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Myriad Genetics (MYGN)
NASDAQ:MYGN
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Myriad Genetics (MYGN) AI Stock Analysis

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MYGN

Myriad Genetics

(NASDAQ:MYGN)

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Neutral 53 (OpenAI - Gpt-5.6Sol)
Rating:53Neutral
Price Target:
$6.50
▲(103.76% Upside)
Action:Reiterated
Date:10/21/26
The score is held back primarily by weak financial performance—persistent operating losses and still-negative/volatile free cash flow—despite strong gross margins and some recent improvement in operating cash flow. Technicals are supportive with a clear uptrend, but elevated RSI suggests near-term overheating. Corporate events are a meaningful positive (portfolio focus and $210M cash divestiture), while valuation remains constrained by ongoing losses and the absence of a dividend.
Positive Factors
Strong Gross Margins
Consistently high gross margins indicate that Myriad’s diagnostic tests generate strong economics before operating expenses. This provides a foundation for future profitability if management can control costs, improve volume, and concentrate resources on higher-value oncology and hereditary testing opportunities.
Negative Factors
Persistent Operating Losses
Strong gross margins are currently more than offset by operating expenses, leaving the company structurally unprofitable. Persistent operating and net losses weaken internal funding capacity and make the business more dependent on successful execution, cost improvement, and sustained demand for its testing portfolio.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong Gross Margins
Consistently high gross margins indicate that Myriad’s diagnostic tests generate strong economics before operating expenses. This provides a foundation for future profitability if management can control costs, improve volume, and concentrate resources on higher-value oncology and hereditary testing opportunities.
Read all positive factors

Myriad Genetics Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Shows how revenue is split across the company’s business lines—clinical genetic testing, women's health and oncology tests, and any partner or pharmaceutical-related income. Reveals which products drive growth, where pricing or reimbursement risk is concentrated, and whether Myriad is diversifying away from dependence on a single offering.
Chart InsightsThe major takeaway is the sudden emergence of Cancer Care Continuum as a material revenue line in Q1 — a structural shift that reweights the company’s mix toward new MRD/continuum products and validates commercialization progress. Hereditary cancer remains the steady growth engine with improving revenue per test, and GeneSight is a clear momentum driver via reimbursement gains. Persistent prenatal weakness and the near‑term drag from aggressive commercial hiring pressure profitability; successful MRD, Prolaris+AI and FirstGene execution will determine whether H2 acceleration materializes.
Data provided by:The Fly

Myriad Genetics (MYGN) vs. SPDR S&P 500 ETF (SPY)

Myriad Genetics Business Overview & Revenue Model

Company Description
Myriad Genetics, Inc., a molecular diagnostics and precision medicine company, develops molecular tests. The company offers molecular diagnostic tests for oncology, women’s health, and pharmacogenomics. It also provides MyRisk Hereditary Cancer te...
How the Company Makes Money
Myriad Genetics makes money primarily by performing and reporting results from proprietary genetic and molecular diagnostic tests that are ordered by healthcare providers for patients. Revenue is recognized largely on a fee-for-service basis when ...

Myriad Genetics Earnings Call Summary

Earnings Call Date:May 05, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Nov 04, 2026
Earnings Call Sentiment Positive
The call emphasized meaningful progress in core growth engines (double-digit hereditary cancer growth, robust GeneSight performance, solid gross margins and a deep product pipeline) and management reaffirmed full-year guidance and positive adjusted EBITDA expectations. Near-term pressures include a Q1 adjusted EBITDA loss, higher operating expense due to accelerated commercial hiring, and a notable prenatal revenue decline. Management is investing to drive back-half acceleration but execution (sales ramp, MRD adoption, payer reimbursement) will determine pace of recovery. On balance, the positives around market share gains, product launches and revenue guidance outweigh the short-term profitability and prenatal headwinds.
Positive Updates
Revenue within Guidance
Q1 revenue of $200.4 million, up ~2% year-over-year and within the company's Q1 guidance range; management reaffirmed full-year revenue guidance of $860M–$880M.
Negative Updates
Q1 Profitability Shortfall and Cash Burn
Reported adjusted EBITDA loss (~$4.5M–$5M) and adjusted EPS loss of $0.09 in Q1; management noted Q1 is the heaviest cash burn quarter and that accelerated commercial investments contributed to the near-term loss.
Read all updates
Q1-2026 Updates
Negative
Revenue within Guidance
Q1 revenue of $200.4 million, up ~2% year-over-year and within the company's Q1 guidance range; management reaffirmed full-year revenue guidance of $860M–$880M.
Read all positive updates
Company Guidance
Management reaffirmed full‑year 2026 guidance of $860–$880 million revenue, adjusted gross margin of 68–69% and adjusted EBITDA of $37–$49 million, while expecting sequential revenue growth in the low single digits in Q2 that accelerates through the back half (H2 stronger than H1). Q1 results were revenue $200.4M (within guidance) with 385k test results, gross margin ~68.7–69%, an adjusted EBITDA loss of roughly $4.5–$5.0M and adjusted EPS loss of $0.09; average revenue per test improved ~2% YoY. Operational highlights underpinning the guide included Cancer Care Continuum revenue of $120.2M (+4% YoY) with hereditary testing volume +14% YoY (affected +10%, unaffected +16%), GeneSight revenue $38.3M (+24% YoY) on +7% volume and >39,000 ordering clinicians, prenatal revenue $41.9M (‑15% YoY) and Prolaris mid‑single‑digit growth. Management also cited $199M in available capital, a planned $35M investment in commercial capabilities, hiring of over 100 account executives, and timing for key launches (Prolaris+AI in June, FirstGene commercial in H2’26, broader Precise MRD expansion in Q3 and full MRD commercialization in Q1’27).

Myriad Genetics Financial Statement Overview

Summary
Strong gross margins (~69–71%) support product-level economics, but the business remains structurally unprofitable with very negative operating results (TTM operating margin ~-46%) and persistent net losses. Cash flow is improving (TTM operating cash flow slightly positive), yet free cash flow remains slightly negative and has been volatile; leverage has risen versus prior years, increasing execution risk until profitability improves.
Income Statement
28
Negative
Balance Sheet
54
Neutral
Cash Flow
32
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue806.60M824.50M837.60M753.20M678.40M690.60M
Gross Profit555.20M576.60M585.40M517.00M476.40M493.00M
EBITDA-45.20M-330.90M-59.50M-197.40M-84.70M12.30M
Net Income-112.60M-365.90M-127.30M-263.30M-112.00M-27.20M
Balance Sheet
Total Assets638.90M706.60M1.03B1.15B1.20B1.32B
Cash, Cash Equivalents and Short-Term Investments115.20M149.60M102.40M140.90M114.90M338.80M
Total Debt210.50M209.80M140.30M152.10M145.00M92.30M
Total Liabilities335.00M338.60M326.50M363.30M312.90M352.90M
Stockholders Equity303.90M368.00M701.10M783.20M885.80M967.80M
Cash Flow
Free Cash Flow-8.60M-25.60M-38.40M-184.20M-151.60M600.00K
Operating Cash Flow7.70M1.80M-8.70M-110.90M-106.30M18.60M
Investing Cash Flow-21.90M-27.40M-11.90M31.90M-77.50M274.40M
Financing Cash Flow47.20M64.20M-7.40M152.90M-8.00M-150.60M

Myriad Genetics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price3.19
Price Trends
50DMA
4.01
Positive
100DMA
4.42
Positive
200DMA
4.60
Positive
Market Momentum
MACD
0.53
Negative
RSI
78.69
Negative
STOCH
96.35
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MYGN, the sentiment is Positive. The current price of 3.19 is below the 20-day moving average (MA) of 4.73, below the 50-day MA of 4.01, and below the 200-day MA of 4.60, indicating a bullish trend. The MACD of 0.53 indicates Negative momentum. The RSI at 78.69 is Negative, neither overbought nor oversold. The STOCH value of 96.35 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MYGN.

Myriad Genetics Risk Analysis

Myriad Genetics disclosed 52 risk factors in its most recent earnings report. Myriad Genetics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Myriad Genetics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$4.04B34.928.64%―17.28%323.64%
71
Outperform
$1.05B-52.33-4.15%―3.18%-100.37%
67
Neutral
$59.22B-302.07-11.73%―37.82%28.02%
53
Neutral
$601.64M-5.26-32.59%13.45%-3.16%72.02%
52
Neutral
$1.87B-17.24-38.72%―25.42%-10900.00%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$569.57M-7.34-7.87%―6.83%-69.59%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MYGN
Myriad Genetics
6.29
-1.62
-20.48%
VCYT
Veracyte
50.28
14.87
41.99%
NTRA
Natera
410.82
218.01
113.07%
FLGT
Fulgent Genetics
20.70
-2.03
-8.93%
CSTL
Castle Biosciences
34.51
10.77
45.37%
WGS
GeneDx Holdings
62.74
-69.02
-52.38%

Myriad Genetics Corporate Events

Business Operations and StrategyM&A Transactions
Myriad Genetics to Divest Prenatal Testing Business
Positive
Oct 20, 2026
On October 19–20, 2026, Myriad Genetics and Labcorp announced a definitive agreement under which Myriad will sell its Prenatal Health testing business, including the Prequel, Foresight, SneakPeek and FirstGene tests, to Labcorp for $210 mill...
Executive/Board ChangesRegulatory Filings and Compliance
Myriad Genetics Finalizes Separation Agreement With Former CCO
Neutral
Oct 9, 2026
Myriad Genetics, Inc. disclosed that former Chief Commercial Officer Brian Donnelly departed his role effective September 16, 2026, with his employment ending on September 21, 2026. On October 6, 2026, the company entered into a Separation Agreeme...
Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
Myriad Genetics Announces Key Commercial Leadership Transition
Positive
Sep 16, 2026
On September 16, 2026, Myriad Genetics announced a leadership transition in its commercial organization, promoting Senior Vice President of Product Vishal Sikri to Executive Vice President, Commercial. Sikri brings deep experience in molecular dia...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 21, 2026