Revolution Medicines, Inc. ((RVMD)) announced an update on their ongoing clinical study.
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Revolution Medicines, Inc. is conducting a Phase 1b clinical study titled ‘Phase 1b, Multicenter, Open-Label, Dose Escalation and Dose Expansion Study of RMC-6291 in Combination with RMC-6236 in Participants with Advanced KRAS G12C Mutant Solid Tumors.’ The study aims to evaluate the safety, tolerability, and pharmacokinetic profiles of the drug combination RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors, including non-small cell lung cancer, colorectal cancer, and pancreatic ductal adenocarcinoma.
The intervention involves the experimental use of oral tablets RMC-6291 and RMC-6236, designed to target and treat advanced KRAS G12C mutant solid tumors. The primary purpose is treatment, with a focus on dose escalation and expansion to assess the drugs’ effects.
This interventional study uses a single-group assignment model without masking, meaning all participants receive the treatment and are aware of it. The open-label design facilitates a straightforward assessment of the treatment’s impact.
The study began recruiting on November 7, 2023, with its last update submitted on March 24, 2025. These dates are crucial as they mark the study’s progression and the latest developments available for investor evaluation.
For investors, this study represents a significant step for Revolution Medicines in the competitive oncology market. Positive outcomes could enhance the company’s stock performance and investor confidence, especially given the high interest in KRAS-targeted therapies. The ongoing recruitment and study updates suggest continued momentum and potential future announcements that could influence market dynamics.
The study is ongoing, with further details accessible on the ClinicalTrials portal.