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Sana Biotechnology (SANA)
NASDAQ:SANA
US Market
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Sana Biotechnology (SANA) AI Stock Analysis

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SANA

Sana Biotechnology

(NASDAQ:SANA)

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Neutral 53 (OpenAI - Gpt-5.6Sol)
Rating:53Neutral
Price Target:
$4.00
▼(-2.44% Downside)
Action:Reiterated
Date:09/08/26
Overall score reflects weak financial performance (no revenue, sizable losses, and ongoing cash burn with declining equity) as the main constraint. This is partly offset by improving technical momentum and a positive recent pipeline/corporate update, while valuation provides limited support due to a negative P/E and no dividend.
Positive Factors
Clinical and Pipeline Progress
Clinical validation of hypoimmune islet cells and progress toward SC451 IND readiness strengthen the credibility of Sana’s core technology. These milestones can support advancement into larger studies, broaden the addressable diabetes opportunity, and improve the company’s ability to attract partners or future funding.
Negative Factors
No Demonstrated Revenue Engine
Sana has not yet demonstrated a recurring commercial revenue stream, leaving its financial profile dependent on research progress, collaborations, and external financing. Until a therapy is commercialized or licensed, operating performance will remain disconnected from product demand and market adoption.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical and Pipeline Progress
Clinical validation of hypoimmune islet cells and progress toward SC451 IND readiness strengthen the credibility of Sana’s core technology. These milestones can support advancement into larger studies, broaden the addressable diabetes opportunity, and improve the company’s ability to attract partners or future funding.
Read all positive factors

Sana Biotechnology (SANA) vs. SPDR S&P 500 ETF (SPY)

Sana Biotechnology Business Overview & Revenue Model

Company Description
Sana Biotechnology, Inc. is a biotechnology firm focused on creating treatments using engineered cells. The company develops advanced ex vivo and in vivo cell engineering platforms to address a range of conditions with significant unmet medical ne...
How the Company Makes Money
As of the most recently available public disclosures, Sana Biotechnology has not reported a recurring product-revenue base from marketed therapies; its business model has primarily been to fund R&D through cash on hand and external financing, and ...

Sana Biotechnology Financial Statement Overview

Summary
Financial quality is weak due to essentially no revenue and large ongoing losses (TTM net loss ~-$212M) plus materially negative operating/free cash flow (TTM FCF ~-$135M). Positives include narrowing losses and improved burn versus 2023–2024, and leverage that is not excessive (debt-to-equity ~0.48), but declining equity/assets and continued cash consumption keep financing risk elevated.
Income Statement
12
Very Negative
Balance Sheet
46
Neutral
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.39M-12.75M0.000.000.000.00
EBITDA-200.99M-231.42M-249.37M-258.70M-253.85M-344.86M
Net Income-211.82M-244.17M-266.76M-283.25M-269.48M-355.93M
Balance Sheet
Total Assets431.52M416.89M501.02M565.30M822.72M1.13B
Cash, Cash Equivalents and Short-Term Investments160.49M138.38M152.50M205.19M423.96M551.00M
Total Debt73.74M78.86M94.20M104.10M108.25M110.94M
Total Liabilities276.95M256.01M250.52M277.79M323.40M400.90M
Stockholders Equity154.57M160.88M250.50M287.51M499.31M728.50M
Cash Flow
Free Cash Flow-135.06M-144.77M-256.58M-273.61M-310.93M-280.92M
Operating Cash Flow-132.24M-143.83M-223.15M-253.58M-290.05M-251.05M
Investing Cash Flow-102.60M-40.24M17.45M172.01M210.56M-245.80M
Financing Cash Flow220.64M128.73M199.75M31.65M4.91M631.75M

Sana Biotechnology Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.10
Price Trends
50DMA
3.61
Positive
100DMA
3.41
Positive
200DMA
3.70
Positive
Market Momentum
MACD
0.11
Positive
RSI
53.13
Neutral
STOCH
34.50
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SANA, the sentiment is Positive. The current price of 4.1 is above the 20-day moving average (MA) of 3.84, above the 50-day MA of 3.61, and above the 200-day MA of 3.70, indicating a bullish trend. The MACD of 0.11 indicates Positive momentum. The RSI at 53.13 is Neutral, neither overbought nor oversold. The STOCH value of 34.50 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SANA.

Sana Biotechnology Risk Analysis

Sana Biotechnology disclosed 82 risk factors in its most recent earnings report. Sana Biotechnology reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Sana Biotechnology Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$1.82B-13.25-56.19%-32.27%-21.09%
56
Neutral
$1.01B-15.75-30.31%24.39%21.06%
54
Neutral
$496.06M-4.32-196.63%20.83%73.89%
54
Neutral
$5.39B-11.72-24.39%-64.80%12.20%
53
Neutral
$1.15B-5.07-134.49%28.46%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
$671.09M-3.36-188.27%6.80%-17.90%32.10%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SANA
Sana Biotechnology
3.45
0.43
14.24%
GERN
Geron
1.51
0.15
11.03%
EDIT
Editas Medicine
3.03
0.27
9.78%
CRSP
Crispr Therapeutics AG
54.78
1.09
2.03%
TSHA
Taysha Gene Therapies
5.48
2.20
67.07%
PRME
Prime Medicine, Inc.
3.56
-0.56
-13.59%

Sana Biotechnology Corporate Events

Business Operations and StrategyRegulatory Filings and Compliance
Sana Biotechnology Highlights Progress in Diabetes and Oncology Therapies
Positive
Sep 8, 2026
On September 8, 2026, Sana Biotechnology released an updated corporate presentation for use at investor conferences, outlining recent progress in its pipeline and providing additional data on its hypoimmune cell technologies. The presentation unde...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 08, 2026