tiprankstipranks
Trending News
More News >
Xencor Inc (XNCR)
NASDAQ:XNCR
Advertisement

Xencor (XNCR) AI Stock Analysis

Compare
279 Followers

Top Page

XNCR

Xencor

(NASDAQ:XNCR)

Select Model
Select Model
Select Model
Neutral 50 (OpenAI - 4o)
Rating:50Neutral
Price Target:
$10.00
▼(-19.55% Downside)
Xencor's overall stock score reflects a company with strong revenue growth but significant challenges in profitability and valuation. The technical analysis indicates bullish momentum, but the stock appears overbought, suggesting caution. The lack of earnings call data and corporate events limits additional insights.
Positive Factors
Revenue Growth
Xencor's revenue growth indicates strong market demand and successful partnerships, which are critical for long-term expansion and sustainability.
Technology Platform
Xencor's XmAb technology enhances therapeutic efficacy, providing a competitive edge in developing novel treatments, crucial for future growth.
Balance Sheet Health
A strong balance sheet with low leverage provides financial stability and flexibility to invest in R&D and strategic initiatives.
Negative Factors
Profitability Challenges
Ongoing profitability issues indicate high operational costs or inefficiencies, which may hinder long-term financial performance.
Cash Flow Concerns
Weak cash flow performance may limit Xencor's ability to fund operations and invest in growth, impacting future liquidity and stability.
Return on Equity
Negative ROE suggests that the company is not efficiently using its equity to generate profits, which could affect investor confidence and capital raising.

Xencor (XNCR) vs. SPDR S&P 500 ETF (SPY)

Xencor Business Overview & Revenue Model

Company DescriptionXencor, Inc. is a biopharmaceutical company focused on the development of engineered monoclonal antibodies for the treatment of cancer and autoimmune diseases. The company utilizes its proprietary XmAb technology platform to create novel therapeutics that enhance the efficacy and safety of antibody-based treatments. Xencor's pipeline includes multiple drug candidates that are in various stages of clinical development, targeting significant unmet medical needs in oncology and other therapeutic areas.
How the Company Makes MoneyXencor generates revenue primarily through collaborations and partnerships with larger pharmaceutical companies, which include upfront payments, research funding, and milestone payments tied to the progression of drug candidates through clinical trials. Additionally, the company may earn royalties on future sales of products that are commercialized through these partnerships. Xencor also engages in licensing its XmAb technology platform to other companies, further contributing to its revenue streams. The success of its drug candidates in clinical trials and eventual commercialization are critical factors influencing its earnings.

Xencor Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q4-2023)
|
% Change Since: |
Next Earnings Date:Nov 10, 2025
Earnings Call Sentiment Positive
The earnings call presented a positive outlook with significant pipeline progress and a strong financial position. However, safety concerns with vudalimab and a strategic pause on XmAb564 development were noted.
Q4-2023 Updates
Positive Updates
Strong Financial Position
Xencor ended 2023 with $697 million, providing runway into 2027 due to robust milestone and royalty revenues.
Clinical Pipeline Progress
Significant advancement in bispecific T-cell engagers for solid tumors, including vudalimab in prostate and lung cancer.
Encouraging Vudalimab Data
The prostate cancer monotherapy cohort showed a RECIST response rate of 35% and a disease control rate of 50%.
XmAb Bispecific Technology Development
XmAb bispecific technology shows promise for solid tumor selectivity, with ongoing studies in renal and prostate cancer.
Negative Updates
Safety Concerns with Vudalimab
One case of Grade 5 immune-related hepatitis was reported, raising safety considerations for the treatment.
Pause on XmAb564 Development
Development paused to focus on T-cell engagers, pending further validation of cytokines.
Company Guidance
During Xencor's fourth-quarter 2023 earnings call, the company provided comprehensive guidance on its clinical pipeline and financial outlook. They highlighted a significant focus on the development of bispecific T-cell engagers for solid tumors, including XmAb819 and XmAb808, with ongoing Phase I studies in renal cell carcinoma and prostate cancer, respectively. Vudalimab, a key candidate, showed promising monotherapy results in heavily pre-treated metastatic castrate-resistant prostate cancer patients, with a RECIST response rate of 35% and a PSA90 rate of 25%. Financially, Xencor bolstered its balance sheet through the partial monetization of Ultomiris and Monjuvi royalties, ending 2023 with $697 million, ensuring operational runway until 2027. The company's 2024 priorities include advancing its solid tumor bispecific programs and selecting the next IND candidate, while maintaining a strategic focus on T-cell engager discovery and development.

Xencor Financial Statement Overview

Summary
Xencor's financial performance is mixed. While there is a positive revenue growth rate of 19.38%, the company struggles with profitability, as indicated by negative net profit and EBIT margins. The balance sheet is strong with low leverage, but cash flow issues persist, impacting liquidity.
Income Statement
45
Neutral
Xencor's income statement shows a mixed performance. The company has experienced a positive revenue growth rate of 19.38% TTM, indicating potential growth. However, profitability metrics such as the net profit margin and EBIT margin are negative, reflecting ongoing challenges in achieving profitability. The gross profit margin remains high, suggesting efficient cost management at the gross level, but the negative net profit margin highlights significant expenses or losses further down the income statement.
Balance Sheet
55
Neutral
The balance sheet reveals a relatively low debt-to-equity ratio of 0.11 TTM, indicating conservative leverage and a strong equity position. However, the return on equity is negative, suggesting that the company is not currently generating positive returns on its equity investments. The equity ratio is stable, reflecting a solid capital structure, but the negative ROE indicates challenges in profitability.
Cash Flow
40
Negative
Xencor's cash flow statement shows a decline in free cash flow growth by -18.63% TTM, which is concerning for future liquidity. The operating cash flow to net income ratio is negative, indicating that the company is not generating sufficient cash from operations relative to its net losses. The free cash flow to net income ratio is slightly above 1, suggesting some ability to cover net losses with free cash flow, but overall cash flow performance remains weak.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue164.15M110.49M168.34M164.58M275.11M122.69M
Gross Profit104.70M110.49M-85.26M155.78M267.62M-47.11M
EBITDA-115.24M-186.17M-125.87M-72.16M51.26M-71.00M
Net Income-177.87M-232.62M-126.09M-55.18M82.63M-63.54M
Balance Sheet
Total Assets879.42M951.95M952.69M846.27M838.21M703.24M
Cash, Cash Equivalents and Short-Term Investments443.86M497.77M593.73M623.06M334.11M603.00M
Total Debt212.95M231.95M83.43M59.63M33.97M11.63M
Total Liabilities259.07M277.92M283.56M118.77M104.71M130.80M
Stockholders Equity620.35M677.61M668.80M727.50M733.50M572.44M
Cash Flow
Free Cash Flow-140.81M-208.28M63.86M-18.92M-32.83M-18.77M
Operating Cash Flow-134.18M-202.19M85.11M24.48M-16.85M-5.00M
Investing Cash Flow-52.06M-7.87M-111.06M-119.72M-46.25M100.19M
Financing Cash Flow199.82M197.15M26.18M5.70M43.04M18.04M

Xencor Technical Analysis

Technical Analysis Sentiment
Positive
Last Price12.43
Price Trends
50DMA
9.40
Positive
100DMA
9.03
Positive
200DMA
11.62
Positive
Market Momentum
MACD
1.06
Negative
RSI
63.54
Neutral
STOCH
79.19
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For XNCR, the sentiment is Positive. The current price of 12.43 is above the 20-day moving average (MA) of 11.50, above the 50-day MA of 9.40, and above the 200-day MA of 11.62, indicating a bullish trend. The MACD of 1.06 indicates Negative momentum. The RSI at 63.54 is Neutral, neither overbought nor oversold. The STOCH value of 79.19 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for XNCR.

Xencor Risk Analysis

Xencor disclosed 53 risk factors in its most recent earnings report. Xencor reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Xencor Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
68
Neutral
$1.66B35.9118.17%1218.82%
55
Neutral
$1.12B-46.24%-76.27%22.77%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$995.67M-29.22%-2.07%22.52%
50
Neutral
$439.13M-52.18%187.52%26.32%
48
Neutral
$1.37B-34.71%17.87%41.27%
41
Neutral
$842.69M-55.41%-22.52%-37.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
XNCR
Xencor
12.43
-9.09
-42.24%
DNTH
Dianthus Therapeutics
35.54
7.57
27.06%
AUTL
Autolus Therapeutics
1.62
-2.89
-64.08%
STOK
Stoke Therapeutics
34.94
21.91
168.15%
RLAY
Relay Therapeutics
6.03
-0.77
-11.32%
MRVI
Maravai Lifesciences Holdings
3.23
-5.04
-60.94%

Xencor Corporate Events

Executive/Board Changes
Xencor Appoints Raymond Deshaies to Board of Directors
Positive
Jul 31, 2025

On July 31, 2025, Xencor announced the appointment of Raymond J. Deshaies, Ph.D., to its board of directors. Dr. Deshaies, a renowned biochemist and cell biologist with extensive experience in biotechnology and drug development, previously served as senior vice president of global research at Amgen Inc. His appointment is expected to bolster Xencor’s efforts in advancing its pipeline of XmAb drug candidates through clinical development, leveraging his deep understanding of biological mechanisms and track record of translating scientific insights into transformative medicines.

Executive/Board ChangesShareholder Meetings
Xencor Holds Annual Stockholders Meeting on June 12
Neutral
Jun 13, 2025

On June 12, 2025, Xencor, Inc. held its Annual Meeting of Stockholders, where 94.68% of the company’s shares were represented. During the meeting, stockholders elected eight directors, ratified KPMG LLP as the independent accounting firm, approved an amendment to increase shares in the Equity Incentive Plan by 3,000,000, and supported the executive compensation plan.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 19, 2025