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Profusa (PFSA)
NASDAQ:PFSA
US Market
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Profusa (PFSA) AI Stock Analysis

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PFSA

Profusa

(NASDAQ:PFSA)

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Neutral 41 (OpenAI - Gpt-5.6Sol)
Rating:41Neutral
Price Target:
$2.00
▼(-60.00% Downside)
Action:Reiterated
Date:09/30/26
PFSA scores low primarily due to extremely weak financial performance (no revenue, widening losses, high cash burn, and negative equity with funding risk). Technicals also reflect a sustained downtrend. Corporate events add some offset via improved listing clarity and capital-structure actions plus a potential revenue-scaling acquisition path, but these are conditional and do not outweigh the current fundamentals.
Positive Factors
Tissue-integrated biosensor platform
Profusa’s tissue-integrated sensor addresses continuous physiological monitoring through an implantable device paired with an external reader. If technically validated and commercialized, this platform could support multiple health and performance applications and create a differentiated product foundation.
Negative Factors
No commercial revenue and widening losses
The absence of recorded revenue indicates that Profusa has not yet reached commercial scale, while widening losses and negative gross profit show substantial expense intensity without operating support. This limits evidence of product-market traction and makes near-term profitability dependent on execution or financing.
Read all positive and negative factors
Positive Factors
Negative Factors
Tissue-integrated biosensor platform
Profusa’s tissue-integrated sensor addresses continuous physiological monitoring through an implantable device paired with an external reader. If technically validated and commercialized, this platform could support multiple health and performance applications and create a differentiated product foundation.
Read all positive factors

Profusa (PFSA) vs. SPDR S&P 500 ETF (SPY)

Profusa Business Overview & Revenue Model

Company Description
Profusa, Inc., a digital health technology company, develops bioengineered sensors for body to detect and continuously transmit clinical-grade data for personal and medical use in the United States. It offers the Lumee Oxygen Platform to monitor c...
How the Company Makes Money
Profusa’s primary monetization model is expected to center on commercialization of its biosensing products and associated system components (e.g., implantable sensor units and external readers/wearables) and, where applicable, related services or ...

Profusa Financial Statement Overview

Summary
Very weak fundamentals: no recorded revenue (annual periods and TTM), materially widening losses (TTM net loss about $43.0M), negative gross profit, and heavy ongoing cash burn (TTM operating cash flow and free cash flow about -$21.0M). The balance sheet is highly stressed with consistently negative equity (about -$27.1M TTM) and debt far exceeding the small asset base, implying elevated dilution/refinancing risk despite some debt reduction and modest cash-burn improvement versus 2025.
Income Statement
6
Very Negative
Balance Sheet
9
Very Negative
Cash Flow
12
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.00K0.000.000.000.000.00
EBITDA-35.04M-30.73M-4.81M-6.00M-13.22M-5.05M
Net Income-42.97M-35.82M-9.23M-10.28M-20.22M-10.31M
Balance Sheet
Total Assets1.04M3.77M3.07M1.89M1.03M11.36M
Cash, Cash Equivalents and Short-Term Investments719.00K1.78M191.00K142.00K78.00K856.00K
Total Debt14.00M14.81M48.21M40.40M31.03M24.02M
Total Liabilities28.17M30.43M122.28M111.89M100.80M95.02M
Stockholders Equity-27.13M-26.66M-119.20M-110.00M-99.77M-83.66M
Cash Flow
Free Cash Flow-21.04M-16.26M-2.07M-4.40M-7.70M-10.69M
Operating Cash Flow-20.95M-16.25M-2.07M-4.40M-7.70M-10.69M
Investing Cash Flow-7.43M-2.01M0.00-2.00K0.000.00
Financing Cash Flow28.92M19.84M2.12M4.47M6.92M8.75M

Profusa Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.00
Price Trends
50DMA
4.36
Negative
100DMA
14.71
Negative
200DMA
182.72
Negative
Market Momentum
MACD
-0.88
Negative
RSI
45.01
Neutral
STOCH
17.95
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PFSA, the sentiment is Negative. The current price of 5 is above the 20-day moving average (MA) of 2.32, above the 50-day MA of 4.36, and below the 200-day MA of 182.72, indicating a bearish trend. The MACD of -0.88 indicates Negative momentum. The RSI at 45.01 is Neutral, neither overbought nor oversold. The STOCH value of 17.95 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PFSA.

Profusa Risk Analysis

Profusa disclosed 86 risk factors in its most recent earnings report. Profusa reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Profusa Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
$111.40B21.5310.60%3.28%9.77%12.28%
76
Outperform
$32.69B33.2236.19%―15.54%77.43%
73
Outperform
$174.68B32.1210.52%2.52%8.06%-61.33%
54
Neutral
$531.38M-4.33-165.83%―90.63%-11.42%
52
Neutral
$153.12M-11.86-50.27%―27.98%87.35%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
41
Neutral
$1.37M>-0.01148.25%――72.63%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PFSA
Profusa
2.27
-2,224.48
-99.90%
ABT
Abbott Laboratories
100.95
-29.96
-22.89%
DXCM
Dexcom
86.64
19.35
28.76%
MDT
Medtronic
87.09
-5.09
-5.53%
SENS
Senseonics Holdings
10.05
1.33
15.31%
OWLT
Owlet
5.24
-3.23
-38.13%

Profusa Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Profusa Adds Secured Convertible Debt Financing Agreement
Neutral
Sep 16, 2026
On September 16, 2026, Profusa completed an additional closing under its February 11, 2025 Securities Purchase Agreement with Ascent Partners Fund LLC, issuing a senior secured convertible promissory note with a principal amount of $384,615.38 for...
Delistings and Listing ChangesRegulatory Filings and Compliance
Profusa Regains Nasdaq Compliance, Enters One-Year Monitoring
Neutral
Sep 15, 2026
On September 9, 2026, Profusa, Inc. received confirmation from Nasdaq that it had regained compliance with the Bid Price and Equity listing rules. The determination removes the immediate threat of delisting but places the company under a one-year ...
Business Operations and StrategyPrivate Placements and Financing
Profusa Secures New Convertible Note Financing Agreement
Neutral
Sep 1, 2026
On September 1, 2026, Profusa, Inc. completed an additional closing under a February 11, 2025 securities purchase agreement and issued Ascent Partners Fund LLC a senior secured convertible promissory note with a principal amount of $329,670.33 for...
Delistings and Listing ChangesRegulatory Filings and ComplianceStock Split
Profusa Confirms Continued Compliance With Nasdaq Listing Standards
Positive
Aug 31, 2026
On August 26, 2026, Profusa disclosed that Nasdaq’s Listing Qualifications Department had initially notified the company that its recent 1-for-4 reverse stock split left it with fewer than the 500,000 publicly held shares required under Nasd...
Business Operations and StrategyPrivate Placements and Financing
Profusa Strengthens Capital Structure Through Debt-to-Equity Exchange
Positive
Aug 21, 2026
On August 12, 2026, Profusa entered into a fifth amendment to its 2025 securities purchase agreement with Ascent Partners Fund, updating the amendment effective date, adding a new optional note form and resetting the exercise price of an existing ...
Shareholder MeetingsStock Split
Profusa Announces Approved Reverse Stock Split Implementation
Neutral
Aug 14, 2026
At its annual meeting on June 23, 2026, Profusa’s stockholders approved an amendment enabling a reverse stock split at a ratio within a specified range, with the final one-for-four split later set by the chief executive officer and filed wit...
Business Operations and StrategyDelistings and Listing ChangesM&A TransactionsRegulatory Filings and Compliance
Profusa Secures Option for Major Diagnostics Acquisition
Positive
Jul 31, 2026
On July 31, 2026, Profusa entered into an Option Agreement granting it the right, but not the obligation, to acquire G3 Vision Labs and its diagnostics subsidiaries, which generated an estimated $111 million in 2025 net revenues, in a deal structu...
Business Operations and StrategyExecutive/Board ChangesM&A TransactionsPrivate Placements and Financing
Profusa Plans Strategic Acquisition in Diagnostics Expansion
Positive
Jul 27, 2026
On July 27, 2026, Profusa announced it had signed a non-binding term sheet to acquire a privately held, commercial-stage health diagnostics and toxicology testing company, aiming to form a publicly traded diagnostics business with national CLIA-ce...
Financial DisclosuresRegulatory Filings and ComplianceShareholder MeetingsStock Split
Profusa Implements 1-for-25 Reverse Stock Split on Nasdaq
Neutral
Jul 6, 2026
At its annual meeting of stockholders on June 23, 2026, Profusa received shareholder approval to amend its certificate of incorporation to enable a reverse stock split at a ratio between 1-for-5 and 1-for-200, with the final terms delegated to the...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 30, 2026