Successful Phase 2b Trial of Deupirfenidone
PureTech announced unprecedented results from the successful Phase 2b trial of deupirfenidone for Idiopathic Pulmonary Fibrosis (IPF), demonstrating significant slowing of lung function decline over at least 26 weeks with a favorable tolerability profile. The trial showed a 50% greater effect size compared to placebo.
FDA Approval of COBENFY
COBENFY, invented at PureTech for the treatment of schizophrenia in adults, was approved by the FDA, marking a significant advance for patients and validation of PureTech's scientific foundation.
Strong Financial Position and Capital Efficiency
As of March 31, 2025, PureTech had approximately $339.1 million in cash, cash equivalents, and short-term investments, enabling the company to maintain financial discipline and strategic flexibility.
LYT-200 Clinical Progress
Strong Phase 1b trial data for LYT-200 in AML and solid tumors, with positive results including six complete responses in a highly pretreated population.