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Vertex Pharmaceuticals Inc. (VRTX)
:VRTX
Tacrolimus, Povetacicept
Primary Membranous Nephropathy
Phase II/III
Not Yet Recruiting
A Study to Evaluate Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Sep 24, 2025
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Vx-407
Autosomal Dominant Polycystic Kidney Disease (Adpkd)
Phase II
Recruiting
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants
Aug 29, 2025
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Drsp/Ee, Ngm/Ee, Vx-407, Lng/Ee, Net/Ee
Autosomal Dominant Polycystic Kidney Disease (Adpkd)
Phase I
Recruiting
Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants
Jul 09, 2025
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Vx-407
Autosomal Dominant Polycystic Kidney Disease (Adpkd)
Phase I
Completed
A Phase 1 Study Evaluating Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants
Jun 06, 2025
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Povetacicept
Healthy Volunteers
Phase I
Completed
A Study to Evaluate the Relative Bioavailability of Povetacicept Formulations and Bioequivalence of Povetacicept Presentations
May 30, 2025
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Vx-670
Myotonic Dystrophy Type 1 (Dm1)
Phase II
Enrolling By Invitation
A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I
Apr 10, 2025
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suzetrigine
Acute Pain
Phase IV
Recruiting
A Single-arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Selected Surgeries
Mar 19, 2025
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suzetrigine
Acute Pain
Phase IV
Recruiting
A Single-Arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Aesthetic or Reconstructive Surgeries
Mar 19, 2025
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14C-Vx-993
Pain
Phase I
Completed
A Study to Evaluate How the Body Processes 14C-VX-993 After a Single Oral Dose
Mar 14, 2025
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Vx-828
Cystic Fibrosis
Phase I
Completed
A Phase 1 Study to Evaluate the Relative Bioavailability of a VX-828 Tablet Formulation
Feb 28, 2025
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Vertex Pharmaceuticals Inc. (VRTX) have in its pipeline
VRTX is currently developing the following drugs: Tacrolimus, Povetacicept, Vx-407, Drsp/Ee, Ngm/Ee, Vx-407, Lng/Ee, Net/Ee. These drug candidates are in various stages of clinical development as the company works toward FDA approval.