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Sangamo Therapeutics (SGMOQ) AI Stock Analysis

SGMOQ

Sangamo Therapeutics

(Other OTC:SGMOQ)

Select Model
Rating:37.8Underperform
Price Target:$0.11▼(-6.03% Downside)
Action:reiterated
Date:10/28/26

The score is driven down primarily by very weak financial performance (declining revenue, large losses, heavy cash burn, and negative equity) and highly adverse corporate events (Chapter 11 bankruptcy and delisting/OTC trading warnings). Technicals also reflect a broader downtrend with negative momentum, and valuation provides little support due to negative earnings and no dividend yield data.

Positive Factors
Strong Gross MarginThe high gross margin indicates that Sangamo’s underlying programs can generate substantial contribution after direct costs if revenue scales. Although operating expenses currently overwhelm this benefit, maintaining strong program-level margins could support improved economics if development assets or partnerships produce recurring revenue.
Negative Factors
Chapter 11 and DelistingChapter 11 and the Nasdaq delisting place Sangamo under court supervision and materially weaken the position of common shareholders. The restructuring creates uncertainty around asset allocation, recoveries, and future ownership, while OTC trading may not reflect eventual shareholder value.

Sangamo Therapeutics (SGMOQ) vs. SPDR S&P 500 ETF (SPY)

-100%-75%-50%-25%0%25%SGMOQ-79.32%SPY+11.79%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
$49.71M
Dividend Yield
―
Average Volume (3M)
2.38M
Price to Earnings (P/E)
-0.2
Beta (1Y)
2.72
Revenue Growth
-45.80%
EPS Growth
-0.16%
Country
US
Employees
142
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Sangamo Therapeutics Business Overview & Revenue Model

Company Description

Sangamo Therapeutics, Inc., a clinical-stage genomic medicine company, focuses on translating science into medicines that transform the lives of patients and families afflicted with serious diseases in the United States. The company's clinical-stage...

How the Company Makes Money

Sangamo Therapeutics primarily makes money through (1) collaboration and licensing arrangements and (2) to a lesser extent, other operating income tied to partnered programs; the company has not historically relied on product sales because its key ca...

Sangamo Therapeutics Earnings Call Summary

Earnings Call Date:May 13, 2026(Q1-2026)|% Change Since:-14.07%|Next Earnings Date:Aug 10, 2026
Earnings Call SentimentNeutral

The call highlights meaningful clinical and regulatory progress for ST-920 (rolling BLA, FDA affirmation of 2-year confirmatory endpoint, durable long-term patient data) and continued advancement across neurology programs and platform technologies. However, material near-term risks center on capital availability and a NASDAQ delisting determination that forced a transition to the OTCQB market. Progress on regulatory and scientific fronts is balanced by significant financing and market-listing challenges that could impact execution and timing.

Positive Updates

BLA Rolling Submission Progress for ST-920 (Fabry)
First 2 modules of the rolling BLA for ST-920 submitted; company states the rolling submission is ~3/5 complete and anticipates completing the BLA submission as early as this summer, subject to adequate funding. FDA affirmed accelerated approval pathway using mean annualized eGFR slope at 52 weeks across all 32 dosed patients.

Negative Updates

NASDAQ Delisting Determination and Market Transition
Received a delisting determination from NASDAQ due to noncompliance with minimum bid requirements; common stock transitioned to trading on the OTCQB Venture Market under the same ticker (SGMO); company intends to appeal at a June hearing.

Company Guidance

Sangamo said the rolling BLA for ST‑920 is in progress with the first two modules submitted, the clinical module (1‑year data) already filed, management characterizing the filing as roughly 3/5 complete and anticipating BLA completion “as early as this summer” subject to securing additional funding; the FDA agreed accelerated approval can be based on mean annualized eGFR slope at 52 weeks across all 32 dosed patients, affirmed no additional confirmatory trial is required, and indicated 104‑week (2‑year) data across those 32 patients may be used for full approval (the last patient reached the 2‑year time point around April). Management also highlighted durability and safety — four patients beyond five years with supraphysiological alpha‑Gal and 17 patients off ERT (some >3 years) — and operational progress in neurology with six sites activated for the Phase I/II STAND (ST‑503), GLP toxicology for ST‑506 completed with analysis ongoing, and MHRA alignment on key matters.

Sangamo Therapeutics Financial Statement Overview

Summary

Very weak financial profile: declining TTM revenue (-12.6%), very large ongoing operating and net losses (TTM EBIT about -$110M; net income about -$123M), heavy and persistent cash burn (TTM operating and free cash flow about -$90M), and a major balance-sheet red flag with stockholders’ equity turning negative (about -$19M), implying elevated financing/dilution risk.

Income Statement

18Very Negative

Balance Sheet

24Negative

Cash Flow

15Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue34.56M39.55M57.80M176.23M111.30M110.70M
Gross Profit34.56M31.95M57.80M176.23M99.19M110.70M
EBITDA-117.46M-115.90M-89.09M-96.80M-179.74M-160.35M
Net Income-123.33M-122.93M-97.94M-257.83M-192.28M-178.29M
Balance Sheet
Total Assets59.97M59.74M101.64M165.32M562.51M721.92M
Cash, Cash Equivalents and Short-Term Investments27.59M20.95M41.92M81.00M277.63M376.55M
Total Debt19.33M26.80M30.57M38.10M43.11M48.08M
Total Liabilities78.92M74.01M78.86M82.43M267.55M346.58M
Stockholders Equity-18.95M-14.27M22.77M82.89M294.96M375.34M
Cash Flow
Free Cash Flow-90.46M-97.31M-67.41M-246.00M-243.80M-256.53M
Operating Cash Flow-90.34M-97.21M-67.14M-224.84M-223.63M-233.25M
Investing Cash Flow-115.00K-102.00K37.52M153.53M59.28M248.20M
Financing Cash Flow89.31M70.75M28.38M14.59M84.66M32.86M

Sangamo Therapeutics Technical Analysis

Technical Analysis SentimentNegative
Last Price0.12

Price Trends

50DMA0.14Negative
100DMA0.12Negative
200DMA0.21Negative

Market Momentum

MACD-0.01Negative
RSI43.73Neutral
STOCH81.82Negative

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SGMOQ, the sentiment is Negative. The current price of 0.12 is below the 20-day moving average (MA) of 0.13, below the 50-day MA of 0.14, and below the 200-day MA of 0.21, indicating a bearish trend. The MACD of -0.01 indicates Negative momentum. The RSI at 43.73 is Neutral, neither overbought nor oversold. The STOCH value of 81.82 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SGMOQ.

Sangamo Therapeutics Risk Analysis

Sangamo Therapeutics disclosed 62 risk factors in its most recent earnings report. Sangamo Therapeutics reported the most risks in the "Tech & Innovation" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Tech & Innovation - Risks related to the company’s reliance on technology and ability to make innovative products

Latest Risks Added

3 New Risks
1.Item 2. Unregistered sales of equity securities, use of proceeds, and issuer purchases of equity securitiesQ1, 2026
2.Item 3. Defaults upon senior securitiesQ1, 2026
3.Item 5. Other informationQ1, 2026

Sangamo Therapeutics Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

SGMOQ against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
BDTXBDTX48Neutral$102.27M-2.40-38.80%―-100.00%-392.92%
CABACABA46Neutral$256.01M-0.95-128.27%――41.56%
ELTXELTX40Underperform$45.51M-0.79-1266.43%――49.43%
SGMOQSGMOQ38Underperform$48.06M-0.206686.36%―-45.80%-0.16%
CRBUCRBU29Underperform$45.37M-0.39-89.11%―10.02%39.66%

* Healthcare Sector Average

Performance Comparison

-50%0%50%SGMOQCABABDTXELTXCRBUDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
SGMOQ and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
SGMOQSangamo Therapeutics, Inc.0.12-0.46-79.93%
CABACabaletta Bio, Inc.1.51-1.50-49.83%
BDTXBlack Diamond Therapeutics, Inc.1.78-2.17-54.94%
ELTXElicio Therapeutics, Inc1.68-7.57-81.84%
CRBUCaribou Biosciences, Inc.0.42-2.01-82.59%

Sangamo Therapeutics Corporate Events

Delistings and Listing ChangesFinancial DisclosuresLegal Proceedings

Sangamo Therapeutics Updates Chapter 11 Operating Reports

Negative
Oct 27, 2026

On June 23, 2026, Sangamo Therapeutics filed for Chapter 11 protection in the U.S. Bankruptcy Court for the District of Delaware, beginning a reorganization process that has left the company operating under court supervision. On October 23, 2026, it...

Business Operations and StrategyDelistings and Listing ChangesFinancial DisclosuresLegal ProceedingsRegulatory Filings and Compliance

Sangamo Therapeutics Highlights Risks Amid Ongoing Bankruptcy

Negative
Oct 16, 2026

On June 23, 2026, Sangamo Therapeutics filed for Chapter 11 protection in the U.S. Bankruptcy Court for the District of Delaware, and on October 14, 2026 it submitted a monthly operating report covering the period from August 1 to August 31, 2026. Th...

Business Operations and StrategyDelistings and Listing ChangesLegal ProceedingsM&A Transactions

Sangamo Therapeutics Completes Fabry Gene Therapy Asset Sale

Negative
Sep 21, 2026

On June 23, 2026, Sangamo Therapeutics, Inc. filed for Chapter 11 bankruptcy protection in the United States Bankruptcy Court for the District of Delaware and has since operated as a debtor-in-possession under court supervision. Following a bid proce...

Business Operations and StrategyDelistings and Listing ChangesFinancial DisclosuresLegal ProceedingsM&A Transactions

Sangamo Therapeutics Completes Key Technology Asset Sale

Negative
Sep 8, 2026

On September 4, 2026, Sangamo Therapeutics completed the court-approved sale of substantially all of its key technology platforms and related intellectual property to Eli Lilly and Company for $50 million in cash and the assumption of certain liabili...

Business Operations and StrategyLegal ProceedingsM&A Transactions

Sangamo Therapeutics Signs Asset Sale Deal Amid Bankruptcy

Negative
Aug 28, 2026

On June 23, 2026, Sangamo Therapeutics filed for Chapter 11 bankruptcy protection in the U.S. Bankruptcy Court for the District of Delaware, launching a court-supervised restructuring process. As part of this process, the company ran a Section 363 au...

Business Operations and StrategyLegal ProceedingsM&A Transactions

Sangamo Concludes Section 363 Asset Sales in Bankruptcy

Negative
Aug 13, 2026

On August 13, 2026, Sangamo Therapeutics, which filed for Chapter 11 protection on June 23, 2026, announced that it had completed a court-supervised Section 363 auction of key assets, selecting winning bids from PTC Therapeutics, Eli Lilly and other...

Delistings and Listing ChangesFinancial DisclosuresLegal Proceedings

Sangamo Therapeutics Reports Post-Bankruptcy Operating Developments

Negative
Aug 12, 2026

As of June 23, 2026, Sangamo Therapeutics filed for voluntary Chapter 11 bankruptcy protection in the U.S. Bankruptcy Court for the District of Delaware, and on August 6, 2026 it submitted its monthly operating report covering June 2026. During this...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 27, 2026