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Profusa (PFSA)
NASDAQ:PFSA
US Market
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Profusa (PFSA) AI Stock Analysis

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PFSA

Profusa

(NASDAQ:PFSA)

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Neutral 43 (OpenAI - Gpt-5.6Sol)
Rating:43Neutral
Price Target:
$2.50
▼(-50.00% Downside)
Action:Upgraded
Date:09/06/26
PFSA scores low primarily due to very weak financial performance (no revenue, widening losses, negative equity, and continued high cash burn) and bearish technicals (price far below key moving averages with negative MACD). Corporate events provide some support via reduced listing risk and capital-structure improvement, but dilution and financing/execution risk remain significant, while valuation is not meaningfully supportive given ongoing losses and no dividend.
Positive Factors
Diagnostics expansion opportunity
The proposed G3 acquisition could add a commercial-stage diagnostics platform with national CLIA-certified laboratories and recurring provider revenue. If completed, this would broaden Profusa beyond its development-stage biosensor focus and potentially create a more diversified operating base.
Negative Factors
No commercial revenue and widening losses
The absence of recorded revenue indicates that Profusa has not yet reached commercial scale, while the approximately $43 million TTM net loss shows accelerating expense intensity. Without demonstrated sales, near-term operating leverage and self-funded growth remain uncertain.
Read all positive and negative factors
Positive Factors
Negative Factors
Diagnostics expansion opportunity
The proposed G3 acquisition could add a commercial-stage diagnostics platform with national CLIA-certified laboratories and recurring provider revenue. If completed, this would broaden Profusa beyond its development-stage biosensor focus and potentially create a more diversified operating base.
Read all positive factors

Profusa (PFSA) vs. SPDR S&P 500 ETF (SPY)

Profusa Business Overview & Revenue Model

Company Description
Profusa, Inc., a digital health technology company, develops bioengineered sensors for body to detect and continuously transmit clinical-grade data for personal and medical use in the United States. It offers the Lumee Oxygen Platform to monitor c...
How the Company Makes Money
Profusa’s primary monetization model is expected to center on commercialization of its biosensing products and associated system components (e.g., implantable sensor units and external readers/wearables) and, where applicable, related services or ...

Profusa Financial Statement Overview

Summary
Very weak fundamentals: no recorded revenue (annual periods and TTM), materially widening losses in TTM (about -$43.0M), negative stockholders’ equity (about -$27.1M TTM) with a very small asset base (about $1.0M) versus sizable debt (about $14.0M). Cash burn remains heavy (TTM operating cash flow and free cash flow about -$21.0M), implying ongoing reliance on external financing despite some improvement versus 2025.
Income Statement
6
Very Negative
Balance Sheet
9
Very Negative
Cash Flow
12
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.00K0.000.000.000.000.00
EBITDA-35.04M-30.73M-4.81M-6.00M-13.22M-5.05M
Net Income-42.97M-35.82M-9.23M-10.28M-20.22M-10.31M
Balance Sheet
Total Assets1.04M3.77M3.07M1.89M1.03M11.36M
Cash, Cash Equivalents and Short-Term Investments719.00K1.78M191.00K142.00K78.00K856.00K
Total Debt14.00M14.81M48.21M40.40M31.03M24.02M
Total Liabilities28.17M30.43M122.28M111.89M100.80M95.02M
Stockholders Equity-27.13M-26.66M-119.20M-110.00M-99.77M-83.66M
Cash Flow
Free Cash Flow-21.04M-16.26M-2.07M-4.40M-7.70M-10.69M
Operating Cash Flow-20.95M-16.25M-2.07M-4.40M-7.70M-10.69M
Investing Cash Flow-7.43M-2.01M0.00-2.00K0.000.00
Financing Cash Flow28.92M19.84M2.12M4.47M6.92M8.75M

Profusa Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.00
Price Trends
50DMA
5.86
Negative
100DMA
20.62
Negative
200DMA
254.69
Negative
Market Momentum
MACD
-1.41
Positive
RSI
43.12
Neutral
STOCH
17.38
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PFSA, the sentiment is Negative. The current price of 5 is below the 20-day moving average (MA) of 5.32, below the 50-day MA of 5.86, and below the 200-day MA of 254.69, indicating a bearish trend. The MACD of -1.41 indicates Positive momentum. The RSI at 43.12 is Neutral, neither overbought nor oversold. The STOCH value of 17.38 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PFSA.

Profusa Risk Analysis

Profusa disclosed 80 risk factors in its most recent earnings report. Profusa reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Profusa Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
$116.35B22.9310.60%3.04%9.77%12.28%
76
Outperform
$31.33B32.6936.19%15.54%77.43%
73
Outperform
$176.41B33.1510.52%2.41%8.06%-61.33%
54
Neutral
$460.53M-3.89-165.83%90.63%-11.42%
52
Neutral
$137.05M-10.98-50.27%27.98%87.35%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
$1.47M-0.01148.25%72.63%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PFSA
Profusa
1.83
-2,594.67
-99.93%
ABT
Abbott Laboratories
102.03
-27.73
-21.37%
DXCM
Dexcom
86.45
9.90
12.93%
MDT
Medtronic
93.75
2.53
2.77%
SENS
Senseonics Holdings
8.88
-0.10
-1.12%
OWLT
Owlet
4.64
-2.70
-36.78%

Profusa Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Profusa Secures New Convertible Note Financing Agreement
Neutral
Sep 1, 2026
On September 1, 2026, Profusa, Inc. completed an additional closing under a February 11, 2025 securities purchase agreement and issued Ascent Partners Fund LLC a senior secured convertible promissory note with a principal amount of $329,670.33 for...
Delistings and Listing ChangesRegulatory Filings and ComplianceStock Split
Profusa Confirms Continued Compliance With Nasdaq Listing Standards
Positive
Aug 31, 2026
On August 26, 2026, Profusa disclosed that Nasdaq’s Listing Qualifications Department had initially notified the company that its recent 1-for-4 reverse stock split left it with fewer than the 500,000 publicly held shares required under Nasd...
Business Operations and StrategyPrivate Placements and Financing
Profusa Strengthens Capital Structure Through Debt-to-Equity Exchange
Positive
Aug 21, 2026
On August 12, 2026, Profusa entered into a fifth amendment to its 2025 securities purchase agreement with Ascent Partners Fund, updating the amendment effective date, adding a new optional note form and resetting the exercise price of an existing ...
Shareholder MeetingsStock Split
Profusa Announces Approved Reverse Stock Split Implementation
Neutral
Aug 14, 2026
At its annual meeting on June 23, 2026, Profusa’s stockholders approved an amendment enabling a reverse stock split at a ratio within a specified range, with the final one-for-four split later set by the chief executive officer and filed wit...
Business Operations and StrategyDelistings and Listing ChangesM&A TransactionsRegulatory Filings and Compliance
Profusa Secures Option for Major Diagnostics Acquisition
Positive
Jul 31, 2026
On July 31, 2026, Profusa entered into an Option Agreement granting it the right, but not the obligation, to acquire G3 Vision Labs and its diagnostics subsidiaries, which generated an estimated $111 million in 2025 net revenues, in a deal structu...
Business Operations and StrategyExecutive/Board ChangesM&A TransactionsPrivate Placements and Financing
Profusa Plans Strategic Acquisition in Diagnostics Expansion
Positive
Jul 27, 2026
On July 27, 2026, Profusa announced it had signed a non-binding term sheet to acquire a privately held, commercial-stage health diagnostics and toxicology testing company, aiming to form a publicly traded diagnostics business with national CLIA-ce...
Financial DisclosuresRegulatory Filings and ComplianceShareholder MeetingsStock Split
Profusa Implements 1-for-25 Reverse Stock Split on Nasdaq
Neutral
Jul 6, 2026
At its annual meeting of stockholders on June 23, 2026, Profusa received shareholder approval to amend its certificate of incorporation to enable a reverse stock split at a ratio between 1-for-5 and 1-for-200, with the final terms delegated to the...
Business Operations and StrategyExecutive/Board ChangesM&A TransactionsPrivate Placements and FinancingRegulatory Filings and ComplianceShareholder MeetingsStock Split
Profusa Shareholders Approve Reverse Split and Governance Changes
Neutral
Jun 23, 2026
At a virtual special meeting of stockholders held on June 23, 2026, Profusa shareholders elected Lauren Chung as a Class I director to serve until the 2029 annual meeting, with a quorum established from 1.82 million shares represented. Investors a...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 06, 2026