Enrollment And AnalysisEnrollment into the ASPEN-BREAST trial is anticipated to begin soon, with an interim analysis planned to provide additional insights.
Market OpportunityData suggests that 50-70% of HER2+ breast cancer patients overexpress CD47, representing a large market opportunity for ALX Oncology if the study is successful.
Program PrioritizationManagement's decision to prioritize high-conviction programs is seen as prudent in the current financial environment.
Trial DesignALX Oncology is updating the design of its Phase 2 ASPEN-Breast study to enable a CD47 and HER2 biomarker-driven strategy, which could enhance the trial's effectiveness.