Pliant Therapeutics, Inc. ( (PLRX) ) has released its Q3 earnings. Here is a breakdown of the information Pliant Therapeutics, Inc. presented to its investors.
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Pliant Therapeutics, Inc. is a clinical-stage biotechnology company specializing in the development of integrin-based therapeutics, primarily targeting solid tumors and muscular dystrophies. In its latest financial report, Pliant Therapeutics highlighted significant advancements in its oncology program and financial performance for the third quarter of 2025. The company completed enrollment in a Phase 1 trial for its lead drug candidate, PLN-101095, and expects to release data by the end of the year.
The company’s financial results for the third quarter showed a marked improvement, with research and development expenses dropping to $17.9 million from $47.8 million in the previous year, largely due to the discontinuation of the BEACON-IPF trial. General and administrative expenses also decreased to $10.3 million, contributing to a reduced net loss of $26.3 million compared to $57.8 million in the same period last year.
Pliant Therapeutics’ strategic restructuring and cost-saving measures have resulted in a healthier financial position, with cash, cash equivalents, and short-term investments totaling $243.3 million as of September 30, 2025. The company also completed a voluntary prepayment of its outstanding loan with Oxford Finance LLC, further strengthening its financial standing.
Looking ahead, Pliant Therapeutics remains focused on advancing its clinical programs and exploring opportunities to enhance shareholder value. The company is poised to complete the close-out activities for the BEACON-IPF trial and anticipates further developments in its oncology pipeline, positioning itself for potential growth in the biotechnology sector.

