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LFSC - ETF AI Analysis

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LFSC

F/M Emerald Life Sciences Innovation ETF (LFSC)

Rating:51Neutral
Price Target:
LFSC, the F/M Emerald Life Sciences Innovation ETF, has a mixed overall rating that reflects both promising growth stories and meaningful risks in its portfolio of life sciences companies. Stronger holdings like Corcept Therapeutics, which shows solid financial health and positive technical trends, and LivaNova, with robust revenue growth and improving metrics, help support the fund’s quality. However, weaker positions such as Cogent Biosciences and Spyre Therapeutics, both facing serious financial and profitability challenges, along with the fund’s concentration in high-risk biotech and life sciences names, weigh on the rating and increase overall risk.
Positive Factors
Strong Recent Performance
The ETF has delivered strong gains so far this year and in recent months, showing solid momentum.
Top Holdings Showing Strong Gains
Several of the largest positions, such as Spyre Therapeutics and Corcept Therapeutics, have posted strong advances, helping drive the fund’s returns.
Focused Exposure to Health Care Innovation
With most assets in health care and life sciences companies, the fund offers targeted exposure to a sector that can benefit from medical and biotech innovation.
Negative Factors
High Sector Concentration
The ETF is heavily concentrated in health care, so a downturn in this single sector could significantly hurt performance.
Limited Geographic Diversification
Almost all holdings are in U.S. companies, which reduces the benefits of global diversification and ties results closely to the U.S. market.
Above-Average Expense Ratio
The fund’s expense ratio is relatively high for an ETF, which means more of the returns are used to cover fees instead of going to investors.

LFSC vs. SPDR S&P 500 ETF (SPY)

LFSC Summary

LFSC is the F/M Emerald Life Sciences Innovation ETF, focused on innovative health care companies in pharma, biotech, and life sciences rather than tracking a traditional index. It mainly holds U.S. firms working on new drugs, medical tests, and treatments, including names like Guardant Health and United Therapeutics. Investors might consider LFSC if they want growth potential from cutting-edge medical breakthroughs and added diversification within the health care sector. However, this ETF is heavily concentrated in smaller, specialized biotech and pharma stocks, so its price can be very volatile and may go up and down sharply.
How much will it cost me?The F/M Emerald Life Sciences Innovation ETF (LFSC) has an expense ratio of 0.54%, meaning you’ll pay $5.40 per year for every $1,000 invested. This is slightly higher than average because it’s actively managed, focusing on specialized companies in the Pharma, Biotech & Life Sciences sector to capture unique growth opportunities.
What would affect this ETF?The LFSC ETF, focused on U.S.-based pharmaceutical, biotech, and life sciences companies, could benefit from advancements in medical technology, increased healthcare spending, and favorable regulatory approvals for new treatments. However, it may face challenges from rising interest rates, which can impact funding for innovation, and regulatory hurdles that could delay drug approvals or increase costs for its top holdings. Economic downturns or reduced government healthcare budgets could also negatively affect the sector.

LFSC Top 10 Holdings

LFSC is a pure play on U.S. life sciences, with performance largely riding on a handful of high‑beta biotech names. Spyre Therapeutics and Corcept Therapeutics have been rising sharply, acting as the fund’s main engines, while Travere Therapeutics and LivaNova show more mixed, stop‑and‑go momentum. Guardant Health adds another growth‑oriented, but financially shaky, leg to the story, keeping volatility high. Overall, this ETF is heavily concentrated in innovative, often unprofitable health care names, so returns can swing quickly as clinical and regulatory news hits.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Travere Therapeutics7.86%$10.04M$5.33B257.58%
56
Neutral
Cogent Biosciences7.52%$9.60M$7.07B241.49%
37
Underperform
Spyre Therapeutics7.48%$9.54M$8.81B504.74%
43
Neutral
Corcept Therapeutics6.89%$8.80M$12.79B65.93%
76
Outperform
LivaNova6.60%$8.42M$4.45B94.84%
63
Neutral
Guardant Health5.48%$6.99M$20.44B291.09%
61
Neutral
BillionToOne, Inc. Class A4.84%$6.18M$6.42B
Cytokinetics3.89%$4.97M$10.01B110.22%
57
Neutral
Mirum Pharmaceuticals3.72%$4.75M$6.87B103.67%
56
Neutral
Axsome Therapeutics3.54%$4.52M$12.07B111.60%
57
Neutral

LFSC Technical Analysis

Technical Analysis Sentiment
Positive
Last Price
Price Trends
50DMA
42.71
Positive
100DMA
39.49
Positive
200DMA
37.49
Positive
Market Momentum
MACD
RSI
STOCH
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For LFSC, the sentiment is Positive. The current price of undefined is equal to the 20-day moving average (MA) of 45.74, equal to the 50-day MA of 42.71, and equal to the 200-day MA of 37.49, indicating a neutral trend. The MACD of ― indicates undefined momentum. The RSI at ― is undefined, neither overbought nor oversold. The STOCH value of ― is undefined, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for LFSC.

LFSC Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$127.62M0.54%
51
Neutral
$863.53M0.65%
63
Neutral
$688.90M0.65%
73
Outperform
$658.20M0.18%
74
Outperform
$643.22M0.65%
71
Outperform
$381.73M0.51%
65
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LFSC
F/M Emerald Life Sciences Innovation ETF
45.55
20.57
82.35%
SAMT
Strategas Macro Thematic Opportunities ETF
GTOP
Goldman Sachs Technology Opportunities ETF
IETC
iShares Evolved US Technology ETF
FEPI
REX FANG & Innovation Equity Premium Income ETF
PINK
Simplify Health Care ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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