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QURE Stock Chart & Stats
$51.05
$0.25(0.64%)
At close: 4:00 PM EDT
$51.05
$0.25(0.64%)
Day’s Range― - ―
52-Week Range$8.73 - $71.50
Previous CloseN/A
Volume30.69K
Average Volume (3M)2.50M
Market Cap
$1.63B
Enterprise Value$2.79K
Total Cash (Recent Filing)$810.34M
Total Debt (Recent Filing)$62.83M
Price to Earnings (P/E)―
Beta1.74
Next Earnings
Nov 10, 2026EPS Estimate
-0.92Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-4.04
Shares Outstanding69,366,410
10 Day Avg. Volume5,236,600
30 Day Avg. Volume2,495,067
Financial Highlights & Ratios
PEG Ratio0.23
Price to Book (P/B)6.92
Price to Sales (P/S)85.48
P/FCF Ratio-7.73
Enterprise Value/Market Cap<0.01
Enterprise Value/Revenue<0.01
Enterprise Value/Gross Profit<0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price Target
$59.83Price Target Upside17.21% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering9
EPS Forecast (FY)-3.89
Revenue Forecast (FY)$23.45M
Bulls Say, Bears Say
Bulls Say
AMT-130 Regulatory ProgressFDA alignment and completed U.S. and U.K. submissions materially advance AMT-130 toward potential commercialization. The accelerated pathway could shorten development time for a disease-modifying Huntington’s therapy and establish uniQure’s position in central nervous system gene therapy.
Durable AMT-130 Clinical SignalLonger-term data showing slower Huntington’s progression versus an external control strengthen the case that AMT-130 may provide sustained clinical benefit. If confirmed by regulators and follow-up studies, this could support product differentiation and meaningful future royalty or product revenue.
Extended Cash RunwayThe strengthened liquidity position gives uniQure time to advance AMT-130, conduct the required confirmatory study, and develop other programs without immediate financing pressure. A runway into 2030 also improves strategic flexibility during regulatory review and potential commercialization preparation.
Bears Say
Severe Losses And Cash BurnPersistent operating losses and substantial cash consumption show that the current business is not self-funding. Even with a large cash balance, continued burn can reduce resources available for clinical development and commercialization, increasing dependence on successful execution or future financing.
AMT-191 Dose-limiting ToxicityThe AMT-191 dosing pause creates a material development risk for the Fabry program by delaying dose optimization and adding regulatory work. Although the events resolved with immunosuppression, the toxicity signal could narrow the usable dose range or require additional monitoring.
Confirmatory Trial Execution BurdenAMT-130’s accelerated pathway still depends on rapid execution of a global randomized confirmatory trial. Aligning sites, enrolling patients, and maintaining study quality while preparing for launch could increase operating demands and create a risk that approval or commercialization milestones are delayed.
uniQure News
QURE FAQ
What was uniQure N.V.’s price range in the past 12 months?
uniQure N.V. lowest stock price was $8.73 and its highest was $71.50 in the past 12 months.
What is uniQure N.V.’s market cap?
uniQure N.V.’s market cap is $1.63B.
When is uniQure N.V.’s upcoming earnings report date?
uniQure N.V.’s upcoming earnings report date is Nov 10, 2026 which is in 37 days.
How were uniQure N.V.’s earnings last quarter?
uniQure N.V. released its earnings results on Jul 29, 2026. The company reported -$1.22 earnings per share for the quarter, missing the consensus estimate of -$0.822 by -$0.398.
Is uniQure N.V. overvalued?
According to Wall Street analysts uniQure N.V.’s price is currently Undervalued.
Does uniQure N.V. pay dividends?
uniQure N.V. does not currently pay dividends.
What is uniQure N.V.’s EPS estimate?
uniQure N.V.’s EPS estimate is -0.92.
How many shares outstanding does uniQure N.V. have?
uniQure N.V. has 69,366,410 shares outstanding.
What happened to uniQure N.V.’s price movement after its last earnings report?
uniQure N.V. reported an EPS of -$1.22 in its last earnings report, missing expectations of -$0.822. Following the earnings report the stock price went up 9.302%.
Which hedge fund is a major shareholder of uniQure N.V.?
Currently, no hedge funds are holding shares in QURE
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
uniQure Stock Smart Score
Neutral
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8
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10
Analyst Consensus
Strong Buy
Average Price Target:
$59.83 (17.21% Upside)
$59.83 (17.21% Upside)
Blogger Sentiment
Bullish
QURE Sentiment 63%
Sector Average 65%
Sector Average 65%
Hedge Fund Trend
Increased
By 764.9K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Neutral
Last 7 Days <0.1%
Last 30 Days ▼ 0.5%
Last 30 Days ▼ 0.5%
News Sentiment
Neutral
Bullish news 50%
Bearish news 50%
Bearish news 50%
Technicals
SMA
Positive
20 days / 200 days
Momentum
-56.95%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
68.43%
Trailing 12-Months
Learn more about TipRanks Smart Score
Company Description
uniQure N.V.
uniQure N.V. develops treatments for patients suffering from rare and other devastating diseases in the United States. The company offers HEMGENIX that allows people living with hemophilia B to produce factor IX, which can lower the risk of bleeding. Its lead product candidate is AMT-130, a gene therapy candidate, which is in phase I/II clinical study for the treatment of Huntington’s disease. The company also develops AMT-260, which is in phase I/IIa clinical trial for the treatment of mesial temporal lobe epilepsy; AMT-162, which is in phase I/IIa clinical trial to treat superoxide dismutase enzyme-amyotrophic lateral sclerosis; and AMT-191, an investigational gene therapy candidate which is in phase I/IIa clinical trial for the treatment of fabry disease. It has a licensing agreement with Apic Bio to develop, manufacture, and commercialize intrathecally administered investigational gene therapy for ALS caused by mutations in SOD-1; and development and commercial supply agreement with CLS Bhering. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.
QURE Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
Overall the call conveyed strong positive momentum: regulatory progress (FDA alignment on using 3-year data as the basis for an accelerated BLA), an on-track BLA/MAA submission timeline, upcoming 4-year AMT-130 data, encouraging early efficacy and biological signals in AMT-260 and AMT-191, and a materially strengthened balance sheet with ~$810M cash supporting operations into 2030. Notable challenges include a pause in higher-dose AMT-191 dosing after Grade 3 LFTs (dose-limiting toxicity), mixed early efficacy in the AMT-260 low-dose cohort, increased SG&A to fund commercialization (near-term burn), and the operational/regulatory requirement to have the confirmatory trial well underway at the time of any accelerated approval. Taken together, the positives (regulatory clarity, data momentum, cash runway, early signals) outweigh the manageable clinical and execution risks identified.View all QURE earnings summariesQURE Stock 12 Month Forecast
Average Price Target
$59.83
▲(17.21% Upside)
Technical Analysis
Ownership Overview
2.00% Insiders
12.11% Mutual Funds
53.23% Other Institutional Investors
25.02% Public Companies and
Individual Investors