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C4 Therapeutics (CCCC)
NASDAQ:CCCC
US Market
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C4 Therapeutics (CCCC) AI Stock Analysis

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CCCC

C4 Therapeutics

(NASDAQ:CCCC)

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Neutral 48 (OpenAI - Gpt-5.6Sol)
Rating:48Neutral
Price Target:
$3.50
▼(-17.45% Downside)
Action:Reiterated
Date:08/11/26
The score is primarily held back by weak financial performance—declining revenue, large ongoing losses, and significant cash burn. Technical indicators are broadly neutral with slightly soft momentum, offering limited near-term support. Corporate events are a relative positive (clinical progress and collaboration/cash runway), but valuation remains hard to support given negative earnings and no dividend yield provided.
Positive Factors
Targeted protein degradation platform
The TORPEDO platform gives C4 Therapeutics a differentiated approach to drug discovery by targeting disease-causing proteins for degradation. If internal programs validate the technology, the platform could support multiple oncology and therapeutic candidates and create repeatable partnering opportunities over time.
Negative Factors
Declining revenue and severe losses
Falling revenue on an already small base, combined with a deeply negative net margin, shows that the current operating model is not yet self-sustaining. Persistent losses make future profitability dependent on successful clinical progress, partnering economics, or materially improved revenue generation.
Read all positive and negative factors
Positive Factors
Negative Factors
Targeted protein degradation platform
The TORPEDO platform gives C4 Therapeutics a differentiated approach to drug discovery by targeting disease-causing proteins for degradation. If internal programs validate the technology, the platform could support multiple oncology and therapeutic candidates and create repeatable partnering opportunities over time.
Read all positive factors

C4 Therapeutics (CCCC) vs. SPDR S&P 500 ETF (SPY)

C4 Therapeutics Business Overview & Revenue Model

Company Description
C4 Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing innovative therapeutic candidates. Its core strategy involves degrading proteins implicated in disease, addressing a range of conditions incl...
How the Company Makes Money
C4 Therapeutics primarily generates revenue through collaboration and license agreements with larger pharmaceutical companies, rather than through product sales (as it is clinical-stage). Under these arrangements, the company can earn (1) upfront ...

C4 Therapeutics Financial Statement Overview

Summary
Weak operating profile: TTM revenue declined ~18.5% and profitability remains deeply negative (net margin ~-298%), with persistent losses. Balance-sheet leverage is relatively modest (debt-to-equity ~0.25), but cash burn is significant (TTM operating cash flow about -$84.9M; free cash flow about -$85.4M), raising ongoing funding/runway dependence.
Income Statement
23
Negative
Balance Sheet
54
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue35.04M35.95M35.58M20.76M31.10M45.78M
Gross Profit33.24M27.97M35.58M13.02M31.10M45.78M
EBITDA-98.31M-102.91M-103.37M-122.10M-124.28M-80.25M
Net Income-101.42M-104.99M-105.32M-132.49M-128.18M-83.89M
Balance Sheet
Total Assets359.40M359.07M349.60M376.45M430.84M506.76M
Cash, Cash Equivalents and Short-Term Investments253.66M248.54M244.90M253.68M276.15M309.28M
Total Debt56.86M59.98M65.76M70.98M87.15M42.88M
Total Liabilities112.14M102.49M133.62M130.34M141.61M117.16M
Stockholders Equity247.26M256.59M215.99M246.11M289.23M389.61M
Cash Flow
Free Cash Flow-85.39M-99.30M-65.34M-108.55M-111.44M-88.24M
Operating Cash Flow-84.87M-98.69M-65.16M-106.84M-105.94M-86.97M
Investing Cash Flow-75.31M-8.60M-51.27M158.35M58.42M-189.34M
Financing Cash Flow160.63M126.40M45.34M45.49M1.15M171.40M

C4 Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.24
Price Trends
50DMA
3.75
Negative
100DMA
3.74
Negative
200DMA
3.09
Positive
Market Momentum
MACD
-0.14
Positive
RSI
36.78
Neutral
STOCH
21.77
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CCCC, the sentiment is Negative. The current price of 4.24 is above the 20-day moving average (MA) of 3.72, above the 50-day MA of 3.75, and above the 200-day MA of 3.09, indicating a neutral trend. The MACD of -0.14 indicates Positive momentum. The RSI at 36.78 is Neutral, neither overbought nor oversold. The STOCH value of 21.77 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CCCC.

C4 Therapeutics Risk Analysis

C4 Therapeutics disclosed 73 risk factors in its most recent earnings report. C4 Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

C4 Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$2.32B-54.38-35.91%35.38%
53
Neutral
$50.86M-1.34248.50%36.06%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$417.06M-3.39-45.45%2.33%36.86%
45
Neutral
$39.77M-1.65-60.32%71.26%
45
Neutral
$212.90M-2.65-136.45%-1475.42%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CCCC
C4 Therapeutics
3.39
0.78
29.89%
SLS
SELLAS Life Sciences Group
11.49
9.77
568.02%
MCRB
Seres Therapeutics
4.00
-12.52
-75.79%
ELDN
Eledon Pharmaceuticals
2.62
0.02
0.77%
TVGN
Tevogen Bio Holdings
7.81
-33.96
-81.30%
ACTU
Actuate Therapeutics, Inc.
0.98
-6.11
-86.16%

C4 Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
C4 Therapeutics Shareholders Back Directors, Pay and Auditors
Positive
Jun 24, 2026
On June 24, 2026, C4 Therapeutics, Inc. held its Annual Meeting of Stockholders, at which shareholders elected Andrew J. Hirsch, Stephen Fawell, Ph.D., and Utpal Koppikar as Class III directors to serve until the 2029 annual meeting. Stockholders ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 11, 2026