possible new trials, and readout/regulatory uncertainty for GTX-102, but these are framed as manageable and addressable within management's plan.View all DE:UP0 earnings summariesUP0 Stock 12 Month Forecast
Average Price Target
€23.66
▲(9.88% Upside)
Technical Analysis
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