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Cytosorbents Corp (CTSO)
NASDAQ:CTSO
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Cytosorbents (CTSO) AI Stock Analysis

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CTSO

Cytosorbents

(NASDAQ:CTSO)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
$0.50
▼(-30.56% Downside)
Cytosorbents' overall stock score is primarily impacted by its challenging financial performance, characterized by high leverage and negative cash flows. Technical indicators suggest bearish momentum, and valuation metrics are weak due to ongoing losses. While the earnings call highlighted some positive developments, regulatory hurdles and increased expenses pose risks.
Positive Factors
Product Sales Growth
The 9% YoY growth in product sales indicates strong demand and market acceptance, which supports long-term revenue potential and business expansion.
German Market Expansion
Successful reorganization in Germany, leading to 22% growth, suggests effective market strategies and potential for further international expansion.
Strong Gross Margin
A strong gross margin of 71% reflects efficient cost management and operational effectiveness, supporting long-term profitability potential.
Negative Factors
Regulatory Challenges
Regulatory setbacks for DrugSorb ATR could delay market entry and revenue generation, impacting long-term growth prospects.
High Operating Expenses
Rising operating expenses, up 3%, strain profitability and could hinder efforts to achieve breakeven, affecting financial stability.
Negative Cash Flow
Negative cash flows pose liquidity challenges, limiting the company's ability to invest in growth and manage debt, affecting long-term viability.

Cytosorbents (CTSO) vs. SPDR S&P 500 ETF (SPY)

Cytosorbents Business Overview & Revenue Model

Company DescriptionCytosorbents Corporation (CTSO) is a medical technology company focused on developing and commercializing innovative products for critical care and cardiac surgery. The company specializes in blood purification technology, particularly through its flagship product, CytoSorb, which is designed to remove harmful substances from the bloodstream during severe inflammatory conditions. Cytosorbents operates primarily in the healthcare sector, targeting hospitals and medical facilities that require advanced treatment options for patients experiencing life-threatening conditions.
How the Company Makes MoneyCytosorbents generates revenue primarily through the sale of its CytoSorb devices and related products to hospitals and healthcare providers. The company employs a direct sales model in certain markets, while also working with distributors and partners to expand its reach. Key revenue streams include the sale of disposable CytoSorb cartridges, which are used in conjunction with the device for blood purification during critical care treatments. The company has established significant partnerships with medical institutions and research organizations, which not only enhance its product visibility but also facilitate clinical studies that can lead to broader adoption of its technologies. Additionally, Cytosorbents may explore opportunities for reimbursement from healthcare payers, further contributing to its earnings potential.

Cytosorbents Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 13, 2025
Earnings Call Sentiment Neutral
The earnings call reflects a mixed sentiment. While there are strong sales growth, successful restructuring efforts, and positive clinical data, the regulatory challenges for DrugSorb ATR and increased operating expenses pose significant concerns.
Q2-2025 Updates
Positive Updates
Product Sales Growth
Cytosorbents reported product sales of $9.6 million in Q2 2025, representing a 9% year-over-year increase and a 4% increase on a constant currency basis.
German Commercial Team Reorganization Success
The German commercial team saw a 22% year-over-year and sequential growth, indicating successful reorganization and strategic realignment.
Strong Gross Margin
Gross margin performance remained solid at approximately 71%, indicating strong operational efficiency.
Positive Data on CytoSorb for Sepsis Treatment
CytoSorb demonstrated significant reductions in severe CABG-related bleeding and large transfusion events in clinical settings, strengthening its clinical utility.
Net Income Achievement
The company reported a net income of $1.9 million for Q2 2025, compared to a net loss of $4.3 million in the prior year.
Negative Updates
Regulatory Challenges for DrugSorb ATR
The FDA issued a denial letter for the de novo request for DrugSorb ATR, and Health Canada issued a notice of refusal, leading to ongoing appeals processes.
Operating Expenses Increase
Q2 operating expenses were $10.4 million, up approximately 3% from the prior year, due to unique operating and strategic charges.
Adjusted Net Loss
The adjusted net loss for the quarter was $3.7 million, compared to $2.8 million in the prior year, indicating ongoing financial pressures.
Company Guidance
In the second quarter of 2025, Cytosorbents Corp reported product sales of $9.6 million, reflecting a 9% year-over-year increase and a 4% increase on a constant currency basis. The company's gross margin held steady at approximately 71%, although there was a slight decline from the previous year's 73.5%, attributed primarily to inventory write-offs. The German commercial team saw notable improvements, with a 22% growth year-over-year and sequentially, contributing to the overall performance. Operating expenses increased slightly due to unique strategic charges, but the company remains focused on reducing core business operating costs to drive towards breakeven by the end of the year. Cytosorbents also reported a net income of $1.9 million for the quarter, but when adjusted for currency changes and non-cash items, the adjusted net loss was $3.7 million. The company continues to prepare for a potential North American launch of DrugSorb ATR, anticipating regulatory decisions from both the FDA and Health Canada by the end of 2025.

Cytosorbents Financial Statement Overview

Summary
Cytosorbents faces significant financial challenges, with consistent losses and high leverage. Despite strong gross profit margins, profitability is hindered by high operating expenses and negative cash flows, posing risks to financial stability.
Income Statement
45
Neutral
Cytosorbents has shown a slight improvement in revenue growth with a TTM growth rate of 2.37%. However, the company continues to face significant profitability challenges, as indicated by negative net profit and EBIT margins. The gross profit margin remains strong at 72.57%, suggesting efficient cost management at the production level, but overall profitability is hindered by high operating expenses.
Balance Sheet
40
Negative
The company's balance sheet reflects high leverage with a debt-to-equity ratio of 2.34, indicating a reliance on debt financing. The return on equity is negative, highlighting ongoing losses. The equity ratio stands at 24.14%, suggesting a moderate level of equity financing relative to total assets, but the high debt levels pose a risk to financial stability.
Cash Flow
35
Negative
Cytosorbents is experiencing negative operating and free cash flows, with a declining free cash flow growth rate of -24.67% in the TTM period. The operating cash flow to net income ratio is close to 1, indicating that cash flow generation is in line with net losses, but the overall cash flow situation remains weak, posing liquidity challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue33.48M35.59M31.08M29.36M40.11M39.45M
Gross Profit24.30M25.13M21.95M15.40M29.06M28.40M
EBITDA-9.87M-19.26M-27.88M-32.77M-21.62M-9.71M
Net Income-9.75M-20.72M-29.25M-32.81M-24.56M-7.84M
Balance Sheet
Total Assets47.99M47.37M53.26M63.23M89.52M89.95M
Cash, Cash Equivalents and Short-Term Investments10.20M3.28M14.13M22.14M52.14M71.42M
Total Debt27.06M26.89M18.31M18.25M13.82M1.03M
Total Liabilities36.40M36.26M29.99M27.86M26.94M10.73M
Stockholders Equity11.59M11.11M23.28M35.38M62.58M79.22M
Cash Flow
Free Cash Flow-10.29M-14.71M-22.59M-34.69M-18.29M-7.29M
Operating Cash Flow-9.78M-14.43M-21.66M-28.23M-14.01M-5.61M
Investing Cash Flow-601.55K-669.43K-936.24K-6.46M-4.28M-1.68M
Financing Cash Flow6.90M9.33M14.47M4.96M715.20K66.35M

Cytosorbents Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.72
Price Trends
50DMA
0.89
Negative
100DMA
0.96
Negative
200DMA
0.99
Negative
Market Momentum
MACD
-0.05
Positive
RSI
29.89
Positive
STOCH
6.53
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CTSO, the sentiment is Negative. The current price of 0.72 is below the 20-day moving average (MA) of 0.82, below the 50-day MA of 0.89, and below the 200-day MA of 0.99, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 29.89 is Positive, neither overbought nor oversold. The STOCH value of 6.53 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CTSO.

Cytosorbents Risk Analysis

Cytosorbents disclosed 39 risk factors in its most recent earnings report. Cytosorbents reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cytosorbents Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$92.75M11.984.92%1.43%-20.12%
64
Neutral
$69.05M-5.71%-13.79%-132.21%
52
Neutral
$103.88M-20.78-9.80%15.16%-39.18%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$96.28M-1.97-77.26%-9.59%8.78%
45
Neutral
$88.66M-2.52-87.61%14.04%-0.65%
41
Neutral
$49.66M-4.34-68.84%-7.81%65.39%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CTSO
Cytosorbents
0.72
-0.21
-22.47%
FONR
Fonar
14.97
0.04
0.27%
NSPR
InspireMD
1.68
-0.78
-31.71%
XTNT
Xtant Medical Holdings
0.76
0.24
46.91%
SRTS
Sensus Healthcare
4.34
-2.71
-38.44%
HYPR
Hyperfine
1.03
0.13
14.44%

Cytosorbents Corporate Events

Cytosorbents Corp’s Latest Study Update: A Game Changer in Critical Care?
Oct 27, 2025

Study Overview: The CytOSorb TreatMent Of Critically Ill PatientS Registry is an international observational study aimed at creating a comprehensive data repository to monitor the use of the CytoSorb device in real-world critical care settings. This registry seeks to enhance the quality of patient care by providing a scientifically-based resource for measuring and improving treatment outcomes in conditions such as septic shock, acute respiratory distress syndrome, and more.

CytoSorbents’ STAR Registry: A Closer Look at the Latest Clinical Study Update
Oct 27, 2025

The Safe and Timely Antithrombotic Removal (STAR) Registry is an international observational study conducted by CytoSorbents Corp. Its primary aim is to document real-world clinical use and outcomes of the CytoSorb device, specifically for removing antithrombotic agents in acute hospital settings. This study is significant as it addresses critical conditions such as surgical and postoperative hemorrhage, providing insights into the device’s effectiveness and safety.

Delistings and Listing ChangesRegulatory Filings and Compliance
Cytosorbents Faces Nasdaq Non-Compliance Notice
Negative
Oct 3, 2025

On October 2, 2025, CytoSorbents Corporation received a notice from Nasdaq for non-compliance with the Minimum Bid Price Requirement, as its stock price remained below $1.00 for 30 consecutive business days. The company has until March 31, 2026, to regain compliance by ensuring its stock price meets or exceeds $1.00 for at least 10 consecutive days. Failure to comply could lead to an additional compliance period if an acceptable plan is presented to Nasdaq. The company is actively monitoring its stock price and exploring options to meet the requirement.

The most recent analyst rating on (CTSO) stock is a Hold with a $1.00 price target. To see the full list of analyst forecasts on Cytosorbents stock, see the CTSO Stock Forecast page.

Cytosorbents Corp Q2 2025 Earnings Call Highlights
Aug 13, 2025

Cytosorbents Corp’s recent earnings call reflected a balanced sentiment, highlighting positive growth in product sales and strategic advancements in the German market, while also addressing significant regulatory hurdles with the DrugSorb ATR product. Despite an increase in operational costs, the company remains optimistic about its appeal processes and potential future growth.

CytoSorbents Reports Positive Q2 2025 Financial Results
Aug 8, 2025

CytoSorbents Corporation is a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery through its innovative blood purification technologies. The company specializes in removing toxic substances from blood, offering solutions for critical illnesses such as sepsis and septic shock.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 06, 2025