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Bioline RX Ltd Sponsored ADR (BLRX)
NASDAQ:BLRX
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Bioline RX Ltd Sponsored ADR (BLRX) AI Stock Analysis

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BLRX

Bioline RX Ltd Sponsored ADR

(NASDAQ:BLRX)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
$3.50
▼(-6.91% Downside)
The overall stock score is primarily influenced by the company's financial performance and technical analysis. Despite significant revenue growth, ongoing profitability challenges and high leverage weigh heavily on the score. The bearish technical indicators further contribute to a cautious outlook. Valuation concerns, highlighted by a negative P/E ratio, also impact the score. While the earnings call provided some positive insights, it was not included in the weighted calculation.
Positive Factors
Pipeline Expansion
Expanding the pipeline with new assets in oncology and rare diseases enhances long-term growth potential and diversifies revenue streams.
Cash Runway Extension
A strong cash position ensures operational stability and supports strategic initiatives, reducing the risk of financial distress.
Cost Management
Effective cost management improves financial efficiency, allowing the company to allocate resources towards growth and innovation.
Negative Factors
Net Loss
Ongoing net losses indicate challenges in achieving profitability, which may affect long-term financial sustainability and investor confidence.
High Leverage
High leverage can strain financial flexibility and increase risk, especially if revenue growth does not offset interest obligations.
Royalty Revenue Dependency
Dependence on royalties from partners can lead to revenue volatility, impacting financial predictability and strategic planning.

Bioline RX Ltd Sponsored ADR (BLRX) vs. SPDR S&P 500 ETF (SPY)

Bioline RX Ltd Sponsored ADR Business Overview & Revenue Model

Company DescriptionBioLineRx Ltd., a clinical-stage biopharmaceutical development company, focuses on oncology. The company develops Motixafortide, a peptide, which has completed Phase 3 clinical trials for the treatment of autologous stem cell mobilization and Phase 2a clinical trials for the treatment of pancreatic cancer; and that is in Phase 2 clinical trials for the treatment of metastatic pancreatic adenocarcinoma patients, and Phase 1b clinical trials in patients with acute respiratory distress syndrome secondary to COVID-19 and other respiratory viral infections, as well as for the treatment of solid tumors and acute myeloid leukemia. It is also developing AGI-134, an immuno-oncology agent, which is in Phase 1/2a clinical trials for the treatment of solid tumors; and BL-5010, a customized, proprietary, pen-like applicator for the non-surgical removal of skin lesions. The company has collaboration agreement with MSD for the cancer immunotherapy field; MD Anderson Cancer Center to investigate the combination of Motixafortide with KEYTRUDA (pembrolizumab) in pancreatic cancer; and licensing arrangement with Perrigo Company plc for over-the-counter sale of BL-5010. BioLineRx Ltd. was incorporated in 2003 and is headquartered in Hevel Modi'in, Israel.
How the Company Makes MoneyBioline RX generates revenue primarily through the development and commercialization of its therapeutic products. The company may receive revenue from milestone payments associated with partnerships and collaborations with larger pharmaceutical companies, as well as potential royalties from product sales once they are commercialized. Additionally, Bioline RX may engage in research agreements or licensing deals that provide upfront payments and future earnings based on the success of their drug candidates. Significant partnerships with established healthcare companies can also contribute to the company’s financial growth, especially if these collaborations lead to successful clinical trials and subsequent market approvals.

Bioline RX Ltd Sponsored ADR Earnings Call Summary

Earnings Call Date:Aug 14, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Dec 01, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in pipeline expansion and positive clinical trial outcomes, paired with successful cost management strategies. However, financial challenges persist, as evidenced by the net loss and dependency on royalty revenues. While the highlights suggest optimism for future growth, the financial and operational challenges maintain a balanced outlook.
Q2-2025 Updates
Positive Updates
Progress in Pipeline Expansion
BioLineRx is making excellent progress in evaluating promising early-stage assets in oncology and rare diseases to support pipeline expansion, targeting the execution of a transaction this year.
Collaborative Study Success
The PDAC trial in collaboration with Columbia University showed a partial response rate of 64%, significantly higher than the historical rate of 23%. Additionally, 91% of patients exhibited disease control compared to the historical rate of 48%.
Positive ASCO Presentation
New data from a pancreatic cancer study was presented at ASCO, showing a significant increase in CD8-positive T cell density in tumors, suggesting potential to overcome tumor immunosuppressive mechanisms.
Extended Cash Runway
BioLineRx ended Q2 2025 with $28.2 million in cash and equivalents, extending their cash runway into the first half of 2027, compared to previous guidance through the second half of 2026.
Significant Reduction in Operating Expenses
The company reduced its operating cash burn by more than 70% after restructuring and shutting down U.S. operations, transforming into a leaner organization.
Negative Updates
Net Loss in Q2 2025
BioLineRx reported a net loss of $3.9 million for the second quarter of 2025, compared to a net income of $0.5 million in the same period of 2024.
Challenges in Study Progression
Questions remain about the potential for accelerated approval based on interim analysis of the PDAC study, with skepticism about achieving accelerated approval from a 40% PFS event rate.
Royalty Revenue Dependency
BioLineRx reported total revenues of $0.3 million from royalties paid by Ayrmid, reflecting a dependency on partner commercialization efforts.
Company Guidance
During the BioLineRx Second Quarter 2025 Financial Results Conference Call, the company provided several key metrics and guidance updates. They reported $1.7 million in APHEXDA sales, resulting in $0.3 million of royalty revenues. BioLineRx is well-financed, with cash and equivalents of $28.2 million, sufficient to fund operations into the first half of 2027, extending their previous guidance. Research and development expenses were $2.3 million, and the net loss for the quarter was $3.9 million. The company is actively pursuing the acquisition of new early-stage assets in oncology and rare diseases, with a target to execute a transaction by the end of the year. BioLineRx also highlighted promising clinical data and ongoing trials, including a Phase IIb PDAC trial and two Phase I trials for sickle cell disease, which could potentially yield long-term milestones and royalties.

Bioline RX Ltd Sponsored ADR Financial Statement Overview

Summary
BioLine RX Ltd shows significant revenue growth and improved EBITDA margin, indicating operational efficiency. However, the company still faces challenges with negative net income, high leverage, and weak cash flow from operations, which impact financial stability.
Income Statement
25
Negative
The company has shown significant revenue growth from 2023 to 2024, with a surge from $4.8 million to $28.94 million. However, the net profit margin remains negative, indicating ongoing profitability challenges. The negative EBIT margin highlights persistent operating losses, though the transition from a negative to a positive EBITDA margin suggests some improvement in operational efficiency.
Balance Sheet
40
Negative
The debt-to-equity ratio is relatively high at 1.12, indicating a heavy reliance on debt financing which could pose risks in terms of financial stability. The equity ratio has decreased, reflecting a reduced capacity to cover assets with equity. Despite these challenges, the company maintains a positive stockholders’ equity, indicating some level of financial health.
Cash Flow
30
Negative
The free cash flow remains negative, although there is a notable increase in financing inflows, reflecting the company's ability to raise funds. However, the operating cash flow to net income ratio is negative, suggesting that cash generation from operations is weak, which could impact long-term sustainability.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue28.94M4.80M0.000.000.00
Gross Profit19.68M1.11M0.000.000.00
EBITDA3.92M-57.09M-28.50M-24.07M-27.59M
Net Income-9.22M-60.61M-24.95M-27.05M-30.02M
Balance Sheet
Total Assets38.91M63.92M76.38M81.39M47.29M
Cash, Cash Equivalents and Short-Term Investments19.56M42.99M51.08M57.13M22.59M
Total Debt15.04M11.59M12.32M4.65M7.68M
Total Liabilities25.45M50.70M25.54M13.30M25.26M
Stockholders Equity13.46M13.22M50.84M68.09M22.03M
Cash Flow
Free Cash Flow-43.93M-22.91M-26.56M-23.67M-23.21M
Operating Cash Flow-43.87M-22.61M-26.24M-23.57M-23.21M
Investing Cash Flow29.37M1.44M4.01M-38.22M16.67M
Financing Cash Flow20.66M15.06M20.44M57.75M17.87M

Bioline RX Ltd Sponsored ADR Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.76
Price Trends
50DMA
3.86
Negative
100DMA
4.08
Negative
200DMA
4.27
Negative
Market Momentum
MACD
-0.02
Negative
RSI
47.87
Neutral
STOCH
55.91
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BLRX, the sentiment is Negative. The current price of 3.76 is below the 20-day moving average (MA) of 3.80, below the 50-day MA of 3.86, and below the 200-day MA of 4.27, indicating a bearish trend. The MACD of -0.02 indicates Negative momentum. The RSI at 47.87 is Neutral, neither overbought nor oversold. The STOCH value of 55.91 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BLRX.

Bioline RX Ltd Sponsored ADR Risk Analysis

Bioline RX Ltd Sponsored ADR disclosed 43 risk factors in its most recent earnings report. Bioline RX Ltd Sponsored ADR reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Bioline RX Ltd Sponsored ADR Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
45
Neutral
$16.00M-46.42%1.23%77.75%
45
Neutral
$20.36M-19.77-100.00%98.69%
44
Neutral
$24.35M-0.1160.64%
44
Neutral
$24.96M-0.4432.57%
38
Underperform
$19.56M-0.2318.73%
33
Underperform
$13.66M-1.1147.86%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BLRX
Bioline RX Ltd Sponsored ADR
3.76
-17.68
-82.46%
SYBX
Synlogic
1.70
0.21
14.09%
MBRX
Moleculin Biotech
0.49
-2.35
-82.75%
CTXR
Citius Pharmaceuticals
1.18
-11.33
-90.57%
CMMB
Chemomab Therapeutics
2.65
-3.63
-57.80%
PASG
Passage Bio
8.14
-5.86
-41.86%

Bioline RX Ltd Sponsored ADR Corporate Events

BioLineRx Reports Q2 2025 Financials and Strategic Updates
Aug 14, 2025

On August 14, 2025, BioLineRx Ltd. announced its financial results for the second quarter of 2025, highlighting a strong cash position with a runway extended into the first half of 2027. The company is actively evaluating opportunities to expand its pipeline in oncology and rare diseases, with ongoing discussions with potential partners. Clinical trials, including the CheMo4METPANC Phase 2b trial for metastatic pancreatic cancer and studies on sickle cell disease, are progressing. Financially, the company reported $0.3 million in revenues for the quarter, primarily from royalties, and a net loss of $3.9 million. The company has significantly reduced its expenses following a transaction with Ayrmid in late 2024.

BioLineRx Ltd. Approves Key Proposals at Annual Meeting
Jun 30, 2025

On June 29, 2025, BioLineRx Ltd. held its Annual General Meeting of Shareholders, where several key proposals were approved. These included the re-election of Dr. BJ Bormann and Dr. Raphael Hofstein as Class II directors, an increase in the company’s authorized share capital, the adoption of a renewed compensation policy for executives and directors, and the reappointment of Kesselman & Kesselman as the independent registered public accounting firm. These decisions are expected to strengthen the company’s governance and financial structure, potentially enhancing its market position and operational capabilities.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 16, 2025