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ProKidney (PROK)
NASDAQ:PROK
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ProKidney (PROK) AI Stock Analysis

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PROK

ProKidney

(NASDAQ:PROK)

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Neutral 45 (OpenAI - Gpt-5.6Sol)
Rating:45Neutral
Price Target:
$2.00
▲(15.61% Upside)
Action:Reiterated
Date:08/11/26
The score is held down primarily by very weak financial performance (minimal revenue, large losses, and substantial cash burn implying continued financing needs). Technicals are mixed—some near-term stabilization but still below key longer-term moving averages. Corporate updates around Phase 3 progress and regulatory alignment provide a positive offset, while valuation remains unattractive on a negative P/E.
Positive Factors
Focused Cell Therapy Pipeline
A focused lead program addresses a defined chronic disease population and is designed to preserve kidney function rather than merely treat symptoms. If clinical development succeeds, this differentiated cell-therapy approach could support a durable commercial opportunity in a serious, ongoing condition.
Negative Factors
Minimal and Declining Revenue
Minimal, volatile revenue confirms that the company has not yet established a meaningful commercial revenue base. With current sales unable to support operations, the investment case remains dependent on successful clinical development, regulatory approval, and future commercialization of rilparencel.
Read all positive and negative factors
Positive Factors
Negative Factors
Focused Cell Therapy Pipeline
A focused lead program addresses a defined chronic disease population and is designed to preserve kidney function rather than merely treat symptoms. If clinical development succeeds, this differentiated cell-therapy approach could support a durable commercial opportunity in a serious, ongoing condition.
Read all positive factors

ProKidney (PROK) vs. SPDR S&P 500 ETF (SPY)

ProKidney Business Overview & Revenue Model

Company Description
ProKidney Corp. is a biotechnology firm currently in the clinical trial phase, specializing in the development of innovative cell-based treatments. Their flagship product is Renal Autologous Cell Therapy (RAC-T), a unique cellular admixture derive...
How the Company Makes Money
As a clinical-stage biotechnology company, ProKidney does not have publicly established, recurring product sales revenue from approved therapies; therefore, revenue is primarily expected to come in the future if its lead candidate (rilparencel/REA...

ProKidney Financial Statement Overview

Summary
Financial performance is very weak: minimal and volatile TTM revenue (~$0.8M) alongside very large losses (TTM net loss ~$86.7M) and heavy cash burn (TTM operating cash flow about -$141.2M; free cash flow about -$155.9M). Low reported debt (~$2.4M) helps near-term, but multi-year negative equity and continued negative free cash flow point to ongoing financing needs.
Income Statement
12
Very Negative
Balance Sheet
44
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Mar 2025Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue818.00K893.00K76.00K0.000.000.00
Gross Profit-2.07M893.00K76.00K0.000.000.00
EBITDA-160.75M-144.62M-158.49M-125.59M-143.99M-53.12M
Net Income-86.71M-68.99M-61.19M-35.47M-108.03M-55.15M
Balance Sheet
Total Assets249.02M335.57M441.07M420.55M518.00M40.30M
Cash, Cash Equivalents and Short-Term Investments181.56M270.02M358.29M362.95M490.25M20.56M
Total Debt3.52M4.04M3.24M4.41M2.40M1.33M
Total Liabilities26.18M34.78M39.44M29.22M13.06M13.38M
Stockholders Equity-883.53M-1.01B-994.95M-1.10B-1.10B26.92M
Cash Flow
Free Cash Flow-159.73M-135.31M-155.86M-124.27M-78.94M-55.49M
Operating Cash Flow-141.17M-120.12M-126.35M-90.07M-77.09M-50.30M
Investing Cash Flow104.74M103.97M20.41M-329.98M-1.74M-5.19M
Financing Cash Flow26.35M25.57M144.41M-9.55M548.52M71.47M

ProKidney Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price1.73
Price Trends
50DMA
1.67
Positive
100DMA
1.74
Positive
200DMA
1.94
Negative
Market Momentum
MACD
0.08
Negative
RSI
53.47
Neutral
STOCH
24.84
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PROK, the sentiment is Neutral. The current price of 1.73 is above the 20-day moving average (MA) of 1.72, above the 50-day MA of 1.67, and below the 200-day MA of 1.94, indicating a neutral trend. The MACD of 0.08 indicates Negative momentum. The RSI at 53.47 is Neutral, neither overbought nor oversold. The STOCH value of 24.84 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for PROK.

ProKidney Risk Analysis

ProKidney disclosed 92 risk factors in its most recent earnings report. ProKidney reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ProKidney Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$2.60B-7.28-76.09%-58.40%-31.99%
56
Neutral
$406.35M-5.15-58.82%29.97%
55
Neutral
$2.07B-21.3781.78%100.27%39.90%
53
Neutral
$4.14B-12.02-42.27%23.86%19.60%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$676.33M-6.5325.70%110.16%73.04%
45
Neutral
$544.18M-3.168.83%55.22%2.13%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PROK
ProKidney
1.80
-0.65
-26.53%
RZLT
Rezolute
4.22
-3.25
-43.51%
URGN
Urogen Pharma
42.31
24.25
134.27%
PHAT
Phathom Pharmaceuticals
8.36
-3.12
-27.18%
RLAY
Relay Therapeutics
18.87
14.81
364.78%
NRIX
Nurix Therapeutics
25.10
16.43
189.50%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 11, 2026