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OZEM - ETF AI Analysis

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OZEM

Roundhill GLP-1 & Weight Loss ETF (OZEM)

Rating:55Neutral
Price Target:
OZEM, the Roundhill GLP-1 & Weight Loss ETF, earns a solid overall rating driven mainly by its large positions in established drug makers like Novo Nordisk, Eli Lilly, Pfizer, and Amgen, which combine strong financial performance with attractive long-term growth prospects. However, exposure to earlier-stage biotech such as Viking Therapeutics, with high losses and valuation concerns, slightly weighs on the fund’s quality, and the heavy concentration in the weight-loss and GLP-1 pharmaceutical theme is the key risk if sentiment or regulation turns against this sector.
Positive Factors
Focused Exposure to Weight-Loss Theme
The ETF targets companies involved in GLP-1 and weight-loss treatments, giving investors direct exposure to a fast-growing area of health care.
Strong Performance From Key Holdings
Several major positions like Eli Lilly, Viking Therapeutics, CSPC Pharmaceutical Group, and Amgen have shown strong gains, helping support the fund’s recent results.
Global Health Care Diversification
Holdings spread across the U.S., Hong Kong, and Japan within health care reduce reliance on any single country’s regulatory or market environment.
Negative Factors
High Sector Concentration in Health Care
With most assets in health care, the fund is heavily exposed to industry-specific risks such as drug trial setbacks and regulatory changes.
Notable Underperforming Holdings
Some sizable positions like Kailera Therapeutics, Chugai Pharmaceutical, and Ascletis Pharma have shown weak performance, which can drag on overall returns.
Above-Average Expense Ratio
The fund’s relatively high fee means more of the returns go to costs, which can be a bigger concern if performance remains weak over time.

OZEM vs. SPDR S&P 500 ETF (SPY)

OZEM Summary

Roundhill GLP-1 & Weight Loss ETF (OZEM) focuses on companies working on weight-loss drugs and treatments, especially GLP-1 medicines used for obesity and related health issues. It doesn’t track a traditional index, but instead targets a specific theme in healthcare and biotech. The fund holds major drug makers like Novo Nordisk and Eli Lilly, along with smaller biotech firms, giving investors a mix of established names and potential up-and-comers. Someone might invest for long-term growth tied to rising demand for weight-loss treatments. A key risk is that it’s heavily concentrated in healthcare and can swing sharply with drug trial results, regulation, and market sentiment.
How much will it cost me?The Roundhill GLP-1 & Weight Loss ETF (OZEM) has an expense ratio of 0.59%, meaning you’ll pay $5.90 per year for every $1,000 invested. This is higher than average because it is actively managed, focusing on a niche sector like pharmaceuticals and biotechnology, which requires more research and specialized management.
What would affect this ETF?The Roundhill GLP-1 & Weight Loss ETF could benefit from growing global demand for innovative health solutions, particularly in obesity and metabolic disorder treatments, as well as advancements in biotechnology and pharmaceuticals led by top holdings like Novo Nordisk and Eli Lilly. However, potential risks include regulatory hurdles, competition in the weight management sector, and broader economic challenges that may impact healthcare spending or innovation funding. Global exposure also means the ETF could be affected by geopolitical events or currency fluctuations.

OZEM Top 10 Holdings

OZEM is tightly hitched to the GLP-1 and obesity-treatment story, with heavyweights Novo Nordisk and Eli Lilly setting the tone. Both have been a bit choppy lately, so they’re no longer pulling the fund quite as strongly as before. Instead, steadier names like Pfizer and a rising Amgen are doing more of the heavy lifting. On the flip side, smaller biotech players such as Kailera look more like dead weight for now. While the theme is narrow, the fund spreads its bets globally across U.S., European, and Asian drugmakers.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Eli Lilly & Co12.65%$7.28M$1.07T51.05%
72
Outperform
Novo Nordisk11.86%$6.83M$185.59B-30.17%
73
Outperform
Pfizer7.65%$4.41M$156.51B14.45%
74
Outperform
CSPC Pharmaceutical Group7.05%$4.06MHK$101.29B-9.41%
63
Neutral
5.25%$3.02M
Viking Therapeutics4.66%$2.68M$3.44B12.75%
53
Neutral
Chugai Pharmaceutical Co4.24%$2.44M¥10.61T-9.06%
74
Outperform
Amgen4.20%$2.42M$203.47B33.06%
77
Outperform
3.92%$2.26M
Kailera Therapeutics, Inc.3.77%$2.17M$1.65B

OZEM Technical Analysis

Technical Analysis Sentiment
Negative
Last Price
Price Trends
50DMA
32.73
Negative
100DMA
32.03
Negative
200DMA
32.75
Negative
Market Momentum
MACD
-0.56
Positive
RSI
38.78
Neutral
STOCH
19.75
Positive
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For OZEM, the sentiment is Negative. The current price of undefined is equal to the 20-day moving average (MA) of 32.61, equal to the 50-day MA of 32.73, and equal to the 200-day MA of 32.75, indicating a bearish trend. The MACD of -0.56 indicates Positive momentum. The RSI at 38.78 is Neutral, neither overbought nor oversold. The STOCH value of 19.75 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OZEM.

OZEM Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$58.42M0.59%
55
Neutral
$56.55M1.00%
44
Neutral
$53.86M0.75%
66
Neutral
$50.77M0.50%
58
Neutral
$43.11M0.80%
63
Neutral
$32.20M0.44%
63
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OZEM
Roundhill GLP-1 & Weight Loss ETF
31.30
4.73
17.80%
PSIL
AdvisorShares Psychedelics ETF
HRTS
Tema Cardiovascular and Metabolic ETF
FMED
Fidelity Disruptive Medicine ETF
MEDI
Harbor Health Care ETF
TMED
T. Rowe Price Health Care ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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