Protagonist Therapeutics stock analysis
Protagonist Therapeutics (PGF) Stock Price & Analysis
PGF Stock Chart & Stats
- Day’s Range
- EUR 74.50 - EUR 75.00
- 52-Week Range
- EUR 71.50 - EUR 81.00
- Previous Close
- EUR 75.00
- Volume
- N/A
- Average Volume (3M)
- 0
- Market Cap
- EUR 7.96B
- Enterprise Value
- EUR 9.31B
- Total Cash (Recent Filing)
- EUR 800.06M
- Total Debt (Recent Filing)
- EUR 8.63M
- Price to Earnings (P/E)
- 26.4
- Beta
- 0.18
- Next Earnings
- Mar 02, 2027 (Est.)
- EPS Estimate
- -0.13
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Strong TTM Revenue And Profitability
The sharp TTM improvement in revenue and profitability indicates that partnered program activity can generate substantial economic value when milestones or collaboration revenues are recognized. If operating performance remains strong, high margins could support continued research investment and strengthen funding flexibility.
Positive Cash Generation
Positive operating and free cash flow provides internal funding for clinical development and reduces reliance on external capital in the near term. Cash conversion slightly above net income also supports the quality of reported earnings, giving the company greater flexibility across development priorities.
Conservative Balance Sheet
Minimal leverage and a substantial equity base give Protagonist meaningful financial flexibility as it advances peptide-based medicines. The conservative capital structure limits interest and refinancing pressure, allowing more resources to remain available for clinical programs, partnerships, and other long-term priorities.
Bears Say
Revenue And Earnings Volatility
The substantial year-to-year swings show that current profitability is not yet a consistently demonstrated operating trend. Because biotech results can depend on the timing of collaboration and development milestones, uneven earnings make future cash generation and resource planning less predictable over the next several periods.
Limited Cash-flow Consistency
Although recent cash generation is positive, the decline in TTM free cash flow and history of negative cash flow indicate that internally generated funding may not remain stable. This variability can complicate clinical investment planning and increase sensitivity to the timing of partnership-related receipts.
Dependence On Collaboration-based Revenue
The collaboration-led model exposes revenue to the timing and progress of partnered clinical programs rather than a recurring commercial product base. Payments may be uneven because upfront, milestone, and royalty streams depend on development, regulatory, and commercialization achievements.
Protagonist Therapeutics News
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Protagonist Therapeutics Stock Smart Score
Company Description
Protagonist Therapeutics
Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company's pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for the management of polycythemia vera, hereditary hemochromatosis, and other blood-related ailments. Also in Phase II development is PN-943, an oral peptide engineered as a specific antagonist of alpha-4-beta-7 integrin, intended for addressing inflammatory bowel disease (IBD). Furthermore, they are progressing PN-235, an orally administered antagonist specifically targeting the interleukin-23 receptor, designed for both IBD and various non-IBD therapeutic applications. Protagonist Therapeutics maintains a licensing and collaborative agreement with Janssen Biotech, Inc. Founded in 2006, the company's headquarters are located in Newark, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Dinesh V. Patel
- Employees
- 132
- Website
- www.protagonist-inc.com
- Address
- 7707 Gateway Boulevard, Newark, CA, 94560, US
Protagonist Therapeutics (PGF) Earnings & Revenues
PGF Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 3 | 7 | 9 |
| Technical Analysis | 2 | 1 | 4 |
| Moving Averages | 1 | 6 | 5 |













