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Centessa Pharmaceuticals Advances OX2R Agonist Program

Centessa Pharmaceuticals Advances OX2R Agonist Program

Centessa Pharmaceuticals Plc ( (CNTA) ) has released its Q3 earnings. Here is a breakdown of the information Centessa Pharmaceuticals Plc presented to its investors.

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Centessa Pharmaceuticals Plc is a clinical-stage pharmaceutical company focused on developing innovative treatments for neurological and neuropsychiatric disorders, particularly through its OX2R agonist program. In its latest earnings report, Centessa Pharmaceuticals highlighted significant progress in its OX2R agonist program, including promising Phase 2a data for ORX750, which shows potential as a best-in-class treatment for narcolepsy and idiopathic hypersomnia. The company also reported advancements in its other drug candidates, ORX142 and ORX489, with plans to initiate further clinical studies in early 2026. Financially, Centessa reported a net loss of $54.9 million for the third quarter of 2025, with increased R&D expenses reflecting its ongoing commitment to drug development. Despite the losses, the company maintains a strong cash position, expected to fund operations into mid-2027. Looking ahead, Centessa Pharmaceuticals is poised to continue its leadership in the OX2R agonist space, with multiple clinical milestones anticipated in the coming year.

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