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TransCode Therapeutics (RNAZ) AI Stock Analysis

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RNAZ

TransCode Therapeutics

(NASDAQ:RNAZ)

Select Model
Rating:49Neutral
Price Target:$11.50▲(721.43% Upside)
Action:reiterated
Date:01/24/26

The score is primarily constrained by weak financial performance (no revenue, widening losses, and ongoing cash burn), with limited valuation support due to continued losses. Offsetting factors include constructive near-term technical momentum and positive corporate developments around the pipeline and planned Phase 2a work, though high volatility and stretched oscillators temper the technical contribution.

Positive Factors
Delivery platform efficacy (glioblastoma preclinical)Published murine glioblastoma results demonstrate the company’s delivery platform can systemically deliver antisense payloads to brain tumors and extend survival. This durable technical validation strengthens the platform’s differentiation and supports advancing indications beyond metastatic disease.
Negative Factors
No revenue; widening net lossesPersistent zero revenue with expanding net losses means the company lacks internal revenue-derived funding and must rely on external capital. Over months this increases dilution risk, constrains investment choices, and places pressure on program prioritization and long-term sustainability.

TransCode Therapeutics (RNAZ) vs. SPDR S&P 500 ETF (SPY)

-100%-75%-50%-25%0%25%50%RNAZ-84.85%SPY+14.28%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$1.48M
Dividend Yield
―
Average Volume (3M)
54.05K
Price to Earnings (P/E)
-0.0
Beta (1Y)
2.76
Revenue Growth
―
EPS Growth
86.74%
Country
US
Employees
12
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

TransCode Therapeutics Business Overview & Revenue Model

Company Description

TransCode Therapeutics, Inc. is a biopharmaceutical firm dedicated to pioneering and marketing therapeutic agents and diagnostic tools specifically aimed at combating and detecting metastatic disease. Central to its pipeline is TTX-MC138, a lead ther...

How the Company Makes Money

null

TransCode Therapeutics Financial Statement Overview

Summary

Very weak operating profile with no revenue, widening net losses through TTM, and persistent negative operating/free cash flow indicating ongoing funding dependence. Low debt helps near-term solvency, but equity volatility (including periods of negative equity) and continued cash burn are major risks.

Income Statement

12Very Negative

Balance Sheet

48Neutral

Cash Flow

18Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Mar 2024Dec 2022Mar 2022
Income Statement
Total Revenue000000
Gross Profit-52.65K0-534.86K-516.75K-98.61K-42.47K
EBITDA-42.30M-34.31M-16.19M-17.97M-17.47M-6.71M
Net Income-42.78M-34.66M-16.75M-18.55M-17.56M-6.84M
Balance Sheet
Total Assets151.01M162.40M7.29M5.17M7.59M22.94M
Cash, Cash Equivalents and Short-Term Investments8.38M17.81M5.81M2.77M4.97M20.83M
Total Debt652.41K038.29K450.57K00
Total Liabilities12.65M152.06M9.31M3.53M4.35M2.53M
Stockholders Equity138.36M10.34M-2.02M1.64M3.24M20.40M
Cash Flow
Free Cash Flow-22.61M-19.52M-13.36M-18.11M-15.86M-5.52M
Operating Cash Flow-22.61M-19.52M-13.34M-18.07M-15.76M-5.27M
Investing Cash Flow-4,436-4,436-21.76K-35.61K-100.92K-251.82K
Financing Cash Flow23.62M31.52M16.40M15.91M5,98925.52M

TransCode Therapeutics Technical Analysis

Technical Analysis SentimentNegative
Last Price1.40

Price Trends

50DMA1.70Negative
100DMA3.51Negative
200DMA5.81Negative

Market Momentum

MACD-0.11Positive
RSI35.07Neutral
STOCH12.80Positive

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RNAZ, the sentiment is Negative. The current price of 1.40 is below the 20-day moving average (MA) of 1.63, below the 50-day MA of 1.70, and below the 200-day MA of 5.81, indicating a bearish trend. The MACD of -0.11 indicates Positive momentum. The RSI at 35.07 is Neutral, neither overbought nor oversold. The STOCH value of 12.80 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for RNAZ.

TransCode Therapeutics Risk Analysis

TransCode Therapeutics disclosed 98 risk factors in its most recent earnings report. TransCode Therapeutics reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

3 New Risks
1.?CKLS controls us and its interests may conflict with ours or yours in the future.Q2, 2026
2.If you purchase our securities, you may be subject to substantial dilution in the book value of your shares of common stock.Q4, 2023
3.There is no public market for any of our pre-funded warrants or our common stock purchase warrantsQ4, 2023

TransCode Therapeutics Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

RNAZ against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
RNAZRNAZ49Neutral$22.86M-0.03-58.08%――86.74%
KPRXKPRX41Neutral$6.11M-0.54-63.39%――19.38%
LYRALYRA41Neutral$337.23K-0.01455.31%―-74.05%73.08%
INABINAB39Underperform$9.73M-0.69-93.66%――81.16%

* Healthcare Sector Average

Performance Comparison

-100%-50%0%50%RNAZKPRXLYRAINABDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
RNAZ and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
RNAZTranscode Therapeutics, Inc.1.40-7.02-83.37%
KPRXKiora Pharmaceuticals, Inc.1.35-0.85-38.64%
LYRALyra Therapeutics, Inc.0.19-3.63-95.03%
INABIn8bio, Inc.0.87-0.77-46.89%

TransCode Therapeutics Corporate Events

Business Operations and StrategyDelistings and Listing ChangesPrivate Placements and FinancingRegulatory Filings and ComplianceShareholder Meetings

TransCode Therapeutics Shareholders Approve Key Capital Measures

Positive
Jul 20, 2026

On July 20, 2026, TransCode Therapeutics held its 2026 Annual Meeting of Stockholders, where 52.1% of the company’s voting power was represented, constituting a quorum for business. All proposals presented were approved, reinforcing the company’s cap...

Business Operations and StrategyRegulatory Filings and Compliance

TransCode Therapeutics Updates Preferred Stock Ownership Limits

Positive
Jul 17, 2026

On July 16, 2026, TransCode Therapeutics, Inc. amended and restated the certificate of designation governing its Series C Non-Voting Convertible Preferred Stock, following consent from a majority of Series C holders and approval by its board. The ame...

Delistings and Listing ChangesRegulatory Filings and ComplianceShareholder Meetings

TransCode Adjourns Annual Meeting Amid Nasdaq Listing Steps

Neutral
Jul 2, 2026

On July 2, 2026, TransCode Therapeutics opened its 2026 Annual Meeting of Stockholders but adjourned it to July 20, 2026, after preliminary results showed all proposals had sufficient support for approval. The postponement was driven by administrativ...

Business Operations and StrategyProduct-Related Announcements

TransCode Highlights Progress of Lead RNA Cancer Therapeutic

Positive
Jun 18, 2026

On June 18, 2026, TransCode Therapeutics posted an investor presentation outlining its progress across three cancer treatment platforms and highlighting its lead RNA therapeutic candidate, TTX-MC138. The Phase 2a-stage antagomiR targets microRNA-10b...

Business Operations and Strategy

TransCode Therapeutics Advances TTX-MC138 After Positive Phase 1a

Positive
Jun 3, 2026

On June 3, 2026, TransCode Therapeutics reported that its Phase 1a dose-escalation trial of lead RNA-based cancer therapeutic TTX-MC138 met its primary safety endpoint with no dose-limiting toxicities in 16 metastatic cancer patients given 86 total d...

Regulatory Filings and ComplianceShareholder Meetings

TransCode Sets Key Deadlines for 2026 Shareholder Meeting

Neutral
Jun 1, 2026

TransCode Therapeutics said it plans to hold its 2026 annual meeting of stockholders on July 2, 2026, with May 28, 2026, set as the record date for shareholders entitled to notice and voting. The company noted that its 2025 annual meeting occurred on...

Delistings and Listing ChangesFinancial DisclosuresRegulatory Filings and Compliance

TransCode Therapeutics Receives Nasdaq Listing Deficiency Notice

Negative
May 22, 2026

On May 19, 2026, TransCode Therapeutics disclosed that it received a deficiency letter from Nasdaq after reporting stockholders’ equity of about $1.25 million as of March 31, 2026, below the $2.5 million minimum required for continued listing on the...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Jan 24, 2026