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Acurx Pharmaceuticals
(NASDAQ:ACXP)
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Rating:49Neutral
Price Target:
$1.50
▲(5.63% Upside)
Action:Reiterated
Date:05/14/26
Overall score reflects weak fundamentals (pre-revenue, ongoing losses and cash burn) and bearish technicals (price below key moving averages with negative MACD). These are partially offset by a constructive earnings update highlighting favorable FDA guidance, planned clinical progression, and IP strength, though funding needs remain a key risk.
Positive Factors
Compelling Phase II efficacy
High cure rates and no observed recurrence in Phase II materially strengthen the clinical profile and support the confirmatory evidence package for registration. Durable clinical differentiation versus competitors can reduce commercial and regulatory risk, aiding uptake and label arguments if confirmed in larger trials.
Negative Factors
Pre‑revenue and sustained net losses
Being pre‑revenue with persistent operating losses means the company lacks internal funding from sales and remains reliant on external capital. Even with improved loss metrics, ongoing negative margins limit financial flexibility and increase execution risk until commercial revenues materialize.
Read all positive and negative factors
Positive Factors
Negative Factors
Compelling Phase II efficacy
High cure rates and no observed recurrence in Phase II materially strengthen the clinical profile and support the confirmatory evidence package for registration. Durable clinical differentiation versus competitors can reduce commercial and regulatory risk, aiding uptake and label arguments if confirmed in larger trials.
Read all positive factors
Acurx Pharmaceuticals (ACXP) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$6.19M
Dividend YieldN/A
Average Volume (3M)1.14M
Price to Earnings (P/E)―
Beta (1Y)-0.28
Revenue GrowthN/A
EPS Growth68.70%
CountryUS
Employees4
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-4.91
Shares Outstanding4,297,738
10 Day Avg. Volume3,231,033
30 Day Avg. Volume1,135,368
Financial Highlights & Ratios
PEG Ratio<0.01
Price to Book (P/B)0.71
Price to Sales (P/S)0.00
P/FCF Ratio>-0.01
Enterprise Value/Market Cap-1.10
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/Ebitda0.91
Forecast
1Y Price Target
$17.00Price Target Upside1097.18% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering3
EPS Forecast (FY)-1.65
Revenue Forecast (FY)N/A
Acurx Pharmaceuticals Business Overview & Revenue Model
Company Description
Acurx Pharmaceuticals, Inc. functions as a clinical-stage biopharmaceutical firm focused on developing innovative antibiotic treatments for bacterial infections. The company's primary drug candidate is ibezapolstat, an antibiotic that utilizes a n...
How the Company Makes Money
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Acurx Pharmaceuticals Earnings Call Summary
Earnings Call Date:May 12, 2026
(Q1-2026)
| % Change Since: |
Next Earnings Date:Aug 14, 2026
Earnings Call Sentiment Positive
Overall the call conveyed materially positive clinical and IP progress: compelling Phase II efficacy with no observed recurrence among cured patients, initiation of an rCDI pilot, favorable FDA guidance that could reduce pivotal trial requirements, strengthened patent protection, supportive preclinical data, and recent financings that improved cash. Key negatives are the modest cash position relative to Phase III needs, small-scale early rCDI data requiring larger controlled trials, and remaining regulatory and design uncertainties. On balance, the positive clinical, regulatory and IP developments outweigh the operational and financing risks disclosed.Positive Updates
Strong Phase II Efficacy and No Recurrence in Cured Patients
Ibezapolstat Phase II showed a ~96% clinical cure rate and 0% recurrence among cured patients at 1 month (25/25 recurrence-free). In a subset, 5/5 patients observed out to 3 months remained recurrence-free, supporting the drug's potential to treat acute CDI and reduce recurrence.
Negative Updates
Limited Cash for Late-Stage Development
Ending cash of $9.3M, while improved, is modest relative to the capital-intensive requirements of Phase III registrational trials; management continues to pursue additional funding and initiatives to support Phase III but substantial additional capital is likely needed.
Read all updates
Q1-2026 Updates
Positive
Negative
Strong Phase II Efficacy and No Recurrence in Cured Patients
Ibezapolstat Phase II showed a ~96% clinical cure rate and 0% recurrence among cured patients at 1 month (25/25 recurrence-free). In a subset, 5/5 patients observed out to 3 months remained recurrence-free, supporting the drug's potential to treat acute CDI and reduce recurrence.
Read all positive updates
Company Guidance
The call highlighted the FDA’s new final C. difficile guidance that formalizes a default one‑trial pathway—allowing a single adequate and well‑controlled pivotal trial supported by “confirmatory” evidence (mechanistic/in‑vitro MIC and killing data, molecular mechanism, animal efficacy models, microbiome data, etc.) to meet substantial evidence of effectiveness; Acurx has an FDA meeting planned to align on this, and is initiating an open‑label rCDI pilot of 20 multiply‑recurrent patients (≥3 episodes in the prior 12 months) with a planned interim look at ~10 patients and first patient targeted around August, followed by a planned active‑controlled Phase III and potential LPAD submission for rCDI; the company will use its Phase II data as part of the confirmatory package (Phase II reported ~96% cure rate, 25/25 cured patients free of recurrence at 1 month and 5/5 free at 3 months), will follow the standard 1‑month recurrence endpoint (and extend follow‑up to 8 weeks/56 days to compare to live‑biologic comparators VOWST and REBYOTA), and reinforced program strength with IP (10 patents, including 5 U.S., with one patent extending to December 2039) and recent financing (cash $9.3M as of March 31, ~ $3.1M raised this quarter; 3,389,106 shares outstanding).Acurx Pharmaceuticals Financial Statement Overview
Summary
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Gross Profit | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| EBITDA | -7.50M | -7.97M | 0.00 | -14.58M | -12.09M | -12.75M |
| Net Income | -7.50M | -7.97M | -14.10M | -14.58M | -12.09M | -12.75M |
Balance Sheet | ||||||
| Total Assets | 9.54M | 7.69M | 3.86M | 7.71M | 9.38M | 13.25M |
| Cash, Cash Equivalents and Short-Term Investments | 9.25M | 7.56B | 3.71M | 7.47M | 9.11M | 12.96M |
| Total Debt | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Total Liabilities | 2.53M | 2.42M | 3.24M | 3.04M | 2.06M | 843.91K |
| Stockholders Equity | 7.01M | 5.27M | 615.12K | 4.67M | 7.32M | 12.41M |
Cash Flow | ||||||
| Free Cash Flow | -6.14M | -6.79B | -10.38M | -9.80M | -7.54M | -5.01M |
| Operating Cash Flow | -6.14M | -6.79B | -10.38M | -9.80M | -7.54M | -5.01M |
| Investing Cash Flow | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Financing Cash Flow | 10.75M | 10.64B | 6.62M | 8.16M | 3.70M | 14.80M |
Acurx Pharmaceuticals Technical Analysis
Neutral
1.42
Price Trends
1.56
Negative
2.20
Negative
2.81
Negative
Market Momentum
-0.03
Negative
52.97
Neutral
80.76
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ACXP, the sentiment is Neutral. The current price of 1.42 is below the 20-day moving average (MA) of 1.50, below the 50-day MA of 1.56, and below the 200-day MA of 2.81, indicating a neutral trend. The MACD of -0.03 indicates Negative momentum. The RSI at 52.97 is Neutral, neither overbought nor oversold. The STOCH value of 80.76 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for ACXP.
Acurx Pharmaceuticals Risk Analysis
Acurx Pharmaceuticals disclosed 54 risk factors in its most recent earnings report. Acurx Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Acurx Pharmaceuticals Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
54 Neutral | $15.65M | -0.22 | -67.42% | ― | ― | 55.15% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
49 Neutral | $6.19M | -0.29 | -153.93% | ― | ― | 68.70% | |
48 Neutral | $11.31M | -1.11 | -150.61% | ― | ― | 53.06% | |
44 Neutral | $26.18M | -0.49 | -139.47% | ― | 43.88% | 14.79% | |
41 Neutral | $8.14M | -0.19 | -246.04% | ― | ― | 54.48% | |
39 Underperform | $5.02M | -0.05 | -709.51% | ― | -100.00% | 77.63% |
* Healthcare Sector Average
ACXP
Acurx Pharmaceuticals
1.54
-2.94
-65.63%
SNGX
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0.39
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-83.93%
GOVX
GeoVax Labs
0.77
-16.23
-95.47%
COCP
Cocrystal Pharma
1.06
-0.54
-33.75%
CTXR
Citius Pharmaceuticals
0.68
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-45.44%
ALGS
Aligos Therapeutics
5.59
-1.98
-26.16%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.