tiprankstipranks
Trending News
More News >
ACADIA Pharmaceuticals (ACAD)
NASDAQ:ACAD
Advertisement

ACADIA Pharmaceuticals (ACAD) AI Stock Analysis

Compare
2,398 Followers

Top Page

ACAD

ACADIA Pharmaceuticals

(NASDAQ:ACAD)

Select Model
Select Model
Select Model
Neutral 68 (OpenAI - 4o)
Rating:68Neutral
Price Target:
$23.00
▲(8.29% Upside)
ACADIA Pharmaceuticals' strong financial performance and positive earnings call sentiment are the most significant factors driving the stock score. The company has demonstrated consistent revenue growth and efficient cost management. However, technical analysis indicates bearish momentum, which slightly offsets the positive financial outlook. The valuation is fair, but the lack of a dividend yield is a minor drawback.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong market demand and effective sales strategies, supporting long-term financial stability and expansion.
Pipeline Expansion
A robust pipeline with multiple late-stage trials enhances future growth prospects, diversifies revenue streams, and strengthens competitive position.
Cash Flow Generation
Strong cash flow generation supports operational flexibility, investment in R&D, and potential strategic acquisitions, underpinning long-term growth.
Negative Factors
Increased SG&A Expenses
Rising SG&A expenses can pressure margins and profitability, potentially limiting resources available for R&D and other growth initiatives.
Challenges in Clinical Trials
Clinical trial challenges can delay product development and approval timelines, impacting future revenue streams and competitive positioning.
Net Profit Margin Pressure
Decreasing net profit margins may indicate cost pressures or pricing challenges, potentially affecting long-term profitability and shareholder returns.

ACADIA Pharmaceuticals (ACAD) vs. SPDR S&P 500 ETF (SPY)

ACADIA Pharmaceuticals Business Overview & Revenue Model

Company DescriptionACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of small molecule drugs that address unmet medical needs in central nervous system disorders. The company offers NUPLAZID (pimavanserin) for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis. It's pipeline include, pimavanserin, under phase 3 development for the treatment of Alzheimer's disease psychosis, and negative symptoms of schizophrenia; Trofinetide, a novel synthetic analog, under phase 3 development for the treatment of Rett syndrome; ACP-044, a novel first-in-class orally administered non-opioid analgesic, under phase 2 development for treating acute and chronic pain; and ACP-319, a positive allosteric modulator of the muscarinic receptor, under phase 1 development for treating schizophrenia and cognition in Alzheimer's. ACADIA Pharmaceuticals Inc. was founded in 1993 and is headquartered in San Diego, California.
How the Company Makes MoneyACADIA Pharmaceuticals generates revenue primarily through the sale of its flagship product, NUPLAZID. The company earns income from product sales to healthcare providers and pharmacies. Additionally, ACADIA may receive milestone payments and royalties from partnerships with other pharmaceutical companies involved in the development and commercialization of complementary therapies. The company also engages in research collaborations and licensing agreements that can provide additional revenue streams. Factors contributing to its earnings include the growth in demand for treatments for CNS disorders, successful marketing strategies, and potential new product approvals or expansions in indications for existing drugs.

ACADIA Pharmaceuticals Key Performance Indicators (KPIs)

Any
Any
Revenue by Product
Revenue by Product
Shows earnings from individual products, highlighting which offerings drive growth and which may need strategic adjustments. This helps assess product portfolio strength and market positioning.
Chart InsightsACADIA Pharmaceuticals is experiencing robust growth in its key products, with NUPLAZID and DAYBUE showing significant revenue increases. NUPLAZID's revenue surged by 23% due to a one-time adjustment, while DAYBUE's sales rose by 11%, despite a sequential decline attributed to seasonality and prior quarter pull-forward. The company is strategically expanding its pipeline and preparing for DAYBUE's European launch, indicating strong future prospects. However, increased R&D expenses and the discontinuation of certain programs highlight ongoing challenges in balancing growth and operational costs.
Data provided by:Main Street Data

ACADIA Pharmaceuticals Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 11, 2025
Earnings Call Sentiment Positive
The earnings call reflected a positive sentiment overall, with strong financial performance, significant growth in DAYBUE and NUPLAZID sales, and a robust pipeline expansion. However, increased SG&A expenses and challenges in clinical trials were noted as areas of concern.
Q2-2025 Updates
Positive Updates
Strong Financial Performance
ACADIA achieved total revenue of $264.6 million for the quarter, marking a 9% year-over-year increase.
DAYBUE Growth
DAYBUE net product sales reached $96.1 million, up 14% from the previous year, with a steady increase in patient uptake.
NUPLAZID Performance
NUPLAZID sales were $168.5 million, a 7% year-over-year increase, driven by a 17% rise in referrals and successful direct-to-consumer campaigns.
Pipeline Expansion
9 disclosed programs in development with 5 Phase II or III data readouts expected through 2027. Notable programs include ACP-211 for major depressive disorder and ACP-271 for tardive dyskinesia and Huntington's disease.
Increased Cash Balance
Cash balance increased to $762 million, from $756 million at the end of 2024.
Negative Updates
Increased SG&A Expenses
SG&A expenses rose to $133.5 million from $117.1 million in the prior year, attributed to increased expenditures for DAYBUE and NUPLAZID in the U.S.
Challenges in Clinical Trials
Ongoing challenges in conducting clinical trials, including the need for consistent behavior across sites in the Phase III Prader-Willi syndrome study.
Company Guidance
During the ACADIA Pharmaceuticals second quarter 2025 conference call, the company reported robust financial performance and growth across its portfolio. Total revenue for the quarter was $264.6 million, a 9% increase year-over-year, driven by sales of DAYBUE and NUPLAZID, which contributed $96.1 million and $168.5 million respectively. DAYBUE sales were up by 14% from the previous year, with a 12-month persistency rate exceeding 50% and an 18-month rate over 45%. NUPLAZID's revenue grew by 7% year-over-year, supported by a successful direct-to-consumer campaign, resulting in a 17% increase in referrals. The company raised the lower end of its NUPLAZID sales guidance to $665 million - $690 million for 2025, reflecting strong performance. R&D expenses for the quarter were $78 million, while SG&A expenses were $133.5 million. ACADIA ended the quarter with a cash balance of $762 million. The company also highlighted its expanding pipeline, with expectations for several Phase II and III studies in the coming years.

ACADIA Pharmaceuticals Financial Statement Overview

Summary
ACADIA Pharmaceuticals shows strong financial health with consistent revenue growth, improved profitability, and positive cash flows. The balance sheet reflects stability with minimal leverage, and the overall financial performance indicates a positive outlook. Continued focus on maintaining profitability and managing debt levels will be crucial for sustaining this momentum.
Income Statement
75
Positive
The company has shown impressive revenue growth with a TTM (Trailing-Twelve-Months) revenue of $996.3 million, up from $957.8 million in the previous year, indicating a strong upward trajectory. The gross profit margin remains robust at approximately 92.0%, reflecting efficient cost management. Net profit margin has improved significantly, turning positive, which highlights enhanced profitability. EBIT and EBITDA margins are also positive, further emphasizing operational improvements.
Balance Sheet
80
Positive
ACADIA Pharmaceuticals demonstrates a healthy balance sheet with a low debt-to-equity ratio, suggesting prudent financial management. The equity ratio is high, indicating a strong reliance on equity financing. Return on Equity (ROE) is positive and improving, showcasing the company's ability to generate returns on shareholders' investments. However, the company's debt levels, while manageable, should be monitored as they have increased slightly.
Cash Flow
70
Positive
The company has achieved positive free cash flow, marking a significant improvement from previous years. Operating cash flow to net income ratio is healthy, suggesting effective cash management. While the free cash flow growth rate has declined slightly in the latest TTM period compared to the previous year, the overall cash flow position is solid, supporting future growth initiatives.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.02B957.80M726.44M517.24M484.14M441.75M
Gross Profit937.10M875.96M680.71M507.07M465.00M421.20M
EBITDA106.30M100.16M-67.83M-221.57M-167.09M-286.59M
Net Income222.16M226.45M-61.29M-215.97M-167.87M-281.58M
Balance Sheet
Total Assets1.23B1.19B748.96M587.81M700.12M782.62M
Cash, Cash Equivalents and Short-Term Investments762.00M755.99M438.87M416.82M520.71M631.96M
Total Debt44.60M51.99M57.20M62.00M56.13M44.46M
Total Liabilities403.17M454.96M317.20M187.40M159.23M155.61M
Stockholders Equity822.38M732.79M431.75M400.41M540.89M627.01M
Cash Flow
Free Cash Flow187.09M157.20M-23.35M-114.03M-126.78M-143.75M
Operating Cash Flow187.91M157.72M16.70M-114.03M-125.66M-136.17M
Investing Cash Flow-127.65M-30.54M32.00M73.24M-71.10M192.51M
Financing Cash Flow20.03M6.84M25.13M8.20M18.16M81.00M

ACADIA Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price21.24
Price Trends
50DMA
24.19
Negative
100DMA
22.79
Negative
200DMA
19.99
Positive
Market Momentum
MACD
-0.87
Positive
RSI
32.58
Neutral
STOCH
25.02
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ACAD, the sentiment is Negative. The current price of 21.24 is below the 20-day moving average (MA) of 23.73, below the 50-day MA of 24.19, and above the 200-day MA of 19.99, indicating a neutral trend. The MACD of -0.87 indicates Positive momentum. The RSI at 32.58 is Neutral, neither overbought nor oversold. The STOCH value of 25.02 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ACAD.

ACADIA Pharmaceuticals Risk Analysis

ACADIA Pharmaceuticals disclosed 55 risk factors in its most recent earnings report. ACADIA Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ACADIA Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$5.12B35.9114.10%116.09%35.29%
68
Neutral
$3.60B16.0433.18%14.41%627.78%
58
Neutral
$4.82B8.80-304.62%96.00%
57
Neutral
$4.67B-27.30-323.27%2816.21%73.33%
51
Neutral
$4.39B-24.05-23.60%-60.63%-216.87%
41
Neutral
$401.12M-2.57-208.46%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ACAD
ACADIA Pharmaceuticals
21.34
6.21
41.04%
ARWR
Arrowhead Pharmaceuticals
35.01
15.79
82.15%
PTCT
PTC Therapeutics
61.37
24.94
68.46%
KRYS
Krystal Biotech
179.61
2.23
1.26%
MLTX
MoonLake Immunotherapeutics
7.17
-44.65
-86.16%
ACLX
Arcellx Inc
82.03
5.80
7.61%

ACADIA Pharmaceuticals Corporate Events

Legal Proceedings
Acadia Pharmaceuticals Wins Patent Case for NUPLAZID
Positive
Jun 10, 2025

On June 9, 2025, Acadia Pharmaceuticals announced that the U.S. Court of Appeals for the Federal Circuit upheld a previous decision by the U.S. District Court for the District of Delaware, confirming the validity of the company’s composition of matter patent for NUPLAZID® (pimavanserin). This legal victory against MSN Laboratories and its affiliate MSN Pharmaceuticals reinforces Acadia’s patent position, potentially strengthening its market position and providing assurance to stakeholders regarding the protection of its intellectual property.

The most recent analyst rating on (ACAD) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on ACADIA Pharmaceuticals stock, see the ACAD Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Acadia Pharmaceuticals Holds 2025 Annual Stockholder Meeting
Neutral
May 29, 2025

On May 29, 2025, Acadia Pharmaceuticals Inc. held its 2025 Annual Meeting of Stockholders, where three Class III directors were elected to the Board of Directors to serve until the 2028 Annual Meeting. Additionally, stockholders approved the compensation of the company’s named executive officers and ratified the appointment of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025.

The most recent analyst rating on (ACAD) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on ACADIA Pharmaceuticals stock, see the ACAD Stock Forecast page.

Legal ProceedingsBusiness Operations and Strategy
ACADIA Pharmaceuticals Wins Favorable Patent Court Ruling
Positive
May 20, 2025

On May 15, 2025, ACADIA Pharmaceuticals entered into a 12-year lease agreement for new executive office space at 210 Carnegie Center in Princeton, New Jersey, with plans for commercial, research, and development activities. The company will pay an initial annual rent of $1,899,756, with incremental increases, and is responsible for operating expenses and property taxes. Additionally, ACADIA announced a favorable court ruling on May 16, 2025, regarding its formulation patent for NUPLAZID®, securing its position against competitors Aurobindo Pharma and MSN Laboratories.

The most recent analyst rating on (ACAD) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on ACADIA Pharmaceuticals stock, see the ACAD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 25, 2025