Operating Cash BurnPersistent negative operating cash flow signals the core business does not generate sustainable cash, forcing reliance on equity/debt raises or reserves. This constrains strategic choices, risks dilution or covenant pressure, and limits ability to invest in commercialization or clinical scale-up over months.
Margin CollapseA negative gross profit represents a structural pricing, cost, or product-mix problem that erodes unit economics. If unresolved, margins will undermine ability to cover fixed costs, fund R&D or training, and sustain clinic support—threatening long-term viability of the product business model.
Recent Revenue DeteriorationThe shift from prior growth to sharp recent declines suggests demand, reimbursement, or commercial execution issues. Falling top-line, alongside fixed cost commitments, magnifies losses and complicates recovery; sustained declines would impair scale economics and market penetration prospects.