Virgin Galactic Holdings, Affimed N.V., and Amesite Inc. are the 3 Penny Stocks to watch on May 20, 2025, based on TipRanks’ Penny Stock Screener tool. Penny stocks are defined as stocks that trade at or below $5 per share and have a market capitalization of below $300 million.
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The Penny Stock Screener helps investors scan stocks based on numerous parameters, including Sector, Price Target Upside, Smart Score, Analyst Consensus, Dollar Volume, and Price Change.
We leveraged the tool to pick the top three penny stocks with the highest Dollar Volume as of the close on May 19, 2025. Simply put, Dollar Volume is the number of shares traded on a particular day multiplied by the day’s share price.

Virgin Galactic Holdings (SPCE) – Richard Branson-founded Virgin Galactic is an aerospace and space travel company, with a mission of sending individuals and researchers to space. On May 19, SPCE had a Dollar Volume of $526.47 million, while its stock price fell by 9.8%.
The share price decline seems to be a reversal from Friday’s rally of 43.3%. Virgin Galactic reported better-than-expected sales for Q1FY25 on Thursday, May 15. At the same time, the company confirmed that ticket sales are slated to reopen in Q1 2026, and the first commercial flight using its upgraded Delta fleet is planned for fall 2026. This positive outlook prompted heavy trading in SPCE stock over the past few days.
Affimed N.V. (AFMD) – Affimed is a clinical-stage biopharmaceutical company, focused on developing novel treatments for cancer. On Monday, AFMD had a Dollar Volume of $256.48 million, accompanied by a stock price plunge of nearly 35%.
There was no specific news for Affimed yesterday, but its shares surged over 228% on Friday. On May 14, the company announced that it had received a written delisting notice from the Nasdaq Listing Qualifications Department, notifying it that the trading of the company’s common shares will be suspended at the opening of business on May 20, 2025. Shares have been reacting to this news.
Amesite Inc. (AMST) – Amesite is an artificial intelligence (AI) platform that develops B2C (business-to-consumer) and B2B (business-to-business) apps, focused on home and healthcare segments. AMST had a Dollar Volume of $217.98 million on Monday, while its stock price declined by 9.8%.
The recent decline in Amesite’s stock price seems to be a correction from Friday’s 50% jump. The company announced solid results for Q3FY25, with accelerated growth in both B2C and B2B segments. Amesite’s flagship app, NurseMagic, reported a 2.4x sequential revenue increase in Q3. At the same time, Amesite is actively cutting down expenses to improve operational efficiencies and manage margins.
To find more penny stocks like these, you can take a look at TipRanks’ Penny Stock Screener tool. It shows a list of all penny stocks, their price movement, and other vital data.