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Septerna, Inc. (SEPN) Stock Statistics & Valuation Metrics

Total Valuation

Septerna, Inc. has a market cap or net worth of $2.05B. The enterprise value is $1.16B.

Market Cap
$2.05B
Enterprise Value
$1.16B

Share Statistics

Septerna, Inc. has 46,676,950 shares outstanding. The number of shares has decreased by -2.65% in one year.

Shares Outstanding
46,676,950
Owned by Insiders
26.54%
Owned by Institutions
18.36%

Financial Efficiency

Septerna, Inc.’s return on equity (ROE) is -0.13 and return on invested capital (ROIC) is -15.80%.

Return on Equity (ROE)
-0.13
Return on Assets (ROA)
-0.08
Return on Invested Capital (ROIC)
-15.80%
Return on Capital Employed (ROCE)
-0.16
Revenue Per Employee
373.59K
Profits Per Employee
-397.39K
Employee Count
123
Asset Turnover
0.08
Inventory Turnover
0.00

Valuation Ratios

The current PE Ratio of Septerna, Inc. is -81.48. Septerna, Inc.’s PEG ratio is -0.45.

PE Ratio
-81.48
PS Ratio
20.77
PB Ratio
5.12
Price to FCF
19.54
Price to Operating Cash Flow
18.69
PEG Ratio
-0.45

Income Statement

In the last 12 months, Septerna, Inc. had revenue of 45.95M and earned -48.88M in profits. Earnings per share was -1.10.

Revenue
45.95M
Gross Profit
45.95M
Operating Income
-80.80M
Pretax Income
-48.87M
Net Income
-48.88M
EBITDA
-47.26M
Earnings Per Share (EPS)
-1.10

Cash Flow

In the last 12 months, operating cash flow was 106.01M and capital expenditures -910,000, giving a free cash flow of 105.10M billion.

Operating Cash Flow
106.01M
Free Cash Flow
105.10M
Free Cash Flow per Share
2.33

Dividends & Yields

Septerna, Inc. pays an annual dividend of ―, resulting in a dividend yield of ―

Dividend Per Share
―
Dividend Yield
―
Payout Ratio
N/A
Free Cash Flow Yield
5.12%
Earnings Yield
-1.22%

Stock Price Statistics

Beta
2.06
52-Week Price Change
104.75%
50-Day Moving Average
38.81
200-Day Moving Average
32.07
Relative Strength Index (RSI)
65.16
Average Volume (3m)
390.71K

Important Dates

Septerna, Inc. upcoming earnings date is Nov 25, 2026, TBA (Not Confirmed).

Last Earnings Date
Aug 10, 2026
Next Earnings Date
Nov 25, 2026
Ex-Dividend Date
―

Financial Position

Septerna, Inc. as a current ratio of 4.73, with Debt / Equity ratio of 6.19%

Current Ratio
4.73
Quick Ratio
4.73
Debt to Market Cap
0.02
Net Debt to EBITDA
2.05
Interest Coverage Ratio
0.00

Taxes

In the past 12 months, Septerna, Inc. has paid 12.00K in taxes.

Income Tax
12.00K
Effective Tax Rate
-0.00

Enterprise Valuation

Septerna, Inc. EV to EBITDA ratio is -50.65, with an EV/FCF ratio of 18.95.

EV to Sales
20.14
EV to EBITDA
-50.65
EV to Free Cash Flow
18.95
EV to Operating Cash Flow
18.79

Balance Sheet

Septerna, Inc. has $372.32M in cash and marketable securities with $22.55M in debt, giving a net cash position of $349.78M billion.

Cash & Marketable Securities
$372.32M
Total Debt
$22.55M
Net Cash
$349.78M
Net Cash Per Share
$7.49
Tangible Book Value Per Share
$8.59

Margins

Gross margin is 99.57%, with operating margin of -44.04%, and net profit margin of -24.51%.

Gross Margin
99.57%
Operating Margin
-44.04%
Pretax Margin
-23.17%
Net Profit Margin
-24.51%
EBITDA Margin
-39.77%
EBIT Margin
-41.44%

Analyst Forecast

The average price target for Septerna, Inc. is $52.88, which is 11.43% higher than the current price. The consensus rating is Strong Buy

Price Target
$52.88
Price Target Upside
20.17% Upside
Analyst Consensus
Strong Buy
Analyst Count
9
Revenue Growth Forecast
13520.11%
EPS Growth Forecast
74.95%

Scores

Smart Score
7
AI Score
62