Charles River Laboratories Intl ((CRL)) has held its Q3 earnings call. Read on for the main highlights of the call.
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The recent earnings call of Charles River Laboratories Intl presented a mixed sentiment. While there were positive developments such as improvements in biotech funding, strategic portfolio adjustments, and growth in the RMS segment, these were counterbalanced by declines in revenue in key segments, a decrease in operating margins, and a drop in earnings per share.
Strategic Review and Portfolio Strengthening
The strategic review undertaken by Charles River Laboratories has led to a focus on strengthening core markets, divesting underperforming assets, and authorizing a new $1 billion stock repurchase. The board supports this strategic direction, aiming to increase non-GAAP earnings by at least $0.30 per share through these divestitures by mid-2026.
Improvement in Biotech Funding Environment
Biotech funding showed significant improvement in the third quarter, with October marking the second-highest month in biotech history. This improvement indicates an upward trend in potential client demand, suggesting a positive outlook for future engagements.
RMS Segment Performance
The RMS segment experienced a 6.5% increase in revenue on an organic basis compared to the third quarter of 2024. This growth was primarily driven by favorable timing of non-human primate (NHP) shipments, highlighting the segment’s robust performance.
DSA Proposal Activity and Bookings
There was an improvement in proposal activity, particularly for biotech clients, with high single-digit increases both year-over-year and sequentially. This suggests a growing interest and engagement from biotech clients, which could bode well for future revenue streams.
Free Cash Flow Improvement
The company reported an $8.9 million sequential improvement in free cash flow, reflecting disciplined capital spending and effective working capital management. This improvement underscores the company’s focus on maintaining financial health.
NAMs Capabilities Development
Charles River is developing its NAMs capabilities, including next-generation sequencing solutions and animal-free products. This development indicates a forward-looking approach in innovation, positioning the company for future growth in these areas.
Revenue Decline
The third quarter revenue was reported at $1 billion, marking a 0.5% decrease year-over-year, with an organic decline of 1.6% due to declines in the DSA and Manufacturing segments. This decline highlights the challenges faced in maintaining revenue growth.
DSA Segment Revenue Decrease
The DSA segment saw a 3.1% decrease in revenue year-over-year on an organic basis, driven by lower revenue for both Discovery and Safety Assessment Services. This decline points to challenges within these specific services.
Manufacturing Segment Challenges
Manufacturing revenue decreased by 5.1% on an organic basis, largely due to lower commercial revenue from CDMO clients. This decrease underscores the challenges faced in the manufacturing segment.
Operating Margin Decline
The operating margin was reported at 19.7%, a decrease of 20 basis points year-over-year. This decline was mainly due to lower sales volume in the DSA and Manufacturing segments, reflecting the impact of reduced demand.
Earnings Per Share Decline
Earnings per share were $2.43, a 6.2% decline from the third quarter of last year, affected by new tax legislation. This decline in earnings per share highlights the financial pressures faced by the company.
Forward-Looking Guidance
Charles River Laboratories provided updated guidance, anticipating a 1.5% to 2.5% organic revenue decline for 2025, with non-GAAP earnings per share expected at the higher end of the previous range, between $10.10 and $10.30. The strategic review has led to plans for divesting approximately 7% of revenue-generating underperforming or non-core assets, expected to contribute at least $0.30 per share in non-GAAP earnings accretion annually. The company also aims for $225 million in cumulative annualized cost savings by 2026, alongside an additional $70 million in savings from new efficiency initiatives. The Board has approved a new $1 billion stock repurchase authorization. Despite the challenges, the company remains optimistic about improving trends in demand and proposals, especially from biotech clients.
In summary, the earnings call of Charles River Laboratories Intl reflected a mixed sentiment, with positive developments in biotech funding and strategic adjustments countered by declines in revenue and earnings. The company is taking strategic steps to strengthen its portfolio and improve financial health, with a cautious yet optimistic outlook for the future.

