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Dexamethasone, Cemsidomide
Multiple Myeloma, Relapsed/Refractory Multiple Myeloma
Phase II
Recruiting
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
Dec 09, 2025
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Cetuximab, Trametinib, Cft1946
Crc, Atc, Melanoma, Solid Tumors, Nsclc
Phase I
Active Not Recruiting
A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors
Dec 06, 2022
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Cft8634
Synovial Sarcoma, Soft Tissue Sarcoma
Phase I
Terminated
A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors
Apr 23, 2022
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Dexamethasone Oral, Cemsidomide
Lymphoma, Non-Hodgkin's, Multiple Myeloma
Phase I
Active Not Recruiting
Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma
Feb 12, 2021
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does C4 Therapeutics (CCCC) have in its pipeline
CCCC is currently developing the following drugs: Dexamethasone, Cemsidomide, Elranatamab, Cemsidomide, Cetuximab, Trametinib, Cft1946. These drug candidates are in various stages of clinical development as the company works toward FDA approval.